CompoundList
Sign in
Murcko scaffold

Ring system with 3 rings and 21 atoms

8 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
21
Chemicals
8
With full pages
1
Scaffold SMILES

O=C(CCc1cnc[nH]1)NCCc1c[nH]c2ccccc12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CCc1cnc[nH]1)NCCc1c[nH]c2ccccc12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 8 of 8 chemicals

His-Trp chemical structure, C17H19N5O3, CAS 23403-90-9
His-Trp
CAS 23403-90-9C17H19N5O3
L-Histidyl-L-tryptophyl-N~5~-(diaminomethylidene)-L-ornithyl-L-lysyl-N~5~-(diaminomethylidene)-L-ornithine chemical structure, C35H55N15O6, CAS 380220-35-9
L-Histidyl-L-tryptophyl-N~5~-(diaminomethylidene)-L-ornithyl-L-lysyl-N~5~-(diaminomethylidene)-L-ornithine
CAS 380220-35-9C35H55N15O6
L-Histidyl-L-tryptophyl-L-serinamide chemical structure, C20H25N7O4, CAS 60089-60-3
L-Histidyl-L-tryptophyl-L-serinamide
CAS 60089-60-3C20H25N7O4
H-Gly-His-Trp-Gly-OH chemical structure, C21H25N7O5, CAS 89032-51-9
H-Gly-His-Trp-Gly-OH
CAS 89032-51-9C21H25N7O5
2-((S)-2-((S)-2-Amino-3-(1H-imidazol-4-yl)propanamido)-3-(1H-indol-3-yl)propanamido)acetic acid chemical structure, C19H22N6O4, CAS 89032-48-4
2-((S)-2-((S)-2-Amino-3-(1H-imidazol-4-yl)propanamido)-3-(1H-indol-3-yl)propanamido)acetic acid
CAS 89032-48-4C19H22N6O4
Hwesasxx chemical structure, C43H63N11O13, CAS 542813-14-9
Hwesasxx
CAS 542813-14-9C43H63N11O13
H-His-Trp-OH.2HCl chemical structure, C17H21Cl2N5O3, CAS 1361314-93-3
H-His-Trp-OH.2HCl
CAS 1361314-93-3C17H21Cl2N5O3
H-His-D-Trp(2-Me)-Ala-OH chemical structure, C21H26N6O4, CAS 2606896-37-9
H-His-D-Trp(2-Me)-Ala-OH
CAS 2606896-37-9C21H26N6O4