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Murcko scaffold

2-Phenoxy-N-(4-(N-(thiazol-2-yl)sulfamoyl)phenyl)acetamide scaffold

39 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
26
Chemicals
39
With full pages
9
Scaffold SMILES

O=C(COc1ccccc1)Nc1ccc(S(=O)(=O)Nc2nccs2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-Phenoxy-N-(4-(N-(thiazol-2-yl)sulfamoyl)phenyl)acetamide page
Murcko scaffold O=C(COc1ccccc1)Nc1ccc(S(=O)(=O)Nc2nccs2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 39 of 39 chemicals

Acetamide, 2-(4-chlorophenoxy)-N-(4-((2-thiazolylamino)sulfonyl)phenyl)- chemical structure, C17H14ClN3O4S2, CAS 58590-35-5
Acetamide, 2-(4-chlorophenoxy)-N-(4-((2-thiazolylamino)sulfonyl)phenyl)-
CAS 58590-35-5C17H14ClN3O4S2
2-(2,3-Dimethylphenoxy)-N-[4-(1,3-thiazol-2-ylsulfamoyl)phenyl]acetamide chemical structure, C19H19N3O4S2, CAS 303117-11-5
2-(2,3-Dimethylphenoxy)-N-[4-(1,3-thiazol-2-ylsulfamoyl)phenyl]acetamide
CAS 303117-11-5C19H19N3O4S2
2-Phenoxy-N-(4-(N-(thiazol-2-yl)sulfamoyl)phenyl)acetamide chemical structure, C17H15N3O4S2, CAS 58590-31-1
2-Phenoxy-N-(4-(N-(thiazol-2-yl)sulfamoyl)phenyl)acetamide
CAS 58590-31-1C17H15N3O4S2
2-(2,4-Dichlorophenoxy)-N-{4-[(1,3-thiazol-2-ylamino)sulfonyl]phenyl}acetamide chemical structure, C17H13Cl2N3O4S2, CAS 332414-53-6
2-(2,4-Dichlorophenoxy)-N-{4-[(1,3-thiazol-2-ylamino)sulfonyl]phenyl}acetamide
CAS 332414-53-6C17H13Cl2N3O4S2
2-(2-Bromo-4-methylphenoxy)-N-{4-[(1,3-thiazol-2-ylamino)sulfonyl]phenyl}acetamide chemical structure, C18H16BrN3O4S2, CAS 432019-99-3
2-(2-Bromo-4-methylphenoxy)-N-{4-[(1,3-thiazol-2-ylamino)sulfonyl]phenyl}acetamide
CAS 432019-99-3C18H16BrN3O4S2
2-(4-Bromo-3-methylphenoxy)-N-[4-(1,3-thiazol-2-ylsulfamoyl)phenyl]acetamide chemical structure, C18H16BrN3O4S2, CAS 443319-50-4
2-(4-Bromo-3-methylphenoxy)-N-[4-(1,3-thiazol-2-ylsulfamoyl)phenyl]acetamide
CAS 443319-50-4C18H16BrN3O4S2
2-(2-Bromo-4-ethylphenoxy)-N-(4-(N-(thiazol-2-yl)sulfamoyl)phenyl)acetamide chemical structure, C19H18BrN3O4S2, CAS 590400-56-9
2-(2-Bromo-4-ethylphenoxy)-N-(4-(N-(thiazol-2-yl)sulfamoyl)phenyl)acetamide
CAS 590400-56-9C19H18BrN3O4S2
2-(2,5-Dimethylphenoxy)-N-{4-[(1,3-thiazol-2-ylamino)sulfonyl]phenyl}acetamide chemical structure, C19H19N3O4S2, CAS 315713-43-0
2-(2,5-Dimethylphenoxy)-N-{4-[(1,3-thiazol-2-ylamino)sulfonyl]phenyl}acetamide
CAS 315713-43-0C19H19N3O4S2
2-(4-Isopropylphenoxy)-N-{4-[(1,3-thiazol-2-ylamino)sulfonyl]phenyl}acetamide chemical structure, C20H21N3O4S2, CAS 651018-73-4
2-(4-Isopropylphenoxy)-N-{4-[(1,3-thiazol-2-ylamino)sulfonyl]phenyl}acetamide
CAS 651018-73-4C20H21N3O4S2
2-(2-Methoxy-phenoxy)-N-[4-(thiazol-2-ylsulfamoyl)-phenyl]-acetamide chemical structure, C18H17N3O5S2, CAS 374548-97-7
2-(2-Methoxy-phenoxy)-N-[4-(thiazol-2-ylsulfamoyl)-phenyl]-acetamide
CAS 374548-97-7C18H17N3O5S2
2-(4-tert-Butylphenoxy)-N-[4-(1,3-thiazol-2-ylsulfamoyl)phenyl]acetamide chemical structure, C21H23N3O4S2, CAS 445409-28-9
