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Murcko scaffold

Ring system with 3 rings and 19 atoms

13 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
19
Chemicals
13
With full pages
11
Scaffold SMILES

O=c1cc(CNc2ccccc2)c2ccccc2[nH]1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1cc(CNc2ccccc2)c2ccccc2[nH]1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 13 of 13 chemicals

N-(4-Methoxyphenyl)-N-[(2-oxo-1H-quinolin-4-yl)methyl]propanamide chemical structure, C20H20N2O3, CAS 333982-58-4
N-(4-Methoxyphenyl)-N-[(2-oxo-1H-quinolin-4-yl)methyl]propanamide
CAS 333982-58-4C20H20N2O3
4-(p-Tolylamino-methyl)-1H-quinolin-2-one chemical structure, C17H16N2O, CAS 333984-13-7
4-(p-Tolylamino-methyl)-1H-quinolin-2-one
CAS 333984-13-7C17H16N2O
N-(2-Methylphenyl)-N-[(2-oxo-1H-quinolin-4-yl)methyl]propanamide chemical structure, C20H20N2O2, CAS 713126-83-1
N-(2-Methylphenyl)-N-[(2-oxo-1H-quinolin-4-yl)methyl]propanamide
CAS 713126-83-1C20H20N2O2
N-(2,4-Dimethylphenyl)-2-methyl-N-[(2-oxo-1H-quinolin-4-yl)methyl]propanamide chemical structure, C22H24N2O2, CAS 847243-62-3
N-(2,4-Dimethylphenyl)-2-methyl-N-[(2-oxo-1H-quinolin-4-yl)methyl]propanamide
CAS 847243-62-3C22H24N2O2
N-(2-Methylphenyl)-N-[(2-oxo-1H-quinolin-4-yl)methyl]acetamide chemical structure, C19H18N2O2, CAS 714939-64-7
N-(2-Methylphenyl)-N-[(2-oxo-1H-quinolin-4-yl)methyl]acetamide
CAS 714939-64-7C19H18N2O2
2-Methyl-N-(4-methylphenyl)-N-[(2-oxo-1H-quinolin-4-yl)methyl]propanamide chemical structure, C21H22N2O2, CAS 847175-16-0
2-Methyl-N-(4-methylphenyl)-N-[(2-oxo-1H-quinolin-4-yl)methyl]propanamide
CAS 847175-16-0C21H22N2O2
2-Methyl-N-(3-methylphenyl)-N-[(2-oxo-1H-quinolin-4-yl)methyl]propanamide chemical structure, C21H22N2O2, CAS 848682-54-2
2-Methyl-N-(3-methylphenyl)-N-[(2-oxo-1H-quinolin-4-yl)methyl]propanamide
CAS 848682-54-2C21H22N2O2
2-Methyl-N-(2-methylphenyl)-N-[(2-oxo-1H-quinolin-4-yl)methyl]propanamide chemical structure, C21H22N2O2, CAS 848871-29-4
2-Methyl-N-(2-methylphenyl)-N-[(2-oxo-1H-quinolin-4-yl)methyl]propanamide
CAS 848871-29-4C21H22N2O2
2-Chloro-N-(2,4-dimethylphenyl)-N-[(2-oxo-1H-quinolin-4-yl)methyl]acetamide chemical structure, C20H19ClN2O2, CAS 714928-41-3
2-Chloro-N-(2,4-dimethylphenyl)-N-[(2-oxo-1H-quinolin-4-yl)methyl]acetamide
CAS 714928-41-3C20H19ClN2O2
4-(((4-Methoxyphenyl)amino)methyl)quinolin-2-ol chemical structure, C17H16N2O2, CAS 333982-41-5
4-(((4-Methoxyphenyl)amino)methyl)quinolin-2-ol
CAS 333982-41-5C17H16N2O2
N-(2,4-Dimethylphenyl)-N-[(2-oxo-1H-quinolin-4-yl)methyl]propanamide chemical structure, C21H22N2O2, CAS 848219-47-6
N-(2,4-Dimethylphenyl)-N-[(2-oxo-1H-quinolin-4-yl)methyl]propanamide
CAS 848219-47-6C21H22N2O2
N-(2-Methylphenyl)-N-[(2-oxo-1H-quinolin-4-yl)methyl]butanamide chemical structure, C21H22N2O2, CAS 714922-23-3
N-(2-Methylphenyl)-N-[(2-oxo-1H-quinolin-4-yl)methyl]butanamide
CAS 714922-23-3C21H22N2O2
4-[(4-Chloroanilino)methyl]quinolin-2(1H)-one chemical structure, C16H13ClN2O, CAS 333984-67-1
4-[(4-Chloroanilino)methyl]quinolin-2(1H)-one
CAS 333984-67-1C16H13ClN2O