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Murcko scaffold

P-Xylylene scaffold

31 chemicals on CompoundList share this ring system.

Rings
1
Scaffold atoms
8
Chemicals
31
With full pages
9
Scaffold SMILES

C=c1ccc(=C)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the p-Xylylene page
Murcko scaffold C=c1ccc(=C)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 31 of 31 chemicals

Tetracyanoquinodimethane chemical structure, C12H4N4, CAS 1518-16-7
Tetracyanoquinodimethane
CAS 1518-16-7C12H4N4
1,4-Benzenedicarbonitrile, 2,3,5,6-tetramethyl-, N1,N4-dioxide chemical structure, C12H12N2O2, CAS 2904-60-1
1,4-Benzenedicarbonitrile, 2,3,5,6-tetramethyl-, N1,N4-dioxide
CAS 2904-60-1C12H12N2O2
p-Xylylene chemical structure, C8H8, CAS 502-86-3
p-Xylylene
CAS 502-86-3C8H8
1,4-Cyclohexadiene, 1,4-dimethyl-3,6-bis(methylene)- chemical structure, C10H12, CAS 63238-49-3
1,4-Cyclohexadiene, 1,4-dimethyl-3,6-bis(methylene)-
CAS 63238-49-3C10H12
Terephthalonitrile N,N'-dioxide chemical structure, C8H4N2O2, CAS 3729-34-8
Terephthalonitrile N,N'-dioxide
CAS 3729-34-8C8H4N2O2
Propanedinitrile, 2,2'-(2-methyl-2,5-cyclohexadiene-1,4-diylidene)bis- chemical structure, C13H6N4, CAS 1518-13-4
Propanedinitrile, 2,2'-(2-methyl-2,5-cyclohexadiene-1,4-diylidene)bis-
CAS 1518-13-4C13H6N4
2,5-Dimethyl-7,7,8,8-tetracyanoquinodimethane chemical structure, C14H8N4, CAS 1487-82-7
2,5-Dimethyl-7,7,8,8-tetracyanoquinodimethane
CAS 1487-82-7C14H8N4
Propanedinitrile, 2,2'-(2,5-diethyl-2,5-cyclohexadiene-1,4-diylidene)bis- chemical structure, C16H12N4, CAS 56403-73-7
Propanedinitrile, 2,2'-(2,5-diethyl-2,5-cyclohexadiene-1,4-diylidene)bis-
CAS 56403-73-7C16H12N4
2,3,5,6-Tetrafluoro-7,7,8,8-tetracyanoquinodimethane chemical structure, C12F4N4, CAS 29261-33-4
2,3,5,6-Tetrafluoro-7,7,8,8-tetracyanoquinodimethane
CAS 29261-33-4C12F4N4
Tetraethyl 2,2'-(cyclohexa-2,5-diene-1,4-diylidene)dipropanedioate chemical structure, C20H24O8, CAS 7237-25-4
Tetraethyl 2,2'-(cyclohexa-2,5-diene-1,4-diylidene)dipropanedioate
CAS 7237-25-4C20H24O8
2,5-Difluoro-7,7,8,8-tetracyanoquinodimethane chemical structure, C12H2F2N4, CAS 73318-02-2
2,5-Difluoro-7,7,8,8-tetracyanoquinodimethane
CAS 73318-02-2C12H2F2N4
2,2'-(2,5-Dibromocyclohexa-2,5-diene-1,4-diylidene)dimalononitrile chemical structure, C12H2Br2N4, CAS 56403-70-4
2,2'-(2,5-Dibromocyclohexa-2,5-diene-1,4-diylidene)dimalononitrile
CAS 56403-70-4C12H2Br2N4
