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Murcko scaffold

Ring system with 4 rings and 25 atoms

18 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
25
Chemicals
18
With full pages
5
Scaffold SMILES

O=C(NN=Cc1c[nH]c2ccccc12)c1cc(-c2ccccc2)n[nH]1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NN=Cc1c[nH]c2ccccc12)c1cc(-c2ccccc2)n[nH]1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 18 of 18 chemicals

N'-(1H-Indol-3-ylmethylene)-3-(3-nitrophenyl)-1H-pyrazole-5-carbohydrazide chemical structure, C19H14N6O3, CAS 303106-88-9
N'-(1H-Indol-3-ylmethylene)-3-(3-nitrophenyl)-1H-pyrazole-5-carbohydrazide
CAS 303106-88-9C19H14N6O3
(E)-N'-((1H-Indol-3-yl)methylene)-3-(4-methoxyphenyl)-1H-pyrazole-5-carbohydrazide chemical structure, C20H17N5O2, CAS 1284266-02-9
(E)-N'-((1H-Indol-3-yl)methylene)-3-(4-methoxyphenyl)-1H-pyrazole-5-carbohydrazide
CAS 1284266-02-9C20H17N5O2
5(4-Meo-PH)-2H-pyrazole-3-carboxylic acid (2-ME-1H-indol-3-ylmethylene)hydrazide chemical structure, C21H19N5O2, CAS 5784-16-7
5(4-Meo-PH)-2H-pyrazole-3-carboxylic acid (2-ME-1H-indol-3-ylmethylene)hydrazide
CAS 5784-16-7C21H19N5O2
(E)-3-(4-Isopropoxyphenyl)-N'-((2-methyl-1H-indol-3-yl)methylene)-1H-pyrazole-5-carbohydrazide chemical structure, C23H23N5O2, CAS 384849-32-5
(E)-3-(4-Isopropoxyphenyl)-N'-((2-methyl-1H-indol-3-yl)methylene)-1H-pyrazole-5-carbohydrazide
CAS 384849-32-5C23H23N5O2
(E)-N'-((1H-Indol-3-yl)methylene)-3-(p-tolyl)-1H-pyrazole-5-carbohydrazide chemical structure, C20H17N5O, CAS 306300-77-6
(E)-N'-((1H-Indol-3-yl)methylene)-3-(p-tolyl)-1H-pyrazole-5-carbohydrazide
CAS 306300-77-6C20H17N5O
3-(4-Ethylphenyl)-N'-[(E)-(2-methyl-1H-indol-3-yl)methylidene]-1H-pyrazole-5-carbohydrazide chemical structure, C22H21N5O, CAS 402505-88-8
3-(4-Ethylphenyl)-N'-[(E)-(2-methyl-1H-indol-3-yl)methylidene]-1H-pyrazole-5-carbohydrazide
CAS 402505-88-8C22H21N5O
3-(4-Isobutyl-PH)N'-((2-ME-1H-indol-3-yl)methylene)-1H-pyrazole-5-carbohydrazide chemical structure, C24H25N5O, CAS 303104-73-6
3-(4-Isobutyl-PH)N'-((2-ME-1H-indol-3-yl)methylene)-1H-pyrazole-5-carbohydrazide
CAS 303104-73-6C24H25N5O
(E)-3-(3,4-Dimethoxyphenyl)-N'-((2-methyl-1H-indol-3-yl)methylene)-1H-pyrazole-5-carbohydrazide chemical structure, C22H21N5O3, CAS 634884-64-3
(E)-3-(3,4-Dimethoxyphenyl)-N'-((2-methyl-1H-indol-3-yl)methylene)-1H-pyrazole-5-carbohydrazide
CAS 634884-64-3C22H21N5O3
(E)-N'-((1H-Indol-3-yl)methylene)-3-(4-isopropoxyphenyl)-1H-pyrazole-5-carbohydrazide chemical structure, C22H21N5O2, CAS 1284270-27-4