2-(4-tert-Butylphenoxy)-N-[4-(1,3-thiazol-2-ylsulfamoyl)phenyl]acetamide
CAS 445409-28-9C21H23N3O4S2
2-(4-Ethylphenoxy)-N-(4-(N-(thiazol-2-yl)sulfamoyl)phenyl)acetamide chemical structure, C19H19N3O4S2, CAS 496011-12-2
2-(4-Ethylphenoxy)-N-(4-(N-(thiazol-2-yl)sulfamoyl)phenyl)acetamide
CAS 496011-12-2C19H19N3O4S2
2-(4-Chloro-3-methylphenoxy)-N-[4-(1,3-thiazol-2-ylsulfamoyl)phenyl]acetamide chemical structure, C18H16ClN3O4S2, CAS 650614-70-3
2-(4-Chloro-3-methylphenoxy)-N-[4-(1,3-thiazol-2-ylsulfamoyl)phenyl]acetamide
CAS 650614-70-3C18H16ClN3O4S2
2-(2-Isopropylphenoxy)-N-{4-[(1,3-thiazol-2-ylamino)sulfonyl]phenyl}acetamide chemical structure, C20H21N3O4S2, CAS 606923-54-0
2-(2-Isopropylphenoxy)-N-{4-[(1,3-thiazol-2-ylamino)sulfonyl]phenyl}acetamide
CAS 606923-54-0C20H21N3O4S2
2-(2,4-Dimethylphenoxy)-N-[4-(1,3-thiazol-2-ylsulfamoyl)phenyl]acetamide chemical structure, C19H19N3O4S2, CAS 448241-44-9
2-(2,4-Dimethylphenoxy)-N-[4-(1,3-thiazol-2-ylsulfamoyl)phenyl]acetamide
CAS 448241-44-9C19H19N3O4S2
2-(2-Methylphenoxy)-N-[4-(1,3-thiazol-2-ylsulfamoyl)phenyl]acetamide chemical structure, C18H17N3O4S2, CAS 372497-85-3
2-(2-Methylphenoxy)-N-[4-(1,3-thiazol-2-ylsulfamoyl)phenyl]acetamide
CAS 372497-85-3C18H17N3O4S2
2-(4-Methylphenoxy)-N-[4-(1,3-thiazol-2-ylsulfamoyl)phenyl]acetamide chemical structure, C18H17N3O4S2, CAS 313515-93-4
2-(4-Methylphenoxy)-N-[4-(1,3-thiazol-2-ylsulfamoyl)phenyl]acetamide
CAS 313515-93-4C18H17N3O4S2
2-(4-Methoxyphenoxy)-N-[4-(1,3-thiazol-2-ylsulfamoyl)phenyl]acetamide chemical structure, C18H17N3O5S2, CAS 372500-88-4
2-(4-Methoxyphenoxy)-N-[4-(1,3-thiazol-2-ylsulfamoyl)phenyl]acetamide
CAS 372500-88-4C18H17N3O5S2
2-(2-Fluorophenoxy)-N-[4-(1,3-thiazol-2-ylsulfamoyl)phenyl]acetamide chemical structure, C17H14FN3O4S2, CAS 373371-48-3
2-(2-Fluorophenoxy)-N-[4-(1,3-thiazol-2-ylsulfamoyl)phenyl]acetamide
CAS 373371-48-3C17H14FN3O4S2
2-(4-Fluorophenoxy)-N-[4-(1,3-thiazol-2-ylsulfamoyl)phenyl]acetamide chemical structure, C17H14FN3O4S2, CAS 335421-15-3
2-(4-Fluorophenoxy)-N-[4-(1,3-thiazol-2-ylsulfamoyl)phenyl]acetamide
CAS 335421-15-3C17H14FN3O4S2
2-(4-Bromophenoxy)-N-[4-(1,3-thiazol-2-ylsulfamoyl)phenyl]acetamide chemical structure, C17H14BrN3O4S2, CAS 374101-18-5
2-(4-Bromophenoxy)-N-[4-(1,3-thiazol-2-ylsulfamoyl)phenyl]acetamide
CAS 374101-18-5C17H14BrN3O4S2
2-(2-Chlorophenoxy)-N-[4-(1,3-thiazol-2-ylsulfamoyl)phenyl]acetamide chemical structure, C17H14ClN3O4S2, CAS 433313-26-9
2-(2-Chlorophenoxy)-N-[4-(1,3-thiazol-2-ylsulfamoyl)phenyl]acetamide
CAS 433313-26-9C17H14ClN3O4S2
2-(2-Bromo-phenoxy)-N-[4-(thiazol-2-ylsulfamoyl)-phenyl]-acetamide chemical structure, C17H14BrN3O4S2, CAS 307537-63-9
2-(2-Bromo-phenoxy)-N-[4-(thiazol-2-ylsulfamoyl)-phenyl]-acetamide
CAS 307537-63-9C17H14BrN3O4S2
2-(4-Bromo-2-(tert-butyl)phenoxy)-N-(4-(N-(thiazol-2-yl)sulfamoyl)phenyl)acetamide chemical structure, C21H22BrN3O4S2, CAS 305375-62-6
2-(4-Bromo-2-(tert-butyl)phenoxy)-N-(4-(N-(thiazol-2-yl)sulfamoyl)phenyl)acetamide
CAS 305375-62-6C21H22BrN3O4S2