CompoundList
Sign in
Murcko scaffold

Ring system with 3 rings and 17 atoms

36 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
17
Chemicals
36
With full pages
16
Scaffold SMILES

c1ccc(-n2cnnc2-c2cccnc2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(-n2cnnc2-c2cccnc2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 36 of 36 chemicals

(4-Phenyl-5-pyridin-3-yl-4H-[1,2,4]triazol-3-ylsulfanyl)-acetonitrile chemical structure, C15H11N5S, CAS 333418-52-3
(4-Phenyl-5-pyridin-3-yl-4H-[1,2,4]triazol-3-ylsulfanyl)-acetonitrile
CAS 333418-52-3C15H11N5S
N,N-Dimethyl-2-[(4-phenyl-5-pyridin-3-yl-1,2,4-triazol-3-yl)sulfanyl]acetamide chemical structure, C17H17N5OS, CAS 632292-57-0
N,N-Dimethyl-2-[(4-phenyl-5-pyridin-3-yl-1,2,4-triazol-3-yl)sulfanyl]acetamide
CAS 632292-57-0C17H17N5OS
Ethyl 2-(4-phenyl-5-(3-pyridyl)-1,2,4-triazol-3-ylthio)acetate chemical structure, C17H16N4O2S, CAS 332909-79-2
Ethyl 2-(4-phenyl-5-(3-pyridyl)-1,2,4-triazol-3-ylthio)acetate
CAS 332909-79-2C17H16N4O2S
2-((4-Phenyl-5-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl)sulfanyl)acetic acid chemical structure, C15H12N4O2S, CAS 333418-51-2
2-((4-Phenyl-5-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl)sulfanyl)acetic acid
CAS 333418-51-2C15H12N4O2S
2-{[4-(4-Methoxyphenyl)-5-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide chemical structure, C16H15N5O2S, CAS 333408-40-5
2-{[4-(4-Methoxyphenyl)-5-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide
CAS 333408-40-5C16H15N5O2S
2-{[4-(4-Methoxyphenyl)-5-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetic acid chemical structure, C16H14N4O3S, CAS 333408-91-6
2-{[4-(4-Methoxyphenyl)-5-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetic acid
CAS 333408-91-6C16H14N4O3S
Methyl 2-[4-(4-methoxyphenyl)-5-(3-pyridyl)-1,2,4-triazol-3-ylthio]acetate chemical structure, C17H16N4O3S, CAS 557064-04-7
Methyl 2-[4-(4-methoxyphenyl)-5-(3-pyridyl)-1,2,4-triazol-3-ylthio]acetate
CAS 557064-04-7C17H16N4O3S
Ethyl 2-[[4-(4-methoxyphenyl)-5-(3-pyridinyl)-4H-1,2,4-triazol-3-yl]thio]acetate chemical structure, C18H18N4O3S, CAS 333408-53-0
Ethyl 2-[[4-(4-methoxyphenyl)-5-(3-pyridinyl)-4H-1,2,4-triazol-3-yl]thio]acetate
CAS 333408-53-0C18H18N4O3S
2-((4-(4-Ethoxyphenyl)-5-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl)sulfanyl)acetic acid chemical structure, C17H16N4O3S, CAS 557064-00-3
2-((4-(4-Ethoxyphenyl)-5-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl)sulfanyl)acetic acid
CAS 557064-00-3C17H16N4O3S
N,N-Diethyl-2-[(4-phenyl-5-pyridin-3-yl-1,2,4-triazol-3-yl)sulfanyl]acetamide chemical structure, C19H21N5OS, CAS 799809-40-8
N,N-Diethyl-2-[(4-phenyl-5-pyridin-3-yl-1,2,4-triazol-3-yl)sulfanyl]acetamide
CAS 799809-40-8C19H21N5OS
2-((4-(4-Bromophenyl)-5-(3-pyridinyl)-4H-1,2,4-triazol-3-yl)thio)acetamide chemical structure, C15H12BrN5OS, CAS 477332-62-0
2-((4-(4-Bromophenyl)-5-(3-pyridinyl)-4H-1,2,4-triazol-3-yl)thio)acetamide
CAS 477332-62-0C15H12BrN5OS
1-((4-(4-Ethoxyphenyl)-5-(3-pyridinyl)-4H-1,2,4-triazol-3-yl)sulfanyl)-3,3-dimethyl-2-butanone chemical structure, C21H24N4O2S, CAS 477329-48-9
1-((4-(4-Ethoxyphenyl)-5-(3-pyridinyl)-4H-1,2,4-triazol-3-yl)sulfanyl)-3,3-dimethyl-2-butanone
