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Murcko scaffold

Ring system with 4 rings and 20 atoms

41 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
20
Chemicals
41
With full pages
8
Scaffold SMILES

O=C1C2=C(NC=CC2c2ccccc2)c2ccccc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1C2=C(NC=CC2c2ccccc2)c2ccccc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 41 of 41 chemicals

Ethyl 4-(4-hydroxyphenyl)-2-methyl-5-oxo-4,5-dihydro-1H-indeno[1,2-b]pyridine-3-carboxylate chemical structure, C22H19NO4, CAS 292066-08-1
Ethyl 4-(4-hydroxyphenyl)-2-methyl-5-oxo-4,5-dihydro-1H-indeno[1,2-b]pyridine-3-carboxylate
CAS 292066-08-1C22H19NO4
Ethyl 2-methyl-4-(4-nitrophenyl)-5-oxo-4,5-dihydro-1H-indeno[1,2-b]pyridine-3-carboxylate chemical structure, C22H18N2O5, CAS 35929-95-4
Ethyl 2-methyl-4-(4-nitrophenyl)-5-oxo-4,5-dihydro-1H-indeno[1,2-b]pyridine-3-carboxylate
CAS 35929-95-4C22H18N2O5
Ethyl 4-(4-methoxyphenyl)-2-methyl-5-oxo-4,5-dihydro-1H-indeno[1,2-b]pyridine-3-carboxylate chemical structure, C23H21NO4, CAS 90786-99-5
Ethyl 4-(4-methoxyphenyl)-2-methyl-5-oxo-4,5-dihydro-1H-indeno[1,2-b]pyridine-3-carboxylate
CAS 90786-99-5C23H21NO4
5H-Indeno[1,2-b]pyridin-5-one, 3-acetyl-1,4-dihydro-2-methyl-4-phenyl- chemical structure, C21H17NO2, CAS 26576-80-7
5H-Indeno[1,2-b]pyridin-5-one, 3-acetyl-1,4-dihydro-2-methyl-4-phenyl-
CAS 26576-80-7C21H17NO2
3-Acetyl-4-{4-nitrophenyl}-2-methyl-1,4-dihydro-5H-indeno[1,2-b]pyridin-5-one chemical structure, C21H16N2O4, CAS 35929-94-3
3-Acetyl-4-{4-nitrophenyl}-2-methyl-1,4-dihydro-5H-indeno[1,2-b]pyridin-5-one
CAS 35929-94-3C21H16N2O4
Ethyl 2-methyl-4-(2-nitrophenyl)-5-oxo-4,5-dihydro-1H-indeno[1,2-b]pyridine-3-carboxylate chemical structure, C22H18N2O5, CAS 81840-56-4
Ethyl 2-methyl-4-(2-nitrophenyl)-5-oxo-4,5-dihydro-1H-indeno[1,2-b]pyridine-3-carboxylate
CAS 81840-56-4C22H18N2O5
Ethyl 4-(3-methoxyphenyl)-2-methyl-5-oxo-4,5-dihydro-1H-indeno[1,2-b]pyridine-3-carboxylate chemical structure, C23H21NO4, CAS 332382-79-3
Ethyl 4-(3-methoxyphenyl)-2-methyl-5-oxo-4,5-dihydro-1H-indeno[1,2-b]pyridine-3-carboxylate
CAS 332382-79-3C23H21NO4
Ethyl 4-(3,4-dimethoxyphenyl)-2-methyl-5-oxo-4,5-dihydro-1H-indeno[1,2-b]pyridine-3-carboxylate chemical structure, C24H23NO5, CAS 332382-76-0
Ethyl 4-(3,4-dimethoxyphenyl)-2-methyl-5-oxo-4,5-dihydro-1H-indeno[1,2-b]pyridine-3-carboxylate
CAS 332382-76-0C24H23NO5
Methyl 4-(2-bromo-4,5-diethoxyphenyl)-2-methyl-5-oxo-4,5-dihydro-1H-indeno[1,2-b]pyridine-3-carboxylate chemical structure, C25H24BrNO5, CAS 425413-09-8
Methyl 4-(2-bromo-4,5-diethoxyphenyl)-2-methyl-5-oxo-4,5-dihydro-1H-indeno[1,2-b]pyridine-3-carboxylate
CAS 425413-09-8C25H24BrNO5
Methyl 4-(3-chloro-5-ethoxy-4-prop-2-enoxyphenyl)-2-methyl-5-oxo-1,4-dihydroindeno[1,2-b]pyridine-3-carboxylate chemical structure, C26H24ClNO5, CAS 425419-05-2
Methyl 4-(3-chloro-5-ethoxy-4-prop-2-enoxyphenyl)-2-methyl-5-oxo-1,4-dihydroindeno[1,2-b]pyridine-3-carboxylate
CAS 425419-05-2C26H24ClNO5
{2-[3-(Methoxycarbonyl)-2-methyl-5-oxo-4,5-dihydro-1H-indeno[1,2-b]pyridin-4-yl]phenoxy}acetic acid chemical structure, C23H19NO6, CAS 443126-29-2
{2-[3-(Methoxycarbonyl)-2-methyl-5-oxo-4,5-dihydro-1H-indeno[1,2-b]pyridin-4-yl]phenoxy}acetic acid
CAS 443126-29-2C23H19NO6
Methyl 2-methyl-4-(4-nitrophenyl)-5-oxo-4,5-dihydro-1H-indeno[1,2-b]pyridine-3-carboxylate chemical structure, C21H16N2O5, CAS 425619-75-6
