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Murcko scaffold

1,1'-(1,4-Phenylenebis(methylene))di(1H-imidazole) scaffold

8 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
18
Chemicals
8
With full pages
4
Scaffold SMILES

c1cn(Cc2ccc(Cn3ccnc3)cc2)cn1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1,1'-(1,4-Phenylenebis(methylene))di(1H-imidazole) page
Murcko scaffold c1cn(Cc2ccc(Cn3ccnc3)cc2)cn1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 8 of 8 chemicals

1,1'-((2,5-Dimethyl-1,4-phenylene)bis(methylene))bis(1H-imidazole) chemical structure, C16H18N4, CAS 246017-91-4
1,1'-((2,5-Dimethyl-1,4-phenylene)bis(methylene))bis(1H-imidazole)
CAS 246017-91-4C16H18N4
1-[[4-(Imidazol-1-ylmethyl)-2,5-dimethoxyphenyl]methyl]imidazole chemical structure, C16H18N4O2, CAS 312518-94-8
1-[[4-(Imidazol-1-ylmethyl)-2,5-dimethoxyphenyl]methyl]imidazole
CAS 312518-94-8C16H18N4O2
1-[[4-(Imidazol-1-ylmethyl)-2,5-dimethyl-3-nitrophenyl]methyl]imidazole chemical structure, C16H17N5O2, CAS 332056-26-5
1-[[4-(Imidazol-1-ylmethyl)-2,5-dimethyl-3-nitrophenyl]methyl]imidazole
CAS 332056-26-5C16H17N5O2
1,1'-(1,4-Phenylenebis(methylene))di(1H-imidazole) chemical structure, C14H14N4, CAS 56643-83-5
1,1'-(1,4-Phenylenebis(methylene))di(1H-imidazole)
CAS 56643-83-5C14H14N4
2,4,5-Trichloro-1-[[2,5-dimethyl-4-[(2,4,5-trichloroimidazol-1-yl)methyl]phenyl]methyl]imidazole chemical structure, C16H12Cl6N4, CAS 332056-13-0
2,4,5-Trichloro-1-[[2,5-dimethyl-4-[(2,4,5-trichloroimidazol-1-yl)methyl]phenyl]methyl]imidazole
CAS 332056-13-0C16H12Cl6N4
1,1'-((2,3,5,6-Tetramethyl-1,4-phenylene)bis(methylene))bis(1H-imidazole) chemical structure, C18H22N4, CAS 1012075-54-5
1,1'-((2,3,5,6-Tetramethyl-1,4-phenylene)bis(methylene))bis(1H-imidazole)
CAS 1012075-54-5C18H22N4
1,1'-(1,4-Phenylenebis(methylene))bis(2-methyl-1H-imidazole) chemical structure, C16H18N4, CAS 82410-79-5
1,1'-(1,4-Phenylenebis(methylene))bis(2-methyl-1H-imidazole)
CAS 82410-79-5C16H18N4
1,1'-((2,5-Dibromo-1,4-phenylene)bis(methylene))bis(1H-imidazole) chemical structure, C14H12Br2N4, CAS 2375720-18-4
1,1'-((2,5-Dibromo-1,4-phenylene)bis(methylene))bis(1H-imidazole)
CAS 2375720-18-4C14H12Br2N4