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Murcko scaffold

Ring system with 3 rings and 17 atoms

11 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
17
Chemicals
11
With full pages
4
Scaffold SMILES

O=C1CCCc2nc(N3CCNCC3)ncc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1CCCc2nc(N3CCNCC3)ncc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 11 of 11 chemicals

Ethyl 4-(4,7-dimethyl-5-oxo-5,6,7,8-tetrahydroquinazolin-2-yl)piperazine-1-carboxylate chemical structure, C17H24N4O3, CAS 777866-89-4
Ethyl 4-(4,7-dimethyl-5-oxo-5,6,7,8-tetrahydroquinazolin-2-yl)piperazine-1-carboxylate
CAS 777866-89-4C17H24N4O3
Ethyl 4-(4-methyl-5-oxo-7,8-dihydro-6H-quinazolin-2-yl)piperazine-1-carboxylate chemical structure, C16H22N4O3, CAS 777866-88-3
Ethyl 4-(4-methyl-5-oxo-7,8-dihydro-6H-quinazolin-2-yl)piperazine-1-carboxylate
CAS 777866-88-3C16H22N4O3
2-(4-Ethylpiperazin-1-yl)-4-methyl-7,8-dihydroquinazolin-5(6H)-one chemical structure, C15H22N4O, CAS 777866-74-7
2-(4-Ethylpiperazin-1-yl)-4-methyl-7,8-dihydroquinazolin-5(6H)-one
CAS 777866-74-7C15H22N4O
2-(4-Ethylpiperazin-1-yl)-4,7-dimethyl-7,8-dihydroquinazolin-5(6H)-one chemical structure, C16H24N4O, CAS 777866-80-5
2-(4-Ethylpiperazin-1-yl)-4,7-dimethyl-7,8-dihydroquinazolin-5(6H)-one
CAS 777866-80-5C16H24N4O
4-(4-Methyl-5-oxo-5,6,7,8-tetrahydroquinazolin-2-yl)piperazine-1-carbaldehyde chemical structure, C14H18N4O2, CAS 880076-05-1
4-(4-Methyl-5-oxo-5,6,7,8-tetrahydroquinazolin-2-yl)piperazine-1-carbaldehyde
CAS 880076-05-1C14H18N4O2
2-[4-(2-Hydroxyethyl)piperazin-1-yl]-4,7-dimethyl-7,8-dihydro-6H-quinazolin-5-one chemical structure, C16H24N4O2, CAS 886140-25-6
2-[4-(2-Hydroxyethyl)piperazin-1-yl]-4,7-dimethyl-7,8-dihydro-6H-quinazolin-5-one
CAS 886140-25-6C16H24N4O2
2-[4-(2-Hydroxyethyl)piperazin-1-yl]-7,7-dimethyl-7,8-dihydroquinazolin-5(6H)-one chemical structure, C16H24N4O2, CAS 886140-31-4
2-[4-(2-Hydroxyethyl)piperazin-1-yl]-7,7-dimethyl-7,8-dihydroquinazolin-5(6H)-one
CAS 886140-31-4C16H24N4O2
2-[4-(2-Hydroxyethyl)piperazin-1-yl]-7-methyl-7,8-dihydroquinazolin-5(6H)-one chemical structure, C15H22N4O2, CAS 929826-17-5
2-[4-(2-Hydroxyethyl)piperazin-1-yl]-7-methyl-7,8-dihydroquinazolin-5(6H)-one
CAS 929826-17-5C15H22N4O2
2-[4-(2-Hydroxyethyl)piperazin-1-yl]-4,7,7-trimethyl-7,8-dihydroquinazolin-5(6H)-one chemical structure, C17H26N4O2, CAS 919731-74-1
2-[4-(2-Hydroxyethyl)piperazin-1-yl]-4,7,7-trimethyl-7,8-dihydroquinazolin-5(6H)-one
CAS 919731-74-1C17H26N4O2
7-Methyl-2-(4-methylpiperazin-1-yl)-7,8-dihydroquinazolin-5(6H)-one chemical structure, C14H20N4O, CAS 925194-07-6
7-Methyl-2-(4-methylpiperazin-1-yl)-7,8-dihydroquinazolin-5(6H)-one
CAS 925194-07-6C14H20N4O
Ethyl 4-(7-methyl-5-oxo-5,6,7,8-tetrahydroquinazolin-2-yl)piperazine-1-carboxylate chemical structure, C16H22N4O3, CAS 1030518-00-3
Ethyl 4-(7-methyl-5-oxo-5,6,7,8-tetrahydroquinazolin-2-yl)piperazine-1-carboxylate
CAS 1030518-00-3C16H22N4O3