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Murcko scaffold

Ring system with 4 rings and 27 atoms

29 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
27
Chemicals
29
With full pages
2
Scaffold SMILES

c1ccc(Oc2ccc(Cc3ccc(Oc4ccccc4)cc3)cc2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(Oc2ccc(Cc3ccc(Oc4ccccc4)cc3)cc2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 29 of 29 chemicals

4,4'-(Isopropylidenebis(4,1-phenyleneoxy))dianiline chemical structure, C27H26N2O2, CAS 13080-86-9
4,4'-(Isopropylidenebis(4,1-phenyleneoxy))dianiline
CAS 13080-86-9C27H26N2O2
Benzene, 1,1'-(1-methylethylidene)bis[4-(4-nitrophenoxy)- chemical structure, C27H22N2O6, CAS 20653-11-6
Benzene, 1,1'-(1-methylethylidene)bis[4-(4-nitrophenoxy)-
CAS 20653-11-6C27H22N2O6
Benzenamine, 4,4'-[[2,2,2-trifluoro-1-(trifluoromethyl)ethylidene]bis(4,1-phenyleneoxy)]bis- chemical structure, C27H20F6N2O2, CAS 69563-88-8
Benzenamine, 4,4'-[[2,2,2-trifluoro-1-(trifluoromethyl)ethylidene]bis(4,1-phenyleneoxy)]bis-
CAS 69563-88-8C27H20F6N2O2
1,2-Benzenedicarboxylic acid, 3,3'-((1-methylethylidene)bis(4,1-phenyleneoxy))bis- chemical structure, C31H24O10, CAS 53464-95-2
1,2-Benzenedicarboxylic acid, 3,3'-((1-methylethylidene)bis(4,1-phenyleneoxy))bis-
CAS 53464-95-2C31H24O10
1,2-Benzenedicarboxylic acid, 4,4'-((1-methylethylidene)bis(4,1-phenyleneoxy))bis- chemical structure, C31H24O10, CAS 38103-05-8
1,2-Benzenedicarboxylic acid, 4,4'-((1-methylethylidene)bis(4,1-phenyleneoxy))bis-
CAS 38103-05-8C31H24O10
4,4'-((Propane-2,2-diylbis(4,1-phenylene))bis(oxy))diphthalonitrile chemical structure, C31H20N4O2, CAS 38791-67-2
4,4'-((Propane-2,2-diylbis(4,1-phenylene))bis(oxy))diphthalonitrile
CAS 38791-67-2C31H20N4O2
4-{4-[1-[4-(3,4-Dicyanophenoxy)phenyl]-2,2,2-trifluoro-1-(trifluoromethyl)ethyl]phenoxy}phthalonitrile chemical structure, C31H14F6N4O2, CAS 73265-02-8
4-{4-[1-[4-(3,4-Dicyanophenoxy)phenyl]-2,2,2-trifluoro-1-(trifluoromethyl)ethyl]phenoxy}phthalonitrile
CAS 73265-02-8C31H14F6N4O2
4-(4-{1-[4-(3,4-Dicyanophenoxy)phenyl]-1-methylpropyl}phenoxy)phthalonitrile chemical structure, C32H22N4O2, CAS 354796-80-8
4-(4-{1-[4-(3,4-Dicyanophenoxy)phenyl]-1-methylpropyl}phenoxy)phthalonitrile
CAS 354796-80-8C32H22N4O2
2,2'-Bis[4-(3-aminophenoxy)phenyl]hexafluoropropane chemical structure, C27H20F6N2O2, CAS 88821-04-9
2,2'-Bis[4-(3-aminophenoxy)phenyl]hexafluoropropane
CAS 88821-04-9C27H20F6N2O2
2,2-Bis[4-(3-aminophenoxy)phenyl]propane chemical structure, C27H26N2O2, CAS 87880-61-3
2,2-Bis[4-(3-aminophenoxy)phenyl]propane
CAS 87880-61-3C27H26N2O2
2,2-Bis[4-(3-nitrophenoxy)phenyl]propane chemical structure, C27H22N2O6, CAS 105112-78-5
2,2-Bis[4-(3-nitrophenoxy)phenyl]propane
CAS 105112-78-5C27H22N2O6
2,2-Bis[4-(4-nitrophenoxy)phenyl]hexafluoropropane chemical structure, C27H16F6N2O6, CAS 69563-87-7
2,2-Bis[4-(4-nitrophenoxy)phenyl]hexafluoropropane
CAS 69563-87-7C27H16F6N2O6
