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Murcko scaffold

Ring system with 4 rings and 21 atoms

17 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
21
Chemicals
17
With full pages
4
Scaffold SMILES

c1ccc2c(c1)CCc1cccnc1C2C1CCNCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc2c(c1)CCc1cccnc1C2C1CCNCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 17 of 17 chemicals

6-11-Dihydro-11-(1-methylpiperidin-4-yl)-5H-benzo(5,6)cyclohepta(1,2-b)pyridin-11-ol chemical structure, C20H24N2O, CAS 3964-79-2
6-11-Dihydro-11-(1-methylpiperidin-4-yl)-5H-benzo(5,6)cyclohepta(1,2-b)pyridin-11-ol
CAS 3964-79-2C20H24N2O
Fluorodesloratadine chemical structure, C19H20ClFN2, CAS 298220-99-2
Fluorodesloratadine
CAS 298220-99-2C19H20ClFN2
tert-Butyl (R)-4-(3,10-dibromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)piperidine-1-carboxylate chemical structure, C24H27Br2ClN2O2, CAS 273216-60-7
tert-Butyl (R)-4-(3,10-dibromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)piperidine-1-carboxylate
CAS 273216-60-7C24H27Br2ClN2O2
6,15-Dibromo-13-chloro-2-piperidin-4-yl-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaene chemical structure, C19H19Br2ClN2, CAS 193276-49-2
6,15-Dibromo-13-chloro-2-piperidin-4-yl-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaene
CAS 193276-49-2C19H19Br2ClN2
(R)-3,10-Dibromo-8-chloro-11-(piperidin-4-yl)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine chemical structure, C19H19Br2ClN2
(R)-3,10-Dibromo-8-chloro-11-(piperidin-4-yl)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine
C19H19Br2ClN2
Ethyl 4-(6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)piperidine-1-carboxylate chemical structure, C22H26N2O2, CAS 201466-35-5
Ethyl 4-(6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)piperidine-1-carboxylate
CAS 201466-35-5C22H26N2O2
Loratadine impurity 5 chemical structure, C22H25ClN2O2, CAS 167891-69-2
Loratadine impurity 5
CAS 167891-69-2C22H25ClN2O2
8-Chloro-11-(1-methyl-piperidin-4-yl)-6,11-dihydro-5hbenzo(5,6)cyclohepta(1,2-b)pyridin-11-ol chemical structure, C20H23ClN2O, CAS 38089-93-9
8-Chloro-11-(1-methyl-piperidin-4-yl)-6,11-dihydro-5hbenzo(5,6)cyclohepta(1,2-b)pyridin-11-ol
CAS 38089-93-9C20H23ClN2O
Loratadine impurity 25 chemical structure, C20H23ClN2, CAS 170727-68-1
Loratadine impurity 25
CAS 170727-68-1C20H23ClN2
11-Fluoro dihydroloratadine chemical structure, C22H24ClFN2O2, CAS 125743-80-8
11-Fluoro dihydroloratadine
CAS 125743-80-8C22H24ClFN2O2
Desloratadine impurity 7 chemical structure, C20H22ClFN2, CAS 125743-81-9
Desloratadine impurity 7
CAS 125743-81-9C20H22ClFN2
8-Chloro-3-methoxy-11-(1-methyl-4-piperidinyl)-6,11-dihydro-5H-benzo[5,6]-cyclohepta[1,2-b]pyridin-11-ol chemical structure, C21H25ClN2O2, CAS 165739-71-9
8-Chloro-3-methoxy-11-(1-methyl-4-piperidinyl)-6,11-dihydro-5H-benzo[5,6]-cyclohepta[1,2-b]pyridin-11-ol
CAS 165739-71-9C21H25ClN2O2
8-Chloro-3-methoxy-11-(1-methyl-4-piperidinyl)-6,11-dihydro-5H-benzo[5,6]-cyclohepta[1,2-b]pyridin-11-ol-d4 chemical structure, C21H25ClN2O2, CAS 1189492-69-0
8-Chloro-3-methoxy-11-(1-methyl-4-piperidinyl)-6,11-dihydro-5H-benzo[5,6]-cyclohepta[1,2-b]pyridin-11-ol-d4
CAS 1189492-69-0C21H25ClN2O2
Ethyl 4-(8-chloro-6,11-dihydro-11-hydroxy-5H-benzo(5,6)cyclohepta(1,2-b)pyridin-11-yl)-1-piperidinecarboxylate chemical structure, C22H25ClN2O3, CAS 133284-74-9
Ethyl 4-(8-chloro-6,11-dihydro-11-hydroxy-5H-benzo(5,6)cyclohepta(1,2-b)pyridin-11-yl)-1-piperidinecarboxylate
CAS 133284-74-9C22H25ClN2O3
Ethyl (R)-4-(8-chloro-11-hydroxy-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)piperidine-1-carboxylate chemical structure, C22H25ClN2O3, CAS 2514964-03-3
Ethyl (R)-4-(8-chloro-11-hydroxy-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)piperidine-1-carboxylate
CAS 2514964-03-3C22H25ClN2O3
Desloratadine EP impurity A hcl chemical structure, C19H21Cl2FN2, CAS 2250242-44-3
Desloratadine EP impurity A hcl
CAS 2250242-44-3C19H21Cl2FN2
11-Hydroxy dihydro desloratadine chemical structure, C19H21ClN2O, CAS 153200-97-6
11-Hydroxy dihydro desloratadine
CAS 153200-97-6C19H21ClN2O