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Murcko scaffold

Ring system with 2 rings and 13 atoms

23 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
13
Chemicals
23
With full pages
1
Scaffold SMILES

O=c1ccn(C2CCOC2)c(=O)[nH]1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1ccn(C2CCOC2)c(=O)[nH]1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 23 of 23 chemicals

5-Fluoro-1-[4-hydroxy-2,5-bis(hydroxymethyl)oxolan-3-yl]pyrimidine-2,4-dione chemical structure, C10H13FN2O6, CAS 302790-83-6
5-Fluoro-1-[4-hydroxy-2,5-bis(hydroxymethyl)oxolan-3-yl]pyrimidine-2,4-dione
CAS 302790-83-6C10H13FN2O6
Bms 181165 chemical structure, C12H15BrN2O5, CAS 132523-59-2
Bms 181165
CAS 132523-59-2C12H15BrN2O5
BVisoDDU chemical structure, C11H13BrN2O4, CAS 479681-73-7
BVisoDDU
CAS 479681-73-7C11H13BrN2O4
1-[(3R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)oxolan-3-yl]-5-methylpyrimidine-2,4-dione chemical structure, C10H14N2O5, CAS 140623-93-4
1-[(3R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)oxolan-3-yl]-5-methylpyrimidine-2,4-dione
CAS 140623-93-4C10H14N2O5
1-[(2R,3R,4R,5S)-4-Hydroxy-2,5-bis(hydroxymethyl)oxolan-3-yl]-5-methylpyrimidine-2,4-dione chemical structure, C11H16N2O6, CAS 196596-88-0
1-[(2R,3R,4R,5S)-4-Hydroxy-2,5-bis(hydroxymethyl)oxolan-3-yl]-5-methylpyrimidine-2,4-dione
CAS 196596-88-0C11H16N2O6
6-Amino-5-nitroso-1-(tetrahydro-3-furanyl)-2,4(1H,3H)-pyrimidinedione chemical structure, C8H10N4O4, CAS 1055300-66-7
6-Amino-5-nitroso-1-(tetrahydro-3-furanyl)-2,4(1H,3H)-pyrimidinedione
CAS 1055300-66-7C8H10N4O4
5,6-Diamino-1-(tetrahydro-3-furanyl)-2,4(1H,3H)-pyrimidinedione chemical structure, C8H12N4O3, CAS 1055298-75-3
5,6-Diamino-1-(tetrahydro-3-furanyl)-2,4(1H,3H)-pyrimidinedione
CAS 1055298-75-3C8H12N4O3
6-Amino-1-(tetrahydro-3-furanyl)-2,4(1H,3H)-pyrimidinedione chemical structure, C8H11N3O3, CAS 1055299-79-0
6-Amino-1-(tetrahydro-3-furanyl)-2,4(1H,3H)-pyrimidinedione
CAS 1055299-79-0C8H11N3O3
1,4-Anhydro-3,5-dideoxy-3-(3,4-dihydro-2,4-dioxo-1 (2H)-pyrimidinyl)-D-xylo-hexitol chemical structure, C10H14N2O5, CAS 289665-57-2
1,4-Anhydro-3,5-dideoxy-3-(3,4-dihydro-2,4-dioxo-1 (2H)-pyrimidinyl)-D-xylo-hexitol
CAS 289665-57-2C10H14N2O5
1-[(2R,3R,4R)-4-Hydroxy-2-(2-hydroxyethyl)oxolan-3-yl]-5-methylpyrimidine-2,4-dione chemical structure, C11H16N2O5, CAS 289665-66-3
1-[(2R,3R,4R)-4-Hydroxy-2-(2-hydroxyethyl)oxolan-3-yl]-5-methylpyrimidine-2,4-dione
CAS 289665-66-3C11H16N2O5
1-[(3S,4S,5R)-4-Hydroxy-5-(2-hydroxyethyl)oxolan-3-yl]pyrimidine-2,4-dione chemical structure, C10H14N2O5, CAS 289665-56-1
1-[(3S,4S,5R)-4-Hydroxy-5-(2-hydroxyethyl)oxolan-3-yl]pyrimidine-2,4-dione
CAS 289665-56-1C10H14N2O5
1-[(3S,4S,5R)-4-Hydroxy-5-(2-hydroxyethyl)oxolan-3-yl]-5-methylpyrimidine-2,4-dione chemical structure, C11H16N2O5, CAS 289665-64-1
1-[(3S,4S,5R)-4-Hydroxy-5-(2-hydroxyethyl)oxolan-3-yl]-5-methylpyrimidine-2,4-dione
CAS 289665-64-1C11H16N2O5
