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Murcko scaffold

Ring system with 2 rings and 15 atoms

86 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
15
Chemicals
86
With full pages
3
Scaffold SMILES

c1ccc(CCNc2ncccn2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(CCNc2ncccn2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 86 chemicals

Fenyripol hydrochloride chemical structure, C12H14ClN3O, CAS 2441-88-5
Fenyripol hydrochloride
CAS 2441-88-5C12H14ClN3O
Fenyripol chemical structure, C12H13N3O, CAS 3607-24-7
Fenyripol
CAS 3607-24-7C12H13N3O
5-Chloro-2-[(2-phenylethyl)amino]pyrimidine-4-carboxylic acid chemical structure, C13H12ClN3O2, CAS 327064-08-4
5-Chloro-2-[(2-phenylethyl)amino]pyrimidine-4-carboxylic acid
CAS 327064-08-4C13H12ClN3O2
(5-Bromo-pyrimidin-2-yl)-phenethyl-amine chemical structure, C12H12BrN3, CAS 886366-04-7
(5-Bromo-pyrimidin-2-yl)-phenethyl-amine
CAS 886366-04-7C12H12BrN3
2-[[6-Amino-5-nitro-2-(phenethylamino)pyrimidin-4-yl]amino]ethanol chemical structure, C14H18N6O3, CAS 573696-85-2
2-[[6-Amino-5-nitro-2-(phenethylamino)pyrimidin-4-yl]amino]ethanol
CAS 573696-85-2C14H18N6O3
4-{2-[(Pyrimidin-2-yl)amino]ethyl}benzene-1-sulfonamide chemical structure, C12H14N4O2S, CAS 496867-78-8
4-{2-[(Pyrimidin-2-yl)amino]ethyl}benzene-1-sulfonamide
CAS 496867-78-8C12H14N4O2S
N,N-Dimethyl-1-phenyl-N'-pyrimidin-2-ylethane-1,2-diamine chemical structure, C14H18N4, CAS 848297-53-0
N,N-Dimethyl-1-phenyl-N'-pyrimidin-2-ylethane-1,2-diamine
CAS 848297-53-0C14H18N4
4-(1,1-Dimethylethyl)-N-(2-phenylethyl)-2-pyrimidinamine chemical structure, C16H21N3, CAS 774129-52-1
4-(1,1-Dimethylethyl)-N-(2-phenylethyl)-2-pyrimidinamine
CAS 774129-52-1C16H21N3
Ethyl 4-methyl-2-[(2-phenylethyl)amino]pyrimidine-5-carboxylate chemical structure, C16H19N3O2, CAS 903446-45-7
Ethyl 4-methyl-2-[(2-phenylethyl)amino]pyrimidine-5-carboxylate
CAS 903446-45-7C16H19N3O2
N-[2-(3,4-Dimethoxyphenyl)ethyl]pyrimidin-2-amine chemical structure, C14H17N3O2, CAS 864434-18-4
N-[2-(3,4-Dimethoxyphenyl)ethyl]pyrimidin-2-amine
CAS 864434-18-4C14H17N3O2
N-[2-(3-Methoxyphenyl)ethyl]pyrimidin-2-amine chemical structure, C13H15N3O, CAS 1144444-52-9
N-[2-(3-Methoxyphenyl)ethyl]pyrimidin-2-amine
CAS 1144444-52-9C13H15N3O
N-[2-(2-Methoxyphenyl)ethyl]pyrimidin-2-amine chemical structure, C13H15N3O, CAS 1144466-48-7
N-[2-(2-Methoxyphenyl)ethyl]pyrimidin-2-amine
CAS 1144466-48-7C13H15N3O
2-[(4,6-Dimethylpyrimidin-2-yl)amino]-3-phenylpropanoic acid chemical structure, C15H17N3O2, CAS 1233218-27-3
2-[(4,6-Dimethylpyrimidin-2-yl)amino]-3-phenylpropanoic acid
CAS 1233218-27-3C15H17N3O2
N-Pyrimidin-2-ylphenylalanine chemical structure, C13H13N3O2, CAS 1479005-63-4
N-Pyrimidin-2-ylphenylalanine
CAS 1479005-63-4C13H13N3O2
Methyl 4-methyl-2-(phenethylamino)pyrimidine-5-carboxylate chemical structure, C15H17N3O2, CAS 1158256-08-6
Methyl 4-methyl-2-(phenethylamino)pyrimidine-5-carboxylate
CAS 1158256-08-6C15H17N3O2
4-Methyl-2-[(2-phenylethyl)amino]pyrimidine-5-carboxylic acid chemical structure, C14H15N3O2, CAS 1188977-51-6
4-Methyl-2-[(2-phenylethyl)amino]pyrimidine-5-carboxylic acid
CAS 1188977-51-6C14H15N3O2
5-Ethyl-N-[2-(4-methoxyphenyl)-2-methylpropyl]-2-pyrimidinamine chemical structure, C17H23N3O, CAS 1227056-70-3
5-Ethyl-N-[2-(4-methoxyphenyl)-2-methylpropyl]-2-pyrimidinamine
CAS 1227056-70-3C17H23N3O
N-[2-(4-Methoxyphenyl)ethyl]-4-(trifluoromethyl)pyrimidin-2-amine chemical structure, C14H14F3N3O, CAS 1457281-53-6
N-[2-(4-Methoxyphenyl)ethyl]-4-(trifluoromethyl)pyrimidin-2-amine
CAS 1457281-53-6C14H14F3N3O
N-(2-Phenylethyl)-4-(trifluoromethyl)pyrimidin-2-amine chemical structure, C13H12F3N3, CAS 682790-25-6
N-(2-Phenylethyl)-4-(trifluoromethyl)pyrimidin-2-amine
CAS 682790-25-6C13H12F3N3
N-[2-(3,4-Dimethoxyphenyl)ethyl]-4-methylpyrimidin-2-amine chemical structure, C15H19N3O2, CAS 1405820-87-2
N-[2-(3,4-Dimethoxyphenyl)ethyl]-4-methylpyrimidin-2-amine
CAS 1405820-87-2C15H19N3O2
5-Bromo-N-[2-(4-fluorophenyl)ethyl]pyrimidin-2-amine chemical structure, C12H11BrFN3, CAS 1411360-60-5
5-Bromo-N-[2-(4-fluorophenyl)ethyl]pyrimidin-2-amine
CAS 1411360-60-5C12H11BrFN3
N2-(3,3-dimethyl-1-phenylbutan-2-yl)-5-nitropyrimidine-2,4-diamine chemical structure, C16H21N5O2, CAS 1376340-67-8
N2-(3,3-dimethyl-1-phenylbutan-2-yl)-5-nitropyrimidine-2,4-diamine
CAS 1376340-67-8C16H21N5O2
5-Chloro-N-[2-(3,4-dimethoxyphenyl)ethyl]pyrimidin-2-amine chemical structure, C14H16ClN3O2, CAS 1503871-69-9
5-Chloro-N-[2-(3,4-dimethoxyphenyl)ethyl]pyrimidin-2-amine
CAS 1503871-69-9C14H16ClN3O2
4-(2-((4-Amino-6-methylpyrimidin-2-yl)amino)ethyl)benzenesulfonamide hydrochloride chemical structure, C13H18ClN5O2S, CAS 2034540-05-9
4-(2-((4-Amino-6-methylpyrimidin-2-yl)amino)ethyl)benzenesulfonamide hydrochloride
CAS 2034540-05-9C13H18ClN5O2S