Murcko scaffold
1-(Hexahydro-1H-azepin-1-yl)-3-(phenyl sulfonyl)urea scaffold
8 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 20
- Chemicals
- 8
- With full pages
- 2
Scaffold SMILES
O=C(NN1CCCCCC1)NS(=O)(=O)c1ccccc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 8 of 8 chemicals
Tolazamide
CAS 1156-19-0C14H21N3O3S
1-(Hexahydro-1H-azepin-1-yl)-3-(phenyl sulfonyl)urea
CAS 1443-97-6C13H19N3O3S
1-(p-Acetylphenylsulfonyl)-3-(hexahydro-1H-azepin-1-yl)urea
CAS 3168-04-5C15H21N3O4S
Glypinamide
CAS 1228-19-9C13H18ClN3O3S
4-Hydroxytolazamide
CAS 67084-66-6C14H21N3O4S
Tolazamide-d7
CAS 1794811-72-5C14H21N3O3S
4-Demethyl-4-carboxy tolazamide
CAS 40604-38-4C14H19N3O5S
4-Demethyl-4-(hydroxymethyl)tolazamide
CAS 67084-65-5C14H21N3O4S