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Murcko scaffold

2-[4-(4-Phenylpiperazin-1-yl)butyl]-2,3-dihydro-1H-isoindole-1,3-dione scaffold

6 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
27
Chemicals
6
With full pages
3
Scaffold SMILES

O=C1c2ccccc2C(=O)N1CCCCN1CCN(c2ccccc2)CC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-[4-(4-Phenylpiperazin-1-yl)butyl]-2,3-dihydro-1H-isoindole-1,3-dione page
Murcko scaffold O=C1c2ccccc2C(=O)N1CCCCN1CCN(c2ccccc2)CC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 6 of 6 chemicals

Nan 190 chemical structure, C23H27N3O3, CAS 102392-05-2
Nan 190
CAS 102392-05-2C23H27N3O3
2-(4-(4-(2-Methoxyphenyl)-1-piperazinyl)butyl)-1H-isoindole-1,3(2H)-dione hydrobromide (1:1) chemical structure, C23H28BrN3O3, CAS 115338-32-4
2-(4-(4-(2-Methoxyphenyl)-1-piperazinyl)butyl)-1H-isoindole-1,3(2H)-dione hydrobromide (1:1)
CAS 115338-32-4C23H28BrN3O3
2-[4-(4-Phenylpiperazin-1-yl)butyl]-2,3-dihydro-1H-isoindole-1,3-dione chemical structure, C22H25N3O2, CAS 115338-24-4
2-[4-(4-Phenylpiperazin-1-yl)butyl]-2,3-dihydro-1H-isoindole-1,3-dione
CAS 115338-24-4C22H25N3O2
2-(4-(4-(2,3-Dichlorophenyl)piperazin-1-yl)butyl)isoindoline-1,3-dione chemical structure, C22H23Cl2N3O2, CAS 367275-36-3
2-(4-(4-(2,3-Dichlorophenyl)piperazin-1-yl)butyl)isoindoline-1,3-dione
CAS 367275-36-3C22H23Cl2N3O2
2-{4-[4-(4-Bromo-2-methoxyphenyl)piperazin-1-yl]butyl}-1H-isoindole-1,3(2H)-dione chemical structure, C23H26BrN3O3, CAS 506442-31-5
2-{4-[4-(4-Bromo-2-methoxyphenyl)piperazin-1-yl]butyl}-1H-isoindole-1,3(2H)-dione
CAS 506442-31-5C23H26BrN3O3
2-{4-[4-(2-Methoxyphenyl)piperazin-1-yl]butyl}-2,3-dihydro-1H-isoindole-1,3-dione hydrochloride chemical structure, C23H28ClN3O3, CAS 1215360-07-8
2-{4-[4-(2-Methoxyphenyl)piperazin-1-yl]butyl}-2,3-dihydro-1H-isoindole-1,3-dione hydrochloride
CAS 1215360-07-8C23H28ClN3O3