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Murcko scaffold

Ring system with 3 rings and 25 atoms

18 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
25
Chemicals
18
With full pages
15
Scaffold SMILES

O=C(CNC(=O)c1ccccc1)NN=Cc1cccc2ccccc12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CNC(=O)c1ccccc1)NN=Cc1cccc2ccccc12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 18 of 18 chemicals

3,4-Dimethoxy-N-(2-(2-(1-naphthylmethylene)hydrazino)-2-oxoethyl)benzamide chemical structure, C22H21N3O4, CAS 339005-10-6
3,4-Dimethoxy-N-(2-(2-(1-naphthylmethylene)hydrazino)-2-oxoethyl)benzamide
CAS 339005-10-6C22H21N3O4
4-Fluoro-N-(2-(2-(1-naphthylmethylene)hydrazino)-2-oxoethyl)benzamide chemical structure, C20H16FN3O2, CAS 769142-60-1
4-Fluoro-N-(2-(2-(1-naphthylmethylene)hydrazino)-2-oxoethyl)benzamide
CAS 769142-60-1C20H16FN3O2
N-(2-(2-(1-Naphthylmethylene)hydrazino)-2-oxoethyl)-4-propoxybenzamide chemical structure, C23H23N3O3, CAS 769143-18-2
N-(2-(2-(1-Naphthylmethylene)hydrazino)-2-oxoethyl)-4-propoxybenzamide
CAS 769143-18-2C23H23N3O3
3-Bromo-N-(2-(2-(1-naphthylmethylene)hydrazino)-2-oxoethyl)benzamide chemical structure, C20H16BrN3O2, CAS 769142-75-8
3-Bromo-N-(2-(2-(1-naphthylmethylene)hydrazino)-2-oxoethyl)benzamide
CAS 769142-75-8C20H16BrN3O2
2-Iodo-N-(2-(2-(1-naphthylmethylene)hydrazino)-2-oxoethyl)benzamide chemical structure, C20H16IN3O2, CAS 767338-74-9
2-Iodo-N-(2-(2-(1-naphthylmethylene)hydrazino)-2-oxoethyl)benzamide
CAS 767338-74-9C20H16IN3O2
4-Methyl-N-(2-(2-(1-naphthylmethylene)hydrazino)-2-oxoethyl)benzamide chemical structure, C21H19N3O2, CAS 767335-66-0
4-Methyl-N-(2-(2-(1-naphthylmethylene)hydrazino)-2-oxoethyl)benzamide
CAS 767335-66-0C21H19N3O2
2-Methyl-N-(2-(2-(1-naphthylmethylene)hydrazino)-2-oxoethyl)benzamide chemical structure, C21H19N3O2, CAS 444648-82-2
2-Methyl-N-(2-(2-(1-naphthylmethylene)hydrazino)-2-oxoethyl)benzamide
CAS 444648-82-2C21H19N3O2
4-Methoxy-N-{2-[(2E)-2-(1-naphthylmethylene)hydrazino]-2-oxoethyl}benzamide chemical structure, C21H19N3O3, CAS 767334-17-8
4-Methoxy-N-{2-[(2E)-2-(1-naphthylmethylene)hydrazino]-2-oxoethyl}benzamide
CAS 767334-17-8C21H19N3O3
N-(2-(2-((2-HO-1-Naphthyl)methylene)hydrazino)-2-oxoethyl)-4-methylbenzamide chemical structure, C21H19N3O3, CAS 443991-86-4
N-(2-(2-((2-HO-1-Naphthyl)methylene)hydrazino)-2-oxoethyl)-4-methylbenzamide
CAS 443991-86-4C21H19N3O3
4-Ethoxy-N-(2-(2-((2-HO-1-naphthyl)methylene)hydrazino)-2-oxoethyl)benzamide chemical structure, C22H21N3O4, CAS 767314-07-8
4-Ethoxy-N-(2-(2-((2-HO-1-naphthyl)methylene)hydrazino)-2-oxoethyl)benzamide
CAS 767314-07-8C22H21N3O4
N-(2-(2-((2-HO-1-Naphthyl)methylene)hydrazino)-2-oxoethyl)-4-propoxybenzamide chemical structure, C23H23N3O4, CAS 769149-53-3
N-(2-(2-((2-HO-1-Naphthyl)methylene)hydrazino)-2-oxoethyl)-4-propoxybenzamide
CAS 769149-53-3C23H23N3O4
N-(2-(2-((2-HO-1-Naphthyl)methylene)hydrazino)-2-oxoethyl)3,4-dimethoxybenzamide chemical structure, C22H21N3O5, CAS 339572-27-9
N-(2-(2-((2-HO-1-Naphthyl)methylene)hydrazino)-2-oxoethyl)3,4-dimethoxybenzamide
CAS 339572-27-9C22H21N3O5
N-(2-{(2E)-2-[(2-hydroxy-1-naphthyl)methylene]hydrazino}-2-oxoethyl)-4-methoxybenzamide chemical structure, C21H19N3O4, CAS 769156-87-8
N-(2-{(2E)-2-[(2-hydroxy-1-naphthyl)methylene]hydrazino}-2-oxoethyl)-4-methoxybenzamide
CAS 769156-87-8C21H19N3O4
N-(2-(2-((2-HO-1-Naphthyl)methylene)hydrazino)-2-oxoethyl)-2-methylbenzamide chemical structure, C21H19N3O3, CAS 455325-04-9
N-(2-(2-((2-HO-1-Naphthyl)methylene)hydrazino)-2-oxoethyl)-2-methylbenzamide
CAS 455325-04-9C21H19N3O3
4-F-N-(2-(2-((2-Hydroxy-1-naphthyl)methylene)hydrazino)-2-oxoethyl)benzamide chemical structure, C20H16FN3O3, CAS 765274-46-2
4-F-N-(2-(2-((2-Hydroxy-1-naphthyl)methylene)hydrazino)-2-oxoethyl)benzamide
CAS 765274-46-2C20H16FN3O3
3,4-Dichloro-N-(2-(2-((2-HO-1-naphthyl)methylene)hydrazino)-2-oxoethyl)benzamide chemical structure, C20H15Cl2N3O3, CAS 767313-86-0
3,4-Dichloro-N-(2-(2-((2-HO-1-naphthyl)methylene)hydrazino)-2-oxoethyl)benzamide
CAS 767313-86-0C20H15Cl2N3O3
3-Bromo-N-(2-(2-((2-hydroxy-1-naphthyl)methylene)hydrazino)-2-oxoethyl)benzamide chemical structure, C20H16BrN3O3, CAS 765303-48-8
3-Bromo-N-(2-(2-((2-hydroxy-1-naphthyl)methylene)hydrazino)-2-oxoethyl)benzamide
CAS 765303-48-8C20H16BrN3O3
N-(4-Methylbenzoyl)-L-valine 2-[(2-butoxy-1-naphthalenyl)methylene]hydrazide chemical structure, C28H33N3O3, CAS 1031266-45-1
N-(4-Methylbenzoyl)-L-valine 2-[(2-butoxy-1-naphthalenyl)methylene]hydrazide
CAS 1031266-45-1C28H33N3O3