CompoundList
Sign in
Murcko scaffold

4-(4-Phenyl-4H-1,2,4-triazol-3-yl)pyridine scaffold

37 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
17
Chemicals
37
With full pages
15
Scaffold SMILES

c1ccc(-n2cnnc2-c2ccncc2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 4-(4-Phenyl-4H-1,2,4-triazol-3-yl)pyridine page
Murcko scaffold c1ccc(-n2cnnc2-c2ccncc2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 37 of 37 chemicals

2-{[4-Phenyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetic acid chemical structure, C15H12N4O2S, CAS 18199-82-1
2-{[4-Phenyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetic acid
CAS 18199-82-1C15H12N4O2S
Ethyl 2-(4-phenyl-5-(4-pyridyl)-1,2,4-triazol-3-ylthio)acetate chemical structure, C17H16N4O2S, CAS 74271-09-3
Ethyl 2-(4-phenyl-5-(4-pyridyl)-1,2,4-triazol-3-ylthio)acetate
CAS 74271-09-3C17H16N4O2S
2-[[4-(2,3-Dimethylphenyl)-5-pyridin-4-yl-1,2,4-triazol-3-yl]sulfanyl]acetamide chemical structure, C17H17N5OS, CAS 570392-24-4
2-[[4-(2,3-Dimethylphenyl)-5-pyridin-4-yl-1,2,4-triazol-3-yl]sulfanyl]acetamide
CAS 570392-24-4C17H17N5OS
2-{[4-(4-Chlorophenyl)-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide chemical structure, C15H12ClN5OS, CAS 498546-22-8
2-{[4-(4-Chlorophenyl)-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide
CAS 498546-22-8C15H12ClN5OS
Methyl 2-(4-phenyl-5-(4-pyridyl)-1,2,4-triazol-3-ylthio)acetate chemical structure, C16H14N4O2S, CAS 148693-78-1
Methyl 2-(4-phenyl-5-(4-pyridyl)-1,2,4-triazol-3-ylthio)acetate
CAS 148693-78-1C16H14N4O2S
Methyl 2-((4-(4-methoxyphenyl)-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)thio)acetate chemical structure, C17H16N4O3S, CAS 496775-98-5
Methyl 2-((4-(4-methoxyphenyl)-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)thio)acetate
CAS 496775-98-5C17H16N4O3S
N,N-Diethyl-2-[[4-(4-methylphenyl)-5-pyridin-4-yl-1,2,4-triazol-3-yl]sulfanyl]acetamide chemical structure, C20H23N5OS, CAS 499124-75-3
N,N-Diethyl-2-[[4-(4-methylphenyl)-5-pyridin-4-yl-1,2,4-triazol-3-yl]sulfanyl]acetamide
CAS 499124-75-3C20H23N5OS
2-((4-(4-CL-PH)-5-(4-Pyridinyl)-4H-1,2,4-triazol-3-yl)thio)-N,N-diethylacetamide chemical structure, C19H20ClN5OS, CAS 476483-81-5
2-((4-(4-CL-PH)-5-(4-Pyridinyl)-4H-1,2,4-triazol-3-yl)thio)-N,N-diethylacetamide
CAS 476483-81-5C19H20ClN5OS
1-{[4-(4-Chlorophenyl)-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}-3,3-dimethylbutan-2-one chemical structure, C19H19ClN4OS, CAS 498546-19-3
1-{[4-(4-Chlorophenyl)-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}-3,3-dimethylbutan-2-one
CAS 498546-19-3C19H19ClN4OS
1-((4-(4-BR-PH)-5-(4-Pyridinyl)-4H-1,2,4-triazol-3-yl)thio)-3,3-DI-ME-2-butanone chemical structure, C19H19BrN4OS, CAS 477330-45-3
1-((4-(4-BR-PH)-5-(4-Pyridinyl)-4H-1,2,4-triazol-3-yl)thio)-3,3-DI-ME-2-butanone
CAS 477330-45-3C19H19BrN4OS
3-{[4-(4-Methoxyphenyl)-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}propanoic acid chemical structure, C17H16N4O3S, CAS 838268-47-6
3-{[4-(4-Methoxyphenyl)-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}propanoic acid
CAS 838268-47-6C17H16N4O3S
3-{[4-Phenyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}propanoic acid chemical structure, C16H14N4O2S, CAS 690249-41-3