1-[(2S,3S,4S,5R)-4-Hydroxy-2,5-bis(hydroxymethyl)oxolan-3-yl]pyrimidine-2,4-dione chemical structure, C10H14N2O6, CAS 302790-82-5
1-[(2S,3S,4S,5R)-4-Hydroxy-2,5-bis(hydroxymethyl)oxolan-3-yl]pyrimidine-2,4-dione
CAS 302790-82-5C10H14N2O6
2,5-Anhydro-3-deoxy-3-(3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)-D-iditol chemical structure, C10H14N2O6, CAS 302790-86-9
2,5-Anhydro-3-deoxy-3-(3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)-D-iditol
CAS 302790-86-9C10H14N2O6
1-[(2S,3S,4S,5R)-4-Hydroxy-5-(hydroxymethyl)-2-(prop-2-enoxymethyl)oxolan-3-yl]-5-methylpyrimidine-2,4-dione chemical structure, C14H20N2O6, CAS 473796-98-4
1-[(2S,3S,4S,5R)-4-Hydroxy-5-(hydroxymethyl)-2-(prop-2-enoxymethyl)oxolan-3-yl]-5-methylpyrimidine-2,4-dione
CAS 473796-98-4C14H20N2O6
1-[(2S,3R,4R,5S)-2-(Azidomethyl)-4-hydroxy-5-(hydroxymethyl)oxolan-3-yl]-5-methylpyrimidine-2,4-dione chemical structure, C11H15N5O5, CAS 944475-10-9
1-[(2S,3R,4R,5S)-2-(Azidomethyl)-4-hydroxy-5-(hydroxymethyl)oxolan-3-yl]-5-methylpyrimidine-2,4-dione
CAS 944475-10-9C11H15N5O5
1-[(2S,3R,4R,5S)-2-(Aminomethyl)-4-hydroxy-5-(hydroxymethyl)oxolan-3-yl]-5-methylpyrimidine-2,4-dione chemical structure, C11H17N3O5, CAS 944475-20-1
1-[(2S,3R,4R,5S)-2-(Aminomethyl)-4-hydroxy-5-(hydroxymethyl)oxolan-3-yl]-5-methylpyrimidine-2,4-dione
CAS 944475-20-1C11H17N3O5
1-[(2S,3S,4S,5R)-4-Hydroxy-2,5-bis(hydroxymethyl)oxolan-3-yl]-5-methylpyrimidine-2,4-dione chemical structure, C11H16N2O6, CAS 302790-81-4
1-[(2S,3S,4S,5R)-4-Hydroxy-2,5-bis(hydroxymethyl)oxolan-3-yl]-5-methylpyrimidine-2,4-dione
CAS 302790-81-4C11H16N2O6
5-Fluoro-1-[(2S,3S,4S,5R)-4-hydroxy-2,5-bis(hydroxymethyl)oxolan-3-yl]pyrimidine-2,4-dione chemical structure, C10H13FN2O6
5-Fluoro-1-[(2S,3S,4S,5R)-4-hydroxy-2,5-bis(hydroxymethyl)oxolan-3-yl]pyrimidine-2,4-dione
C10H13FN2O6
1-[(2R,3R,4R,5R)-5-(Dimethoxymethyl)-4-hydroxy-2-(prop-2-enoxymethyl)oxolan-3-yl]-5-methylpyrimidine-2,4-dione chemical structure, C16H24N2O7, CAS 473796-97-3
1-[(2R,3R,4R,5R)-5-(Dimethoxymethyl)-4-hydroxy-2-(prop-2-enoxymethyl)oxolan-3-yl]-5-methylpyrimidine-2,4-dione
CAS 473796-97-3C16H24N2O7
2,5-Anhydro-6-azido-4,6-dideoxy-4-(3,4-dihydro-5-methyl-2,4-dioxo-1(2H)-pyrimidinyl)-1-(dimethyl acetal)-L-mannose chemical structure, C13H19N5O6, CAS 900513-65-7
2,5-Anhydro-6-azido-4,6-dideoxy-4-(3,4-dihydro-5-methyl-2,4-dioxo-1(2H)-pyrimidinyl)-1-(dimethyl acetal)-L-mannose
CAS 900513-65-7C13H19N5O6
1-[(2S,3R,4R,5R)-4-Hydroxy-2,5-bis(hydroxymethyl)oxolan-3-yl]-5-methylpyrimidine-2,4-dione chemical structure, C11H16N2O6, CAS 302790-85-8
1-[(2S,3R,4R,5R)-4-Hydroxy-2,5-bis(hydroxymethyl)oxolan-3-yl]-5-methylpyrimidine-2,4-dione
CAS 302790-85-8C11H16N2O6
6-Chloro-3-methyl-1-(tetrahydrofuran-3-yl)pyrimidine-2,4(1H,3H)-dione chemical structure, C9H11ClN2O3, CAS 2091714-11-1
6-Chloro-3-methyl-1-(tetrahydrofuran-3-yl)pyrimidine-2,4(1H,3H)-dione
CAS 2091714-11-1C9H11ClN2O3