(E)-N'-((1H-Indol-3-yl)methylene)-3-(4-isopropoxyphenyl)-1H-pyrazole-5-carbohydrazide
CAS 1284270-27-4C22H21N5O2
(E)-N'-((1H-Indol-3-yl)methylene)-3-(4-ethoxy-3-methoxyphenyl)-1H-pyrazole-5-carbohydrazide chemical structure, C22H21N5O3, CAS 1285571-83-6
(E)-N'-((1H-Indol-3-yl)methylene)-3-(4-ethoxy-3-methoxyphenyl)-1H-pyrazole-5-carbohydrazide
CAS 1285571-83-6C22H21N5O3
(E)-3-(4-Ethoxy-3-methoxyphenyl)-N'-((2-methyl-1H-indol-3-yl)methylene)-1H-pyrazole-5-carbohydrazide chemical structure, C23H23N5O3, CAS 1285537-65-6
(E)-3-(4-Ethoxy-3-methoxyphenyl)-N'-((2-methyl-1H-indol-3-yl)methylene)-1H-pyrazole-5-carbohydrazide
CAS 1285537-65-6C23H23N5O3
(E)-N'-((1H-Indol-3-yl)methylene)-3-(4-isopropoxy-3-methoxyphenyl)-1H-pyrazole-5-carbohydrazide chemical structure, C23H23N5O3, CAS 634895-19-5
(E)-N'-((1H-Indol-3-yl)methylene)-3-(4-isopropoxy-3-methoxyphenyl)-1H-pyrazole-5-carbohydrazide
CAS 634895-19-5C23H23N5O3
(E)-3-(4-Isopropoxy-3-methoxyphenyl)-N'-((2-methyl-1H-indol-3-yl)methylene)-1H-pyrazole-5-carbohydrazide chemical structure, C24H25N5O3, CAS 634895-21-9
(E)-3-(4-Isopropoxy-3-methoxyphenyl)-N'-((2-methyl-1H-indol-3-yl)methylene)-1H-pyrazole-5-carbohydrazide
CAS 634895-21-9C24H25N5O3
(E)-N'-((1H-Indol-3-yl)methylene)-3-(4-butoxyphenyl)-1H-pyrazole-5-carbohydrazide chemical structure, C23H23N5O2, CAS 1285683-75-1
(E)-N'-((1H-Indol-3-yl)methylene)-3-(4-butoxyphenyl)-1H-pyrazole-5-carbohydrazide
CAS 1285683-75-1C23H23N5O2
(E)-N'-((1H-Indol-3-yl)methylene)-3-(2-butoxyphenyl)-1H-pyrazole-5-carbohydrazide chemical structure, C23H23N5O2, CAS 1285503-21-0
(E)-N'-((1H-Indol-3-yl)methylene)-3-(2-butoxyphenyl)-1H-pyrazole-5-carbohydrazide
CAS 1285503-21-0C23H23N5O2
(E)-3-(2-Butoxyphenyl)-N'-((2-methyl-1H-indol-3-yl)methylene)-1H-pyrazole-5-carbohydrazide chemical structure, C24H25N5O2, CAS 1284274-73-2
(E)-3-(2-Butoxyphenyl)-N'-((2-methyl-1H-indol-3-yl)methylene)-1H-pyrazole-5-carbohydrazide
CAS 1284274-73-2C24H25N5O2
3-(2-Ethoxyphenyl)-N'-(1H-indol-3-ylmethylene)-1H-pyrazole-5-carbohydrazide chemical structure, C21H19N5O2, CAS 302917-82-4
3-(2-Ethoxyphenyl)-N'-(1H-indol-3-ylmethylene)-1H-pyrazole-5-carbohydrazide
CAS 302917-82-4C21H19N5O2
3-(3-Ethoxyphenyl)-N'-(1H-indol-3-ylmethylene)-1H-pyrazole-5-carbohydrazide chemical structure, C21H19N5O2, CAS 303106-03-8
3-(3-Ethoxyphenyl)-N'-(1H-indol-3-ylmethylene)-1H-pyrazole-5-carbohydrazide
CAS 303106-03-8C21H19N5O2