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Murcko scaffold

3-Benzylquinazoline-2,4(1H,3H)-dione scaffold

46 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
19
Chemicals
46
With full pages
5
Scaffold SMILES

O=c1[nH]c2ccccc2c(=O)n1Cc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 3-Benzylquinazoline-2,4(1H,3H)-dione page
Murcko scaffold O=c1[nH]c2ccccc2c(=O)n1Cc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 46 of 46 chemicals

Zenarestat chemical structure, C17H11BrClFN2O4, CAS 112733-06-9
Zenarestat
CAS 112733-06-9C17H11BrClFN2O4
RefChem:381774 chemical structure, C17H16N2O2, CAS 84587-29-1
RefChem:381774
CAS 84587-29-1C17H16N2O2
3-Benzylquinazoline-2,4(1H,3H)-dione chemical structure, C15H12N2O2, CAS 1932-42-9
3-Benzylquinazoline-2,4(1H,3H)-dione
CAS 1932-42-9C15H12N2O2
3-((4-Bromo-2-fluorophenyl)methyl)-7-fluoro-3,4-dihydro-2,4-dioxo-1(2H)-quinazolineacetic acid chemical structure, C17H11BrF2N2O4, CAS 112733-08-1
3-((4-Bromo-2-fluorophenyl)methyl)-7-fluoro-3,4-dihydro-2,4-dioxo-1(2H)-quinazolineacetic acid
CAS 112733-08-1C17H11BrF2N2O4
2-(3-Benzyl-2,4-dioxo-1,2,3,4-tetrahydroquinazolin-1-yl)acetonitrile chemical structure, C17H13N3O2, CAS 892295-10-2
2-(3-Benzyl-2,4-dioxo-1,2,3,4-tetrahydroquinazolin-1-yl)acetonitrile
CAS 892295-10-2C17H13N3O2
3-[(4-Methoxyphenyl)methyl]-2,4-dioxo-1H-quinazoline-7-carboxylic acid chemical structure, C17H14N2O5, CAS 892262-30-5
3-[(4-Methoxyphenyl)methyl]-2,4-dioxo-1H-quinazoline-7-carboxylic acid
CAS 892262-30-5C17H14N2O5
4-[(2,4-Dioxo-1H-quinazolin-3-yl)methyl]-N-(3-methoxypropyl)benzamide chemical structure, C20H21N3O4, CAS 896374-15-5
4-[(2,4-Dioxo-1H-quinazolin-3-yl)methyl]-N-(3-methoxypropyl)benzamide
CAS 896374-15-5C20H21N3O4
N-Butan-2-yl-3-[(4-methoxyphenyl)methyl]-2,4-dioxo-1H-quinazoline-7-carboxamide chemical structure, C21H23N3O4, CAS 892278-13-6
N-Butan-2-yl-3-[(4-methoxyphenyl)methyl]-2,4-dioxo-1H-quinazoline-7-carboxamide
CAS 892278-13-6C21H23N3O4
4-[(1,4-Dihydro-7-nitro-2,4-dioxo-3(2H)-quinazolinyl)methyl]benzonitrile chemical structure, C16H10N4O4, CAS 246540-71-6
4-[(1,4-Dihydro-7-nitro-2,4-dioxo-3(2H)-quinazolinyl)methyl]benzonitrile
CAS 246540-71-6C16H10N4O4
Ethyl {3-[(4-bromo-2-fluorophenyl)methyl]-7-chloro-2,4-dioxo-3,4-dihydroquinazolin-1(2H)-yl}acetate chemical structure, C19H15BrClFN2O4, CAS 112733-28-5
Ethyl {3-[(4-bromo-2-fluorophenyl)methyl]-7-chloro-2,4-dioxo-3,4-dihydroquinazolin-1(2H)-yl}acetate
CAS 112733-28-5C19H15BrClFN2O4
2,4-Dioxo-3-(4-methoxybenzyl)-1,2,3,4-tetrahydroquinazoline chemical structure, C16H14N2O3, CAS 221539-62-4
2,4-Dioxo-3-(4-methoxybenzyl)-1,2,3,4-tetrahydroquinazoline
CAS 221539-62-4C16H14N2O3
N-Butyl-3-(4-methoxybenzyl)-2,4-dioxo-1,2,3,4-tetrahydroquinazoline-7-carboxamide chemical structure, C21H23N3O4, CAS 892274-22-5
