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Murcko scaffold

Ring system with 3 rings and 18 atoms

20 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
18
Chemicals
20
With full pages
11
Scaffold SMILES

O=c1ccc2cccc(CN3CCNCC3)c2o1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1ccc2cccc(CN3CCNCC3)c2o1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 20 of 20 chemicals

7-Hydroxy-8-{[4-(2-hydroxyethyl)piperazin-1-yl]methyl}-4-methyl-2H-chromen-2-one chemical structure, C17H22N2O4, CAS 294875-39-1
7-Hydroxy-8-{[4-(2-hydroxyethyl)piperazin-1-yl]methyl}-4-methyl-2H-chromen-2-one
CAS 294875-39-1C17H22N2O4
6-Chloro-8-[(4-ethylpiperazin-1-yl)methyl]-7-hydroxy-4-methylchromen-2-one chemical structure, C17H21ClN2O3, CAS 307535-52-0
6-Chloro-8-[(4-ethylpiperazin-1-yl)methyl]-7-hydroxy-4-methylchromen-2-one
CAS 307535-52-0C17H21ClN2O3
8-[(4-Ethylpiperazin-1-yl)methyl]-7-hydroxy-4-methyl-2H-chromen-2-one chemical structure, C17H22N2O3, CAS 347914-58-3
8-[(4-Ethylpiperazin-1-yl)methyl]-7-hydroxy-4-methyl-2H-chromen-2-one
CAS 347914-58-3C17H22N2O3
Coumarin, 6,7-dihydroxy-8-((4-(2-hydroxyethyl)-1-piperazinyl)methyl)-, dihydrochloride chemical structure, C16H22Cl2N2O5, CAS 94821-97-3
Coumarin, 6,7-dihydroxy-8-((4-(2-hydroxyethyl)-1-piperazinyl)methyl)-, dihydrochloride
CAS 94821-97-3C16H22Cl2N2O5
6-Chloro-7-hydroxy-4-methyl-8-[(4-methylpiperazin-1-yl)methyl]chromen-2-one chemical structure, C16H19ClN2O3, CAS 302551-62-8
6-Chloro-7-hydroxy-4-methyl-8-[(4-methylpiperazin-1-yl)methyl]chromen-2-one
CAS 302551-62-8C16H19ClN2O3
6-Chloro-7-hydroxy-3,4-dimethyl-8-[(4-methylpiperazin-1-yl)methyl]-2H-chromen-2-one chemical structure, C17H21ClN2O3, CAS 840511-98-0
6-Chloro-7-hydroxy-3,4-dimethyl-8-[(4-methylpiperazin-1-yl)methyl]-2H-chromen-2-one
CAS 840511-98-0C17H21ClN2O3
6-Chloro-7-hydroxy-8-[(4-methylpiperazin-1-yl)methyl]-4-propylchromen-2-one chemical structure, C18H23ClN2O3, CAS 840499-35-6
6-Chloro-7-hydroxy-8-[(4-methylpiperazin-1-yl)methyl]-4-propylchromen-2-one
CAS 840499-35-6C18H23ClN2O3
6-Chloro-4-ethyl-7-hydroxy-8-[(4-methylpiperazin-1-yl)methyl]chromen-2-one chemical structure, C17H21ClN2O3, CAS 843626-50-6
6-Chloro-4-ethyl-7-hydroxy-8-[(4-methylpiperazin-1-yl)methyl]chromen-2-one
CAS 843626-50-6C17H21ClN2O3
7-Hydroxy-4-methyl-8-[(4-methylpiperazin-1-yl)methyl]-2H-chromen-2-one chemical structure, C16H20N2O3, CAS 307535-36-0
7-Hydroxy-4-methyl-8-[(4-methylpiperazin-1-yl)methyl]-2H-chromen-2-one
CAS 307535-36-0C16H20N2O3
7-Hydroxy-8-[(4-methylpiperazin-1-yl)methyl]-4-propylchromen-2-one chemical structure, C18H24N2O3, CAS 389077-21-8