Methyl 2-methyl-4-(4-nitrophenyl)-5-oxo-4,5-dihydro-1H-indeno[1,2-b]pyridine-3-carboxylate
CAS 425619-75-6C21H16N2O5
Ethyl 4-(3-chloro-5-methoxy-4-prop-2-ynoxyphenyl)-2-methyl-5-oxo-1,4-dihydroindeno[1,2-b]pyridine-3-carboxylate chemical structure, C26H22ClNO5, CAS 428832-62-6
Ethyl 4-(3-chloro-5-methoxy-4-prop-2-ynoxyphenyl)-2-methyl-5-oxo-1,4-dihydroindeno[1,2-b]pyridine-3-carboxylate
CAS 428832-62-6C26H22ClNO5
Ethyl 4-(2,3-dimethoxyphenyl)-2-methyl-5-oxo-4,5-dihydro-1H-indeno[1,2-b]pyridine-3-carboxylate chemical structure, C24H23NO5, CAS 77948-01-7
Ethyl 4-(2,3-dimethoxyphenyl)-2-methyl-5-oxo-4,5-dihydro-1H-indeno[1,2-b]pyridine-3-carboxylate
CAS 77948-01-7C24H23NO5
Ethyl 4-(4-ethylphenyl)-2-methyl-5-oxo-4,5-dihydro-1H-indeno[1,2-b]pyridine-3-carboxylate chemical structure, C24H23NO3, CAS 433318-79-7
Ethyl 4-(4-ethylphenyl)-2-methyl-5-oxo-4,5-dihydro-1H-indeno[1,2-b]pyridine-3-carboxylate
CAS 433318-79-7C24H23NO3
Ethyl 4-(3-chloro-4-methylphenyl)-2-methyl-5-oxo-4,5-dihydro-1H-indeno[1,2-b]pyridine-3-carboxylate chemical structure, C23H20ClNO3, CAS 433696-27-6
Ethyl 4-(3-chloro-4-methylphenyl)-2-methyl-5-oxo-4,5-dihydro-1H-indeno[1,2-b]pyridine-3-carboxylate
CAS 433696-27-6C23H20ClNO3
Ethyl 4-(3-fluorophenyl)-2-methyl-5-oxo-4,5-dihydro-1H-indeno[1,2-b]pyridine-3-carboxylate chemical structure, C22H18FNO3, CAS 442651-02-7
Ethyl 4-(3-fluorophenyl)-2-methyl-5-oxo-4,5-dihydro-1H-indeno[1,2-b]pyridine-3-carboxylate
CAS 442651-02-7C22H18FNO3
Methyl 4-(2,3-dichlorophenyl)-2-methyl-5-oxo-4,5-dihydro-1H-indeno[1,2-b]pyridine-3-carboxylate chemical structure, C21H15Cl2NO3, CAS 488854-65-5
Methyl 4-(2,3-dichlorophenyl)-2-methyl-5-oxo-4,5-dihydro-1H-indeno[1,2-b]pyridine-3-carboxylate
CAS 488854-65-5C21H15Cl2NO3
Methyl 4-(3-methoxyphenyl)-2-methyl-5-oxo-4,5-dihydro-1H-indeno[1,2-b]pyridine-3-carboxylate chemical structure, C22H19NO4, CAS 128691-52-1
Methyl 4-(3-methoxyphenyl)-2-methyl-5-oxo-4,5-dihydro-1H-indeno[1,2-b]pyridine-3-carboxylate
CAS 128691-52-1C22H19NO4
Ethyl 4-(2-bromophenyl)-2-methyl-5-oxo-4,5-dihydro-1H-indeno[1,2-b]pyridine-3-carboxylate chemical structure, C22H18BrNO3, CAS 522660-70-4
Ethyl 4-(2-bromophenyl)-2-methyl-5-oxo-4,5-dihydro-1H-indeno[1,2-b]pyridine-3-carboxylate
CAS 522660-70-4C22H18BrNO3
Methyl 4-(2-bromophenyl)-2-methyl-5-oxo-4,5-dihydro-1H-indeno[1,2-b]pyridine-3-carboxylate chemical structure, C21H16BrNO3, CAS 667431-49-4
Methyl 4-(2-bromophenyl)-2-methyl-5-oxo-4,5-dihydro-1H-indeno[1,2-b]pyridine-3-carboxylate
CAS 667431-49-4C21H16BrNO3
Ethyl 2-methyl-5-oxo-4-(4-(trifluoromethyl)phenyl)-4,5-dihydro-1H-indeno[1,2-b]pyridine-3-carboxylate chemical structure, C23H18F3NO3, CAS 689755-34-8
Ethyl 2-methyl-5-oxo-4-(4-(trifluoromethyl)phenyl)-4,5-dihydro-1H-indeno[1,2-b]pyridine-3-carboxylate
CAS 689755-34-8C23H18F3NO3
Methyl 4-(3-chloro-4-methoxyphenyl)-2-methyl-5-oxo-4,5-dihydro-1H-indeno[1,2-b]pyridine-3-carboxylate chemical structure, C22H18ClNO4, CAS 442568-87-8
Methyl 4-(3-chloro-4-methoxyphenyl)-2-methyl-5-oxo-4,5-dihydro-1H-indeno[1,2-b]pyridine-3-carboxylate
CAS 442568-87-8C22H18ClNO4
Methyl 4-(4-ethoxy-3-methoxyphenyl)-2-methyl-5-oxo-4,5-dihydro-1H-indeno[1,2-b]pyridine-3-carboxylate chemical structure, C24H23NO5, CAS 443289-43-8
Methyl 4-(4-ethoxy-3-methoxyphenyl)-2-methyl-5-oxo-4,5-dihydro-1H-indeno[1,2-b]pyridine-3-carboxylate
CAS 443289-43-8C24H23NO5