2,2'-(Cyclohexa-2,5-diene-1,4-diylidene)dipropanedinitrile--2-(2H-1,3-dithiol-2-ylidene)-2H-1,3-dithiole (1/1) chemical structure, C18H8N4S4, CAS 40210-84-2
2,2'-(Cyclohexa-2,5-diene-1,4-diylidene)dipropanedinitrile--2-(2H-1,3-dithiol-2-ylidene)-2H-1,3-dithiole (1/1)
CAS 40210-84-2C18H8N4S4
N-(3-Cyano-3-(4-(dicyanomethyl)phenyl)-2-propenylidene)-N-ethyl-ethaniminium inner salt chemical structure, C17H16N4, CAS 174280-29-6
N-(3-Cyano-3-(4-(dicyanomethyl)phenyl)-2-propenylidene)-N-ethyl-ethaniminium inner salt
CAS 174280-29-6C17H16N4
2,2'-(2,3,5,6-Tetramethylcyclohexa-2,5-diene-1,4-diylidene)dimalononitrile chemical structure, C16H12N4, CAS 97218-71-8
2,2'-(2,3,5,6-Tetramethylcyclohexa-2,5-diene-1,4-diylidene)dimalononitrile
CAS 97218-71-8C16H12N4
2,2'-(2,3-Dimethylcyclohexa-2,5-diene-1,4-diylidene)dipropanedinitrile chemical structure, C14H8N4, CAS 138048-66-5
2,2'-(2,3-Dimethylcyclohexa-2,5-diene-1,4-diylidene)dipropanedinitrile
CAS 138048-66-5C14H8N4
2,2'-(2-Dodecylcyclohexa-2,5-diene-1,4-diylidene)dipropanedinitrile chemical structure, C24H28N4, CAS 105314-21-4
2,2'-(2-Dodecylcyclohexa-2,5-diene-1,4-diylidene)dipropanedinitrile
CAS 105314-21-4C24H28N4
1,2,4,5-Tetrachloro-3,6-bis(dichloromethylidene)cyclohexa-1,4-diene chemical structure, C8Cl8, CAS 16955-42-3
1,2,4,5-Tetrachloro-3,6-bis(dichloromethylidene)cyclohexa-1,4-diene
CAS 16955-42-3C8Cl8
2-Fluoro-7,7,8,8-tetracyanoquinodimethane chemical structure, C12H3FN4, CAS 69857-37-0
2-Fluoro-7,7,8,8-tetracyanoquinodimethane
CAS 69857-37-0C12H3FN4
2,5-Bis(2-hydroxyethoxy)-7,7,8,8-tetracyanoquinodimethane chemical structure, C16H12N4O4, CAS 58268-29-4
2,5-Bis(2-hydroxyethoxy)-7,7,8,8-tetracyanoquinodimethane
CAS 58268-29-4C16H12N4O4
1-(3,6-Dimethylidenecyclohexa-1,4-dien-1-yl)ethanone chemical structure, C10H10O, CAS 85567-65-3
1-(3,6-Dimethylidenecyclohexa-1,4-dien-1-yl)ethanone
CAS 85567-65-3C10H10O
1-[4-(1-Hydroxyethylidene)cyclohexa-2,5-dien-1-ylidene]ethanol chemical structure, C10H12O2, CAS 180519-64-6
1-[4-(1-Hydroxyethylidene)cyclohexa-2,5-dien-1-ylidene]ethanol
CAS 180519-64-6C10H12O2
Hydroxy(4-methylidenecyclohexa-2,5-dien-1-ylidene)acetic acid chemical structure, C9H8O3, CAS 112088-60-5
Hydroxy(4-methylidenecyclohexa-2,5-dien-1-ylidene)acetic acid
CAS 112088-60-5C9H8O3
2-[4-(Cyanomethylidene)cyclohexa-2,5-dien-1-ylidene]acetonitrile chemical structure, C10H6N2, CAS 14544-92-4
2-[4-(Cyanomethylidene)cyclohexa-2,5-dien-1-ylidene]acetonitrile
CAS 14544-92-4C10H6N2