7-Hydroxy-8-[(4-methylpiperazin-1-yl)methyl]-4-propylchromen-2-one
CAS 389077-21-8C18H24N2O3
4-Ethyl-7-hydroxy-8-[(4-methylpiperazin-1-yl)methyl]-2H-chromen-2-one chemical structure, C17H22N2O3, CAS 858754-26-4
4-Ethyl-7-hydroxy-8-[(4-methylpiperazin-1-yl)methyl]-2H-chromen-2-one
CAS 858754-26-4C17H22N2O3
7-Hydroxy-3,4-dimethyl-8-[(4-methylpiperazin-1-yl)methyl]-2H-chromen-2-one chemical structure, C17H22N2O3, CAS 858761-63-4
7-Hydroxy-3,4-dimethyl-8-[(4-methylpiperazin-1-yl)methyl]-2H-chromen-2-one
CAS 858761-63-4C17H22N2O3
4-Butyl-7-hydroxy-8-[(4-methylpiperazin-1-yl)methyl]-2H-chromen-2-one chemical structure, C19H26N2O3, CAS 858744-33-9
4-Butyl-7-hydroxy-8-[(4-methylpiperazin-1-yl)methyl]-2H-chromen-2-one
CAS 858744-33-9C19H26N2O3
6-Chloro-7-hydroxy-4-methyl-8-[(4-methylpiperazine-1,4-diium-1-yl)methyl]chromen-2-one chemical structure, C16H21ClN2O3+2, CAS 6833-50-7
6-Chloro-7-hydroxy-4-methyl-8-[(4-methylpiperazine-1,4-diium-1-yl)methyl]chromen-2-one
CAS 6833-50-7C16H21ClN2O3+2
4-[(7-Hydroxy-2-oxo-4-propyl-2H-chromen-8-yl)methyl]-N,N-dimethylpiperazine-1-sulfonamide chemical structure, C19H27N3O5S, CAS 1401539-93-2
4-[(7-Hydroxy-2-oxo-4-propyl-2H-chromen-8-yl)methyl]-N,N-dimethylpiperazine-1-sulfonamide
CAS 1401539-93-2C19H27N3O5S
Methyl (8-{[4-(dimethylsulfamoyl)piperazin-1-yl]methyl}-7-hydroxy-4-methyl-2-oxo-2H-chromen-3-yl)acetate chemical structure, C20H27N3O7S, CAS 1435981-20-6
Methyl (8-{[4-(dimethylsulfamoyl)piperazin-1-yl]methyl}-7-hydroxy-4-methyl-2-oxo-2H-chromen-3-yl)acetate
CAS 1435981-20-6C20H27N3O7S
4-[(6-Chloro-7-hydroxy-2-oxo-4-propyl-2H-chromen-8-yl)methyl]-N,N-dimethylpiperazine-1-sulfonamide chemical structure, C19H26ClN3O5S, CAS 1401557-40-1
4-[(6-Chloro-7-hydroxy-2-oxo-4-propyl-2H-chromen-8-yl)methyl]-N,N-dimethylpiperazine-1-sulfonamide
CAS 1401557-40-1C19H26ClN3O5S
4-[(6-Chloro-4-ethyl-7-hydroxy-2-oxo-2H-chromen-8-yl)methyl]-N,N-dimethylpiperazine-1-sulfonamide chemical structure, C18H24ClN3O5S, CAS 1401539-84-1
4-[(6-Chloro-4-ethyl-7-hydroxy-2-oxo-2H-chromen-8-yl)methyl]-N,N-dimethylpiperazine-1-sulfonamide
CAS 1401539-84-1C18H24ClN3O5S
4-[(7-Hydroxy-3,4-dimethyl-2-oxo-2H-chromen-8-yl)methyl]-N,N-dimethylpiperazine-1-sulfonamide chemical structure, C18H25N3O5S, CAS 1401535-48-5
4-[(7-Hydroxy-3,4-dimethyl-2-oxo-2H-chromen-8-yl)methyl]-N,N-dimethylpiperazine-1-sulfonamide
CAS 1401535-48-5C18H25N3O5S
4-[(6-Chloro-7-hydroxy-3,4-dimethyl-2-oxo-2H-chromen-8-yl)methyl]-N,N-dimethylpiperazine-1-sulfonamide chemical structure, C18H24ClN3O5S, CAS 1435980-96-3
4-[(6-Chloro-7-hydroxy-3,4-dimethyl-2-oxo-2H-chromen-8-yl)methyl]-N,N-dimethylpiperazine-1-sulfonamide
CAS 1435980-96-3C18H24ClN3O5S