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Murcko scaffold

1,2,4,5-Tetraphenyl-1H-imidazole scaffold

10 chemicals on CompoundList share this ring system.

Rings
5
Scaffold atoms
29
Chemicals
10
With full pages
3
Scaffold SMILES

c1ccc(-c2nc(-c3ccccc3)n(-c3ccccc3)c2-c2ccccc2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1,2,4,5-Tetraphenyl-1H-imidazole page
Murcko scaffold c1ccc(-c2nc(-c3ccccc3)n(-c3ccccc3)c2-c2ccccc2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 10 of 10 chemicals

1,2,4,5-Tetraphenyl-1H-imidazole chemical structure, C27H20N2, CAS 13730-10-4
1,2,4,5-Tetraphenyl-1H-imidazole
CAS 13730-10-4C27H20N2
2-(4-Methoxyphenyl)-4,5-diphenyl-1-[4-(trifluoromethoxy)phenyl]-1H-imidazole chemical structure, C29H21F3N2O2, CAS 1022404-16-5
2-(4-Methoxyphenyl)-4,5-diphenyl-1-[4-(trifluoromethoxy)phenyl]-1H-imidazole
CAS 1022404-16-5C29H21F3N2O2
(4-(4,5-Diphenyl-2-(3,4,5-trimethoxyphenyl)imidazolyl)phenoxy)trifluoromethane chemical structure, C31H25F3N2O4, CAS 1022404-11-0
(4-(4,5-Diphenyl-2-(3,4,5-trimethoxyphenyl)imidazolyl)phenoxy)trifluoromethane
CAS 1022404-11-0C31H25F3N2O4
4-Methoxy-1-(2-(4-methoxyphenyl)-4,5-diphenylimidazolyl)benzene chemical structure, C29H24N2O2, CAS 21124-69-6
4-Methoxy-1-(2-(4-methoxyphenyl)-4,5-diphenylimidazolyl)benzene
CAS 21124-69-6C29H24N2O2
4-[1-(4-Methoxyphenyl)-4,5-diphenyl-1H-imidazol-2-yl]phenol chemical structure, C28H22N2O2, CAS 497061-20-8
4-[1-(4-Methoxyphenyl)-4,5-diphenyl-1H-imidazol-2-yl]phenol
CAS 497061-20-8C28H22N2O2
4-(4,5-Diphenyl-1-(4-(trifluoromethoxy)phenyl)imidazol-2-yl)phenol chemical structure, C28H19F3N2O2, CAS 497061-18-4
4-(4,5-Diphenyl-1-(4-(trifluoromethoxy)phenyl)imidazol-2-yl)phenol
CAS 497061-18-4C28H19F3N2O2
1-(4-Methylphenyl)-2,4,5-triphenyl-1H-imidazole chemical structure, C28H22N2, CAS 16112-36-0
1-(4-Methylphenyl)-2,4,5-triphenyl-1H-imidazole
CAS 16112-36-0C28H22N2
2-(2,4-Dimethoxyphenyl)-1-(4-methylphenyl)-4,5-diphenyl-1H-imidazole chemical structure, C30H26N2O2, CAS 853310-43-7
2-(2,4-Dimethoxyphenyl)-1-(4-methylphenyl)-4,5-diphenyl-1H-imidazole
CAS 853310-43-7C30H26N2O2
2-(4-Bromophenyl)-1-(4-methylphenyl)-4,5-diphenyl-1H-imidazole chemical structure, C28H21BrN2, CAS 853310-45-9
2-(4-Bromophenyl)-1-(4-methylphenyl)-4,5-diphenyl-1H-imidazole
CAS 853310-45-9C28H21BrN2
2,4,5-Triphenyl-1-(2,4,6-trimethylphenyl)-1H-imidazole chemical structure, C30H26N2, CAS 919281-72-4
2,4,5-Triphenyl-1-(2,4,6-trimethylphenyl)-1H-imidazole
CAS 919281-72-4C30H26N2