CompoundList
Sign in
Murcko scaffold

Ring system with 2 rings and 10 atoms

62 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
10
Chemicals
62
With full pages
13
Scaffold SMILES

O=c1ccnc2scnn12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1ccnc2scnn12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 62 chemicals

L-Cysteine, S-(7-methyl-5-oxo-5H-1,3,4-thiadiazolo(3,2-a)pyrimidin-2-yl)- chemical structure, C9H10N4O3S2, CAS 75607-63-5
L-Cysteine, S-(7-methyl-5-oxo-5H-1,3,4-thiadiazolo(3,2-a)pyrimidin-2-yl)-
CAS 75607-63-5C9H10N4O3S2
5H-1,3,4-Thiadiazolo(3,2-a)pyrimidin-5-one, 2-(ethylsulfonyl)-7-methyl- chemical structure, C8H9N3O3S2, CAS 63028-49-9
5H-1,3,4-Thiadiazolo(3,2-a)pyrimidin-5-one, 2-(ethylsulfonyl)-7-methyl-
CAS 63028-49-9C8H9N3O3S2
L-Serine, O-(7-methyl-5-oxo-5H-1,3,4-thiadiazolo(3,2-a)pyrimidin-2-yl)- chemical structure, C9H10N4O4S, CAS 98755-30-7
L-Serine, O-(7-methyl-5-oxo-5H-1,3,4-thiadiazolo(3,2-a)pyrimidin-2-yl)-
CAS 98755-30-7C9H10N4O4S
Glycine, N-(7-methyl-5-oxo-5H-1,3,4-thiadiazolo(3,2-a)pyrimidin-2-yl)- chemical structure, C8H8N4O3S, CAS 98755-31-8
Glycine, N-(7-methyl-5-oxo-5H-1,3,4-thiadiazolo(3,2-a)pyrimidin-2-yl)-
CAS 98755-31-8C8H8N4O3S
2-(Chloromethyl)-7-methyl-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-one chemical structure, C7H6ClN3OS, CAS 81516-46-3
2-(Chloromethyl)-7-methyl-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-one
CAS 81516-46-3C7H6ClN3OS
Ethyl (7-methyl-5-oxo-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-2-yl)acetate chemical structure, C10H11N3O3S, CAS 145694-86-6
Ethyl (7-methyl-5-oxo-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-2-yl)acetate
CAS 145694-86-6C10H11N3O3S
2-Amino-7-methyl-5H-(1,3,4)thiadiazolo(3,2-a)pyrimidin-5-one chemical structure, C6H6N4OS, CAS 31737-02-7
2-Amino-7-methyl-5H-(1,3,4)thiadiazolo(3,2-a)pyrimidin-5-one
CAS 31737-02-7C6H6N4OS
6-Acetyl-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-one chemical structure, C7H5N3O2S, CAS 343375-14-4
6-Acetyl-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-one
CAS 343375-14-4C7H5N3O2S
6-Acetyl-2-(methylsulfanyl)-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-one chemical structure, C8H7N3O2S2, CAS 343375-30-4
6-Acetyl-2-(methylsulfanyl)-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-one
CAS 343375-30-4C8H7N3O2S2
6-[(E)-3-(Dimethylamino)prop-2-enoyl]-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-one chemical structure, C10H10N4O2S, CAS 343375-31-5
6-[(E)-3-(Dimethylamino)prop-2-enoyl]-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-one
CAS 343375-31-5C10H10N4O2S
2-Ethoxy-7-methyl-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-one chemical structure, C8H9N3O2S, CAS 75607-64-6
2-Ethoxy-7-methyl-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-one
CAS 75607-64-6C8H9N3O2S
2,7-Dimethyl-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-one chemical structure, C7H7N3OS, CAS 41914-67-4