N-Butyl-3-(4-methoxybenzyl)-2,4-dioxo-1,2,3,4-tetrahydroquinazoline-7-carboxamide
CAS 892274-22-5C21H23N3O4
N-Isopentyl-3-(4-methoxybenzyl)-2,4-dioxo-1,2,3,4-tetrahydroquinazoline-7-carboxamide chemical structure, C22H25N3O4, CAS 892275-17-1
N-Isopentyl-3-(4-methoxybenzyl)-2,4-dioxo-1,2,3,4-tetrahydroquinazoline-7-carboxamide
CAS 892275-17-1C22H25N3O4
3-[(4-Methoxyphenyl)methyl]-N-(3-methoxypropyl)-2,4-dioxo-1H-quinazoline-7-carboxamide chemical structure, C21H23N3O5, CAS 892275-25-1
3-[(4-Methoxyphenyl)methyl]-N-(3-methoxypropyl)-2,4-dioxo-1H-quinazoline-7-carboxamide
CAS 892275-25-1C21H23N3O5
N-(2-Ethylhexyl)-3-(4-methoxybenzyl)-2,4-dioxo-1,2,3,4-tetrahydroquinazoline-7-carboxamide chemical structure, C25H31N3O4, CAS 892276-04-9
N-(2-Ethylhexyl)-3-(4-methoxybenzyl)-2,4-dioxo-1,2,3,4-tetrahydroquinazoline-7-carboxamide
CAS 892276-04-9C25H31N3O4
2-(3-Benzyl-2,4-dioxoquinazolin-1-yl)-N-(3-methoxypropyl)acetamide chemical structure, C21H23N3O4, CAS 892291-25-7
2-(3-Benzyl-2,4-dioxoquinazolin-1-yl)-N-(3-methoxypropyl)acetamide
CAS 892291-25-7C21H23N3O4
N-(3-Ethoxypropyl)-3-(4-methoxybenzyl)-2,4-dioxo-1,2,3,4-tetrahydroquinazoline-7-carboxamide chemical structure, C22H25N3O5, CAS 892275-56-8
N-(3-Ethoxypropyl)-3-(4-methoxybenzyl)-2,4-dioxo-1,2,3,4-tetrahydroquinazoline-7-carboxamide
CAS 892275-56-8C22H25N3O5
N-(3-Isopropoxypropyl)-3-(4-methoxybenzyl)-2,4-dioxo-1,2,3,4-tetrahydroquinazoline-7-carboxamide chemical structure, C23H27N3O5, CAS 892275-80-8
N-(3-Isopropoxypropyl)-3-(4-methoxybenzyl)-2,4-dioxo-1,2,3,4-tetrahydroquinazoline-7-carboxamide
CAS 892275-80-8C23H27N3O5
3-(4-Fluorobenzyl)quinazoline-2,4(1H,3H)-dione chemical structure, C15H11FN2O2, CAS 945368-81-0
3-(4-Fluorobenzyl)quinazoline-2,4(1H,3H)-dione
CAS 945368-81-0C15H11FN2O2
3-[(4-Methoxyphenyl)methyl]-2,4-dioxo-N-pentyl-1,2,3,4-tetrahydroquinazoline-7-carboxamide chemical structure, C22H25N3O4, CAS 892274-30-5
3-[(4-Methoxyphenyl)methyl]-2,4-dioxo-N-pentyl-1,2,3,4-tetrahydroquinazoline-7-carboxamide
CAS 892274-30-5C22H25N3O4
2-(3-Benzyl-2,4-dioxo-1,2,3,4-tetrahydroquinazolin-1-yl)-N-(butan-2-yl)acetamide chemical structure, C21H23N3O3, CAS 892294-96-1
2-(3-Benzyl-2,4-dioxo-1,2,3,4-tetrahydroquinazolin-1-yl)-N-(butan-2-yl)acetamide
CAS 892294-96-1C21H23N3O3
Methyl 3-(4-methoxybenzyl)-2,4-dioxo-1,2,3,4-tetrahydroquinazoline-6-carboxylate chemical structure, C18H16N2O5, CAS 221540-53-0
Methyl 3-(4-methoxybenzyl)-2,4-dioxo-1,2,3,4-tetrahydroquinazoline-6-carboxylate
CAS 221540-53-0C18H16N2O5
3-(3-Chlorobenzyl)quinazoline-2,4(1H,3H)-dione chemical structure, C15H11ClN2O2, CAS 1177806-44-8
3-(3-Chlorobenzyl)quinazoline-2,4(1H,3H)-dione
CAS 1177806-44-8C15H11ClN2O2
3-(2,5-Dimethoxybenzyl)-2,4(1H,3H)-quinazolinedione chemical structure, C17H16N2O4, CAS 1338653-85-2
3-(2,5-Dimethoxybenzyl)-2,4(1H,3H)-quinazolinedione
CAS 1338653-85-2C17H16N2O4