CAS 477329-48-9C21H24N4O2S
1-((4-(4-Bromophenyl)-5-(3-pyridinyl)-4H-1,2,4-triazol-3-yl)sulfanyl)-3,3-dimethyl-2-butanone chemical structure, C19H19BrN4OS, CAS 477329-71-8
1-((4-(4-Bromophenyl)-5-(3-pyridinyl)-4H-1,2,4-triazol-3-yl)sulfanyl)-3,3-dimethyl-2-butanone
CAS 477329-71-8C19H19BrN4OS
2-((4-(4-BR-PH)-5-(3-Pyridinyl)-4H-1,2,4-triazol-3-yl)thio)-N,N-diethylacetamide chemical structure, C19H20BrN5OS, CAS 477329-97-8
2-((4-(4-BR-PH)-5-(3-Pyridinyl)-4H-1,2,4-triazol-3-yl)thio)-N,N-diethylacetamide
CAS 477329-97-8C19H20BrN5OS
2-((4-(4-Ethoxyphenyl)-5-(3-pyridinyl)-4H-1,2,4-triazol-3-yl)thio)acetamide chemical structure, C17H17N5O2S, CAS 477329-56-9
2-((4-(4-Ethoxyphenyl)-5-(3-pyridinyl)-4H-1,2,4-triazol-3-yl)thio)acetamide
CAS 477329-56-9C17H17N5O2S
Ethyl 4-[(4-phenyl-5-pyridin-3-yl-1,2,4-triazol-3-yl)sulfanyl]butanoate chemical structure, C19H20N4O2S, CAS 457953-31-0
Ethyl 4-[(4-phenyl-5-pyridin-3-yl-1,2,4-triazol-3-yl)sulfanyl]butanoate
CAS 457953-31-0C19H20N4O2S
Isopropyl ((4-(4-bromophenyl)-5-(3-pyridinyl)-4H-1,2,4-triazol-3-yl)thio)acetate chemical structure, C18H17BrN4O2S, CAS 740871-54-9
Isopropyl ((4-(4-bromophenyl)-5-(3-pyridinyl)-4H-1,2,4-triazol-3-yl)thio)acetate
CAS 740871-54-9C18H17BrN4O2S
ET((((4-(4-BR-PH)-5-(3-Pyridinyl)-4H-1,2,4-triazol-3-yl)thio)AC)amino)acetate chemical structure, C19H18BrN5O3S, CAS 578754-67-3
ET((((4-(4-BR-PH)-5-(3-Pyridinyl)-4H-1,2,4-triazol-3-yl)thio)AC)amino)acetate
CAS 578754-67-3C19H18BrN5O3S
N-(2-Methoxyethyl)-2-{[5-(pyridin-3-yl)-4-[3-(trifluoromethyl)phenyl]-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide chemical structure, C19H18F3N5O2S, CAS 875871-66-2
N-(2-Methoxyethyl)-2-{[5-(pyridin-3-yl)-4-[3-(trifluoromethyl)phenyl]-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide
CAS 875871-66-2C19H18F3N5O2S
2-Chloro-5-{5-(methylthio)-4-[3-(trifluoromethyl)phenyl]-4H-1,2,4-triazol-3-yl}pyridine chemical structure, C15H10ClF3N4S, CAS 680216-99-3
2-Chloro-5-{5-(methylthio)-4-[3-(trifluoromethyl)phenyl]-4H-1,2,4-triazol-3-yl}pyridine
CAS 680216-99-3C15H10ClF3N4S
2-Chloro-5-{5-(prop-2-ynylthio)-4-[3-(trifluoromethyl)phenyl]-4H-1,2,4-triazol-3-yl}pyridine chemical structure, C17H10ClF3N4S, CAS 680217-00-9
2-Chloro-5-{5-(prop-2-ynylthio)-4-[3-(trifluoromethyl)phenyl]-4H-1,2,4-triazol-3-yl}pyridine
CAS 680217-00-9C17H10ClF3N4S
1-({5-(6-Chloro-3-pyridyl)-4-[3-(trifluoromethyl)phenyl]-4H-1,2,4-triazol-3-yl}thio)-3,3-dimethylbutan-2-one chemical structure, C20H18ClF3N4OS, CAS 680217-04-3
1-({5-(6-Chloro-3-pyridyl)-4-[3-(trifluoromethyl)phenyl]-4H-1,2,4-triazol-3-yl}thio)-3,3-dimethylbutan-2-one
CAS 680217-04-3C20H18ClF3N4OS
2-(4-Phenyl-5-pyridin-3-yl-4H-[1,2,4]triazol-3-ylsulfanyl)-acetamide chemical structure, C15H13N5OS, CAS 332385-30-5
2-(4-Phenyl-5-pyridin-3-yl-4H-[1,2,4]triazol-3-ylsulfanyl)-acetamide
CAS 332385-30-5C15H13N5OS
N-(1-Cyano-1,2-dimethylpropyl)-2-{[4-(4-ethoxyphenyl)-5-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide chemical structure, C23H26N6O2S, CAS 782464-96-4
N-(1-Cyano-1,2-dimethylpropyl)-2-{[4-(4-ethoxyphenyl)-5-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide
CAS 782464-96-4C23H26N6O2S