3-{[4-Phenyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}propanoic acid
CAS 690249-41-3C16H14N4O2S
3,3-Dimethyl-1-{[4-(4-methylphenyl)-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}butan-2-one chemical structure, C20H22N4OS, CAS 499124-44-6
3,3-Dimethyl-1-{[4-(4-methylphenyl)-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}butan-2-one
CAS 499124-44-6C20H22N4OS
2-((4-(4-Bromophenyl)-5-(4-pyridinyl)-4H-1,2,4-triazol-3-yl)thio)acetamide chemical structure, C15H12BrN5OS, CAS 477329-81-0
2-((4-(4-Bromophenyl)-5-(4-pyridinyl)-4H-1,2,4-triazol-3-yl)thio)acetamide
CAS 477329-81-0C15H12BrN5OS
2-((4-(4-BR-PH)-5-(4-Pyridinyl)-4H-1,2,4-triazol-3-yl)thio)-N,N-diethylacetamide chemical structure, C19H20BrN5OS, CAS 477333-57-6
2-((4-(4-BR-PH)-5-(4-Pyridinyl)-4H-1,2,4-triazol-3-yl)thio)-N,N-diethylacetamide
CAS 477333-57-6C19H20BrN5OS
{2-[4-(4-Chloro-phenyl)-5-pyridin-4-yl-4H-[1,2,4]triazol-3-ylsulfanyl]-acetylamino}-acetic acid ethyl ester chemical structure, C19H18ClN5O3S, CAS 577980-80-4
{2-[4-(4-Chloro-phenyl)-5-pyridin-4-yl-4H-[1,2,4]triazol-3-ylsulfanyl]-acetylamino}-acetic acid ethyl ester
CAS 577980-80-4C19H18ClN5O3S
Ethyl 2-{2-[4-(4-bromophenyl)-5-(4-pyridyl)-1,2,4-triazol-3-ylthio]acetylamino}acetate chemical structure, C19H18BrN5O3S, CAS 578722-63-1
Ethyl 2-{2-[4-(4-bromophenyl)-5-(4-pyridyl)-1,2,4-triazol-3-ylthio]acetylamino}acetate
CAS 578722-63-1C19H18BrN5O3S
4-(4-(4-CL-PH)-5-((2-Methyl-2-propenyl)thio)-4H-1,2,4-triazol-3-yl)pyridine chemical structure, C17H15ClN4S, CAS 676579-34-3
4-(4-(4-CL-PH)-5-((2-Methyl-2-propenyl)thio)-4H-1,2,4-triazol-3-yl)pyridine
CAS 676579-34-3C17H15ClN4S
N,N-Diethyl-2-{[4-phenyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide chemical structure, C19H21N5OS, CAS 874818-16-3
N,N-Diethyl-2-{[4-phenyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide
CAS 874818-16-3C19H21N5OS
N-(2-Methylpropyl)-2-[(4-phenyl-5-pyridin-4-yl-1,2,4-triazol-3-yl)sulfanyl]acetamide chemical structure, C19H21N5OS, CAS 557097-76-4
N-(2-Methylpropyl)-2-[(4-phenyl-5-pyridin-4-yl-1,2,4-triazol-3-yl)sulfanyl]acetamide
CAS 557097-76-4C19H21N5OS
2-((4-(4-Bromophenyl)-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)thio)acetic acid chemical structure, C15H11BrN4O2S, CAS 763139-07-7
2-((4-(4-Bromophenyl)-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)thio)acetic acid
CAS 763139-07-7C15H11BrN4O2S
4-(4-(4-BR-PH)-5-((2-Methyl-2-propenyl)thio)-4H-1,2,4-triazol-3-yl)pyridine chemical structure, C17H15BrN4S, CAS 676441-15-9
4-(4-(4-BR-PH)-5-((2-Methyl-2-propenyl)thio)-4H-1,2,4-triazol-3-yl)pyridine
CAS 676441-15-9C17H15BrN4S
2-[[4-(3-Chloro-2-methylphenyl)-5-pyridin-4-yl-1,2,4-triazol-3-yl]sulfanyl]-N-(2-cyano-3-methylbutan-2-yl)acetamide chemical structure, C22H23ClN6OS, CAS 762256-67-7
2-[[4-(3-Chloro-2-methylphenyl)-5-pyridin-4-yl-1,2,4-triazol-3-yl]sulfanyl]-N-(2-cyano-3-methylbutan-2-yl)acetamide
CAS 762256-67-7C22H23ClN6OS
4-(4-(4-Methylphenyl)-5-((2-ME-2-propenyl)thio)-4H-1,2,4-triazol-3-yl)pyridine chemical structure, C18H18N4S, CAS 676469-52-6
4-(4-(4-Methylphenyl)-5-((2-ME-2-propenyl)thio)-4H-1,2,4-triazol-3-yl)pyridine
CAS 676469-52-6C18H18N4S