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Murcko scaffold

1,2,3,4-Tetrahydro-benzo(b)azepin-5-one scaffold

90 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
12
Chemicals
90
With full pages
3
Scaffold SMILES

O=C1CCCNc2ccccc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1,2,3,4-Tetrahydro-benzo(b)azepin-5-one page
Murcko scaffold O=C1CCCNc2ccccc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 90 chemicals

7,9-Dibromo-1,2,3,4-tetrahydro-5H-1-benzazepin-5-one chemical structure, C10H9Br2NO, CAS 19673-29-1
7,9-Dibromo-1,2,3,4-tetrahydro-5H-1-benzazepin-5-one
CAS 19673-29-1C10H9Br2NO
4,4,7,9-Tetrabromo-1,2,3,4-tetrahydro-5H-1-benzazepin-5-one chemical structure, C10H7Br4NO, CAS 19673-28-0
4,4,7,9-Tetrabromo-1,2,3,4-tetrahydro-5H-1-benzazepin-5-one
CAS 19673-28-0C10H7Br4NO
1-Methyl-1,2,3,4-tetrahydro-5H-1-benzazepin-5-one chemical structure, C11H13NO, CAS 3749-11-9
1-Methyl-1,2,3,4-tetrahydro-5H-1-benzazepin-5-one
CAS 3749-11-9C11H13NO
1-(2-Chloroprop-2-en-1-yl)-1,2,3,4-tetrahydro-5H-1-benzazepin-5-one chemical structure, C13H14ClNO, CAS 54620-87-0
1-(2-Chloroprop-2-en-1-yl)-1,2,3,4-tetrahydro-5H-1-benzazepin-5-one
CAS 54620-87-0C13H14ClNO
1,2,3,4-Tetrahydro-benzo(b)azepin-5-one chemical structure, C10H11NO, CAS 1127-74-8
1,2,3,4-Tetrahydro-benzo(b)azepin-5-one
CAS 1127-74-8C10H11NO
8-Chloro-3,4-dihydro-1H-benzo[b]azepin-5(2H)-one chemical structure, C10H10ClNO, CAS 116815-03-3
8-Chloro-3,4-dihydro-1H-benzo[b]azepin-5(2H)-one
CAS 116815-03-3C10H10ClNO
8-Methoxy-3,4-dihydro-1H-benzo[b]azepin-5(2H)-one chemical structure, C11H13NO2, CAS 187601-84-9
8-Methoxy-3,4-dihydro-1H-benzo[b]azepin-5(2H)-one
CAS 187601-84-9C11H13NO2
Ethyl 7-Chloro-2,3,4,5-tetrahydro-5-oxo-1H-1-benzazepine-4-carboxylate chemical structure, C13H14ClNO3, CAS 792931-76-1
Ethyl 7-Chloro-2,3,4,5-tetrahydro-5-oxo-1H-1-benzazepine-4-carboxylate
CAS 792931-76-1C13H14ClNO3
1-Acetyl-3,4-dihydro-1H-benzo[b]azepin-5(2H)-one chemical structure, C12H13NO2, CAS 1206-74-2
1-Acetyl-3,4-dihydro-1H-benzo[b]azepin-5(2H)-one
CAS 1206-74-2C12H13NO2
7,8-Dimethoxy-3,4-dihydro-1H-benzo[b]azepin-5(2H)-one chemical structure, C12H15NO3, CAS 71089-38-8
7,8-Dimethoxy-3,4-dihydro-1H-benzo[b]azepin-5(2H)-one
CAS 71089-38-8C12H15NO3
1-Acetyl-7,8-dimethoxy-3,4-dihydro-1H-benzo[b]azepin-5(2H)-one chemical structure, C14H17NO4, CAS 71089-39-9
1-Acetyl-7,8-dimethoxy-3,4-dihydro-1H-benzo[b]azepin-5(2H)-one
CAS 71089-39-9C14H17NO4
4,4-Difluoro-2,3,4,5-tetrahydro-1H-1-benzazepin-5-one chemical structure, C10H9F2NO, CAS 168163-95-9
4,4-Difluoro-2,3,4,5-tetrahydro-1H-1-benzazepin-5-one
CAS 168163-95-9C10H9F2NO
tert-Butyl 7-bromo-5-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepine-1-carboxylate chemical structure, C15H18BrNO3, CAS 313724-26-4
tert-Butyl 7-bromo-5-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepine-1-carboxylate
CAS 313724-26-4C15H18BrNO3
7-Bromo-1,2,3,4-tetrahydro-5H-1-benzazepin-5-one chemical structure, C10H10BrNO, CAS 3951-89-1
7-Bromo-1,2,3,4-tetrahydro-5H-1-benzazepin-5-one
CAS 3951-89-1C10H10BrNO
7-Chloro-2,3,4,5-tetrahydro-1H-1-benzazepin-5-one chemical structure, C10H10ClNO, CAS 160129-45-3
7-Chloro-2,3,4,5-tetrahydro-1H-1-benzazepin-5-one
CAS 160129-45-3C10H10ClNO
8-Methyl-3,4-dihydro-1H-benzo[b]azepin-5(2H)-one chemical structure, C11H13NO, CAS 187601-85-0
8-Methyl-3,4-dihydro-1H-benzo[b]azepin-5(2H)-one
CAS 187601-85-0C11H13NO
7,9-Dimethyl-1,2,3,4-tetrahydro-5H-1-benzazepin-5-one chemical structure, C12H15NO, CAS 886367-24-4
7,9-Dimethyl-1,2,3,4-tetrahydro-5H-1-benzazepin-5-one
CAS 886367-24-4C12H15NO
6-Methyl-3,4-dihydro-1H-benzo[b]azepin-5(2H)-one chemical structure, C11H13NO, CAS 1369158-67-7
6-Methyl-3,4-dihydro-1H-benzo[b]azepin-5(2H)-one
CAS 1369158-67-7C11H13NO
9-Chloro-3,4-dihydro-1H-benzo[B]azepin-5(2H)-one chemical structure, C10H10ClNO, CAS 247237-56-5
9-Chloro-3,4-dihydro-1H-benzo[B]azepin-5(2H)-one
CAS 247237-56-5C10H10ClNO
9-Fluoro-3,4-dihydro-1H-benzo[B]azepin-5(2H)-one chemical structure, C10H10FNO, CAS 886366-65-0
9-Fluoro-3,4-dihydro-1H-benzo[B]azepin-5(2H)-one
CAS 886366-65-0C10H10FNO
9-Methoxy-3,4-dihydro-1H-benzo[B]azepin-5(2H)-one chemical structure, C11H13NO2, CAS 886366-68-3
9-Methoxy-3,4-dihydro-1H-benzo[B]azepin-5(2H)-one
CAS 886366-68-3C11H13NO2
9-Methyl-1,2,3,4-tetrahydro-benzo[B]azepin-5-one chemical structure, C11H13NO, CAS 886366-77-4
9-Methyl-1,2,3,4-tetrahydro-benzo[B]azepin-5-one
CAS 886366-77-4C11H13NO
9-Ethyl-1,2,3,4-tetrahydrobenzo[b]azepin-5-one chemical structure, C12H15NO, CAS 886366-80-9
9-Ethyl-1,2,3,4-tetrahydrobenzo[b]azepin-5-one
CAS 886366-80-9C12H15NO
7-Fluoro-2,3,4,5-tetrahydro-1H-1-benzazepin-5-one chemical structure, C10H10FNO, CAS 886366-83-2
7-Fluoro-2,3,4,5-tetrahydro-1H-1-benzazepin-5-one
CAS 886366-83-2C10H10FNO