Murcko scaffold
Ring system with 2 rings and 12 atoms
7 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 12
- Chemicals
- 7
- With full pages
- 4
Scaffold SMILES
O=C1NC2CCCCC2NC1=O
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 7 of 7 chemicals
1,4-Dihydroxy-octahydro-quinoxaline-2,3-dione
CAS 286409-64-1C8H12N2O4
1,4-Dimethoxyoctahydroquinoxaline-2,3-dione
CAS 247564-26-7C10H16N2O4
1,4-Dihydroxy-4a-methyloctahydroquinoxaline-2,3-dione
CAS 247564-24-5C9H14N2O4
Octahydro-1,4-dimethoxy-4a-methyl-2,3-quinoxalinedione
CAS 247564-27-8C11H18N2O4
1,4-Bis(prop-2-en-1-yloxy)octahydroquinoxaline-2,3-dione
CAS 5537-33-7C14H20N2O4
Cis-5,6-tetramethylen-1,4-diallyloxypiperazine-2,3-dione
CAS 319427-18-4C14H20N2O4
2,3-Quinoxalinedione, octahydro-, (4aR,8aS)-
CAS 1152112-78-1C8H12N2O2
Related scaffolds
Same ring framework with different atoms or bond orders
c1ccc2ncccc2c12,226 chemicals
c1ccc2ccccc2c11,898 chemicals
O=c1ccc2ccccc2o1614 chemicals
c1ccc2c(c1)CCNC2607 chemicals
c1ccc2cnccc2c1569 chemicals
c1ccc2c(c1)CCCC2432 chemicals
c1ccc2c(c1)CCCN2384 chemicals
c1ccc2c(c1)CCCO2376 chemicals![Scaffold O=c1cc[nH]c2ccccc12](/scaffold/PMZDQRJGMBOQBF-UHFFFAOYSA-N/structure.svg)
O=c1cc[nH]c2ccccc12373 chemicals![Scaffold O=c1ccc2ccccc2[nH]1](/scaffold/LISFMEBWQUVKPJ-UHFFFAOYSA-N/structure.svg)
O=c1ccc2ccccc2[nH]1365 chemicals
c1ccc2ncncc2c1315 chemicals
c1ccc2c(c1)OCCO2299 chemicals