1,2-Benzenedicarboxylic acid, 3-(4-(1-(4-(3,4-dicarboxyphenoxy)phenyl)-1-methylethyl)phenoxy)- chemical structure, C31H24O10, CAS 72066-79-6
1,2-Benzenedicarboxylic acid, 3-(4-(1-(4-(3,4-dicarboxyphenoxy)phenyl)-1-methylethyl)phenoxy)-
CAS 72066-79-6C31H24O10
4,4'-(((Perfluoropropane-2,2-diyl)bis(4,1-phenylene))bis(oxy))bis(1-nitro-3-(trifluoromethyl)benzene) chemical structure, C29H14F12N2O6, CAS 125663-07-2
4,4'-(((Perfluoropropane-2,2-diyl)bis(4,1-phenylene))bis(oxy))bis(1-nitro-3-(trifluoromethyl)benzene)
CAS 125663-07-2C29H14F12N2O6
2,2-Bis[4-(4-amino-2-trifluoromethylphenoxy)phenyl]hexafluoropropane chemical structure, C29H18F12N2O2, CAS 94525-07-2
2,2-Bis[4-(4-amino-2-trifluoromethylphenoxy)phenyl]hexafluoropropane
CAS 94525-07-2C29H18F12N2O2
1,1'-(Propane-2,2-diyl)bis[4-(2,4,6-trinitrophenoxy)benzene] chemical structure, C27H18N6O14, CAS 56898-42-1
1,1'-(Propane-2,2-diyl)bis[4-(2,4,6-trinitrophenoxy)benzene]
CAS 56898-42-1C27H18N6O14
1-Azido-4-[4-[2-[4-(4-azidophenoxy)phenyl]propan-2-yl]phenoxy]benzene chemical structure, C27H22N6O2, CAS 71550-57-7
1-Azido-4-[4-[2-[4-(4-azidophenoxy)phenyl]propan-2-yl]phenoxy]benzene
CAS 71550-57-7C27H22N6O2
4,4'-((Propane-2,2-diylbis(4,1-phenylene))bis(oxy))bis(2-methylaniline) chemical structure, C29H30N2O2, CAS 62488-09-9
4,4'-((Propane-2,2-diylbis(4,1-phenylene))bis(oxy))bis(2-methylaniline)
CAS 62488-09-9C29H30N2O2
Tetrasodium 4,4'-[propane-2,2-diylbis(4,1-phenyleneoxy)]di(benzene-1,2-dicarboxylate) chemical structure, C31H20Na4O10, CAS 67892-57-3
Tetrasodium 4,4'-[propane-2,2-diylbis(4,1-phenyleneoxy)]di(benzene-1,2-dicarboxylate)
CAS 67892-57-3C31H20Na4O10
1,1'-(Propane-2,2-diyl)bis[4-(4-isocyanatophenoxy)benzene] chemical structure, C29H22N2O4, CAS 63057-63-6
1,1'-(Propane-2,2-diyl)bis[4-(4-isocyanatophenoxy)benzene]
CAS 63057-63-6C29H22N2O4
1,2-Benzenedicarbonitrile, 3,3a(2)-[(1-methylethylidene)bis(4,1-phenyleneoxy)]bis- chemical structure, C31H20N4O2, CAS 60016-67-3
1,2-Benzenedicarbonitrile, 3,3a(2)-[(1-methylethylidene)bis(4,1-phenyleneoxy)]bis-
CAS 60016-67-3C31H20N4O2
1,2-Benzenedicarboxylic acid, 3,3'-((1-methylethylidene)bis(4,1-phenyleneoxy))bis-, sodium salt (1:4) chemical structure, C31H20Na4O10, CAS 72066-81-0
1,2-Benzenedicarboxylic acid, 3,3'-((1-methylethylidene)bis(4,1-phenyleneoxy))bis-, sodium salt (1:4)
CAS 72066-81-0C31H20Na4O10
5,5'-Carbonyldi(2-benzofuran-1,3-dione)--4,4'-[(1,1,1,3,3,3-hexafluoropropane-2,2-diyl)bis(4,1-phenyleneoxy)]dianiline (1/1) chemical structure, C44H26F6N2O9, CAS 126691-33-6
5,5'-Carbonyldi(2-benzofuran-1,3-dione)--4,4'-[(1,1,1,3,3,3-hexafluoropropane-2,2-diyl)bis(4,1-phenyleneoxy)]dianiline (1/1)
CAS 126691-33-6C44H26F6N2O9
1,2-Benzenedicarboxylic acid, 3-[4-[1-[4-(3,4-dicarboxyphenoxy)phenyl]-1-methylethyl]phenoxy]-, sodium salt (1:4) chemical structure, C31H20Na4O10, CAS 72066-80-9
1,2-Benzenedicarboxylic acid, 3-[4-[1-[4-(3,4-dicarboxyphenoxy)phenyl]-1-methylethyl]phenoxy]-, sodium salt (1:4)
CAS 72066-80-9C31H20Na4O10