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Murcko scaffold

Ring system with 3 rings and 17 atoms

16 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
17
Chemicals
16
With full pages
3
Scaffold SMILES

c1ccc(-c2nc[nH]c2-c2ccncc2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(-c2nc[nH]c2-c2ccncc2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 16 of 16 chemicals

4-(4-Fluorophenyl)-5-(pyridin-4-yl)-1H-imidazole chemical structure, C14H10FN3, CAS 181630-93-3
4-(4-Fluorophenyl)-5-(pyridin-4-yl)-1H-imidazole
CAS 181630-93-3C14H10FN3
Pyridine, 4-[5-(4-fluorophenyl)-2-(methylsulfinyl)-1H-imidazol-4-yl]- chemical structure, C15H12FN3OS, CAS 840519-07-5
Pyridine, 4-[5-(4-fluorophenyl)-2-(methylsulfinyl)-1H-imidazol-4-yl]-
CAS 840519-07-5C15H12FN3OS
N-(4-(4-(4-Fluorophenyl)-1-methyl-2-(methylthio)-1H-imidazol-5-yl)pyridin-2-yl)acetamide chemical structure, C18H17FN4OS, CAS 452056-93-8
N-(4-(4-(4-Fluorophenyl)-1-methyl-2-(methylthio)-1H-imidazol-5-yl)pyridin-2-yl)acetamide
CAS 452056-93-8C18H17FN4OS
4-[3-(3-Ethoxypropyl)-5-(4-fluorophenyl)imidazol-4-yl]pyridine chemical structure, C19H20FN3O, CAS 165806-63-3
4-[3-(3-Ethoxypropyl)-5-(4-fluorophenyl)imidazol-4-yl]pyridine
CAS 165806-63-3C19H20FN3O
5-(2-Acetamidopyridin-4-yl)-4-(4-fluorophenyl)-1-methyl-1H-imidazole 3-oxide chemical structure, C17H15FN4O2, CAS 452056-83-6
5-(2-Acetamidopyridin-4-yl)-4-(4-fluorophenyl)-1-methyl-1H-imidazole 3-oxide
CAS 452056-83-6C17H15FN4O2
Cbs-3595 chemical structure, C18H17FN4O2S, CAS 908380-97-2
Cbs-3595
CAS 908380-97-2C18H17FN4O2S
1-(2-(Trimethylsilyl)ethoxymethyl)-4-(4-fluorophenyl)-5-(4-pyridyl)imidazole chemical structure, C20H24FN3OSi, CAS 215303-25-6
1-(2-(Trimethylsilyl)ethoxymethyl)-4-(4-fluorophenyl)-5-(4-pyridyl)imidazole
CAS 215303-25-6C20H24FN3OSi
1-Methyl-4-phenyl-5-(4-pyridyl)imidazole chemical structure, C15H13N3, CAS 152122-36-6
1-Methyl-4-phenyl-5-(4-pyridyl)imidazole
CAS 152122-36-6C15H13N3
4-[1-Methyl-4-[3-(methylsulfinyl)phenyl]-1H-imidazol-5-yl]pyridine chemical structure, C16H15N3OS, CAS 165806-56-4
4-[1-Methyl-4-[3-(methylsulfinyl)phenyl]-1H-imidazol-5-yl]pyridine
CAS 165806-56-4C16H15N3OS
5-(2-(1-Amino-2-methylpropan-2-yl)-5-(pyridin-4-yl)-1H-imidazol-4-yl)-2-chlorophenol chemical structure, C18H19ClN4O, CAS 342434-07-5
5-(2-(1-Amino-2-methylpropan-2-yl)-5-(pyridin-4-yl)-1H-imidazol-4-yl)-2-chlorophenol
CAS 342434-07-5C18H19ClN4O
2-Fluoro-4-(4-(4-fluorophenyl)-2-(methylthio)-1H-imidazol-5-yl)pyridine chemical structure, C15H11F2N3S, CAS 549505-59-1
2-Fluoro-4-(4-(4-fluorophenyl)-2-(methylthio)-1H-imidazol-5-yl)pyridine
CAS 549505-59-1C15H11F2N3S
Methyl 3-[5-(pyridin-4-yl)-1H-imidazol-4-yl]benzoate chemical structure, C16H13N3O2, CAS 1253528-07-2
Methyl 3-[5-(pyridin-4-yl)-1H-imidazol-4-yl]benzoate
CAS 1253528-07-2C16H13N3O2
Methyl 4-[5-(pyridin-4-yl)-1H-imidazol-4-yl]benzoate chemical structure, C16H13N3O2, CAS 1253528-04-9
Methyl 4-[5-(pyridin-4-yl)-1H-imidazol-4-yl]benzoate
CAS 1253528-04-9C16H13N3O2
4-[4-(3-Chlorophenyl)-1-methyl-1H-imidazol-5-yl]pyridine chemical structure, C15H12ClN3, CAS 165806-54-2
4-[4-(3-Chlorophenyl)-1-methyl-1H-imidazol-5-yl]pyridine
CAS 165806-54-2C15H12ClN3
4-[4-(4-Fluorophenyl)-2-(methylthio)-1H-imidazol-5-yl]-2-pyridinamine chemical structure, C15H13FN4S, CAS 944936-56-5
4-[4-(4-Fluorophenyl)-2-(methylthio)-1H-imidazol-5-yl]-2-pyridinamine
CAS 944936-56-5C15H13FN4S
5-(3,4-Dimethoxyphenyl)-4-(2-methylpyridin-4-yl)-1H-imidazol-2-amine chemical structure, C17H18N4O2, CAS 2315421-15-7
5-(3,4-Dimethoxyphenyl)-4-(2-methylpyridin-4-yl)-1H-imidazol-2-amine
CAS 2315421-15-7C17H18N4O2