2,7-Dimethyl-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-one
CAS 41914-67-4C7H7N3OS
5H-1,3,4-Thiadiazolo(3,2-a)pyrimidine-5,7(6H)-dione, 8,8a-dihydro-8-butyl-6-methyl- chemical structure, C10H13N3O2S, CAS 53528-94-2
5H-1,3,4-Thiadiazolo(3,2-a)pyrimidine-5,7(6H)-dione, 8,8a-dihydro-8-butyl-6-methyl-
CAS 53528-94-2C10H13N3O2S
5H-1,3,4-Thiadiazolo(3,2-a)pyrimidine-5,7(6H)-dione, 8,8a-dihydro-6-methyl-8-propyl- chemical structure, C9H11N3O2S, CAS 53528-97-5
5H-1,3,4-Thiadiazolo(3,2-a)pyrimidine-5,7(6H)-dione, 8,8a-dihydro-6-methyl-8-propyl-
CAS 53528-97-5C9H11N3O2S
2-Methyl-5-oxo-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidine-6-carboxylic acid chemical structure, C7H5N3O3S, CAS 446829-82-9
2-Methyl-5-oxo-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidine-6-carboxylic acid
CAS 446829-82-9C7H5N3O3S
Ethyl 2-methyl-5-oxo-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidine-6-carboxylate chemical structure, C9H9N3O3S, CAS 6124-14-7
Ethyl 2-methyl-5-oxo-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidine-6-carboxylate
CAS 6124-14-7C9H9N3O3S
7-(Chloromethyl)-2-methyl-5H-(1,3,4)thiadiazolo(3,2-a)pyrimidin-5-one chemical structure, C7H6ClN3OS, CAS 854035-94-2
7-(Chloromethyl)-2-methyl-5H-(1,3,4)thiadiazolo(3,2-a)pyrimidin-5-one
CAS 854035-94-2C7H6ClN3OS
7-(Chloromethyl)-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-one chemical structure, C6H4ClN3OS, CAS 87572-02-9
7-(Chloromethyl)-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-one
CAS 87572-02-9C6H4ClN3OS
7-(Chloromethyl)-2-ethyl-5H-(1,3,4)thiadiazolo(3,2-a)pyrimidin-5-one chemical structure, C8H8ClN3OS, CAS 869634-07-1
7-(Chloromethyl)-2-ethyl-5H-(1,3,4)thiadiazolo(3,2-a)pyrimidin-5-one
CAS 869634-07-1C8H8ClN3OS
7-Methyl-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-one chemical structure, C6H5N3OS, CAS 35523-75-2
7-Methyl-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-one
CAS 35523-75-2C6H5N3OS
6-Bromo-2,7-dimethyl-5H-[1,3,4]thiadiazolo[3,2-A]pyrimidin-5-one chemical structure, C7H6BrN3OS, CAS 56347-06-9
6-Bromo-2,7-dimethyl-5H-[1,3,4]thiadiazolo[3,2-A]pyrimidin-5-one
CAS 56347-06-9C7H6BrN3OS
5H-1,3,4-Thiadiazolo(3,2-a)pyrimidinium, 8-ethyl-7-hydroxy-5-oxo-, inner salt chemical structure, C7H7N3O2S, CAS 39456-06-9
5H-1,3,4-Thiadiazolo(3,2-a)pyrimidinium, 8-ethyl-7-hydroxy-5-oxo-, inner salt
CAS 39456-06-9C7H7N3O2S
7-(Chloromethyl)-2-(methylthio)-5H-[1,3,4]thiadiazolo[3,2-A]pyrimidin-5-one chemical structure, C7H6ClN3OS2, CAS 87572-21-2
7-(Chloromethyl)-2-(methylthio)-5H-[1,3,4]thiadiazolo[3,2-A]pyrimidin-5-one
CAS 87572-21-2C7H6ClN3OS2
6,7-Dichloro-2-pentylsulfonyl-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-one chemical structure, C10H11Cl2N3O3S2, CAS 112588-25-7
6,7-Dichloro-2-pentylsulfonyl-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-one
CAS 112588-25-7C10H11Cl2N3O3S2