Murcko scaffold
Ring system with 3 rings and 26 atoms
18 chemicals on CompoundList share this ring system.
- Rings
- 3
- Scaffold atoms
- 26
- Chemicals
- 18
- With full pages
- 5
Scaffold SMILES
O=C(NC(=S)Nc1ccc(NC(=O)c2cccs2)cc1)c1ccccc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 18 of 18 chemicals
![N-[4-[(3-Methylbenzoyl)carbamothioylamino]phenyl]thiophene-2-carboxamide chemical structure, C20H17N3O2S2, CAS 426220-74-8](/s/HAIZDLGKMVIVHG-UHFFFAOYSA-N.svg)
N-[4-[(3-Methylbenzoyl)carbamothioylamino]phenyl]thiophene-2-carboxamide
CAS 426220-74-8C20H17N3O2S2
![N-[4-[(3-Ethoxybenzoyl)carbamothioylamino]phenyl]thiophene-2-carboxamide chemical structure, C21H19N3O3S2, CAS 428481-79-2](/s/AUMUMYYQPSZANO-UHFFFAOYSA-N.svg)
N-[4-[(3-Ethoxybenzoyl)carbamothioylamino]phenyl]thiophene-2-carboxamide
CAS 428481-79-2C21H19N3O3S2
![N-[2-Methoxy-4-[(2-methylbenzoyl)carbamothioylamino]phenyl]thiophene-2-carboxamide chemical structure, C21H19N3O3S2, CAS 431997-91-0](/s/UPHDMXMTXXQCMA-UHFFFAOYSA-N.svg)
N-[2-Methoxy-4-[(2-methylbenzoyl)carbamothioylamino]phenyl]thiophene-2-carboxamide
CAS 431997-91-0C21H19N3O3S2
![N-[4-[(2-Methylbenzoyl)carbamothioylamino]phenyl]thiophene-2-carboxamide chemical structure, C20H17N3O2S2, CAS 425683-50-7](/s/JUHFVJXJKVBLPP-UHFFFAOYSA-N.svg)
N-[4-[(2-Methylbenzoyl)carbamothioylamino]phenyl]thiophene-2-carboxamide
CAS 425683-50-7C20H17N3O2S2
![N-[4-[(3-Methoxybenzoyl)carbamothioylamino]phenyl]thiophene-2-carboxamide chemical structure, C20H17N3O3S2, CAS 428464-30-6](/s/IOXVOQAQHOFBRW-UHFFFAOYSA-N.svg)
N-[4-[(3-Methoxybenzoyl)carbamothioylamino]phenyl]thiophene-2-carboxamide
CAS 428464-30-6C20H17N3O3S2
![N-[4-[(2-Methoxybenzoyl)carbamothioylamino]phenyl]thiophene-2-carboxamide chemical structure, C20H17N3O3S2, CAS 428483-26-5](/s/NUZDAZCTZRICGP-UHFFFAOYSA-N.svg)
N-[4-[(2-Methoxybenzoyl)carbamothioylamino]phenyl]thiophene-2-carboxamide
CAS 428483-26-5C20H17N3O3S2
![N-[4-[(3,5-Dimethoxybenzoyl)carbamothioylamino]phenyl]thiophene-2-carboxamide chemical structure, C21H19N3O4S2, CAS 429648-18-0](/s/XGFJTWGURKAQHI-UHFFFAOYSA-N.svg)
N-[4-[(3,5-Dimethoxybenzoyl)carbamothioylamino]phenyl]thiophene-2-carboxamide
CAS 429648-18-0C21H19N3O4S2
![N-[4-[(3-Chloro-4-methoxybenzoyl)carbamothioylamino]phenyl]thiophene-2-carboxamide chemical structure, C20H16ClN3O3S2, CAS 378755-05-6](/s/XITQFWATCXZMAJ-UHFFFAOYSA-N.svg)
N-[4-[(3-Chloro-4-methoxybenzoyl)carbamothioylamino]phenyl]thiophene-2-carboxamide
CAS 378755-05-6C20H16ClN3O3S2
![N-[4-[(2-Fluorobenzoyl)carbamothioylamino]phenyl]thiophene-2-carboxamide chemical structure, C19H14FN3O2S2, CAS 380575-84-8](/s/KKXXDXPNGQYDTA-UHFFFAOYSA-N.svg)
N-[4-[(2-Fluorobenzoyl)carbamothioylamino]phenyl]thiophene-2-carboxamide
CAS 380575-84-8C19H14FN3O2S2
![N-[4-[(3-Fluorobenzoyl)carbamothioylamino]phenyl]thiophene-2-carboxamide chemical structure, C19H14FN3O2S2, CAS 425664-95-5](/s/INQNVUHXZHBACH-UHFFFAOYSA-N.svg)
N-[4-[(3-Fluorobenzoyl)carbamothioylamino]phenyl]thiophene-2-carboxamide
CAS 425664-95-5C19H14FN3O2S2
![N-[4-({[(2-Bromophenyl)carbonyl]carbamothioyl}amino)phenyl]thiophene-2-carboxamide chemical structure, C19H14BrN3O2S2, CAS 6413-04-3](/s/GPYUHOKTUFGOMW-UHFFFAOYSA-N.svg)
N-[4-({[(2-Bromophenyl)carbonyl]carbamothioyl}amino)phenyl]thiophene-2-carboxamide
CAS 6413-04-3C19H14BrN3O2S2
![N-[4-[(4-Butoxybenzoyl)carbamothioylamino]phenyl]thiophene-2-carboxamide chemical structure, C23H23N3O3S2, CAS 428465-38-7](/s/CSTDBMFFITUUMG-UHFFFAOYSA-N.svg)
N-[4-[(4-Butoxybenzoyl)carbamothioylamino]phenyl]thiophene-2-carboxamide
CAS 428465-38-7C23H23N3O3S2
![N-[4-[(2-Methoxy-3-methylbenzoyl)carbamothioylamino]phenyl]thiophene-2-carboxamide chemical structure, C21H19N3O3S2, CAS 833432-04-5](/s/YKCMZGFJFHAMFZ-UHFFFAOYSA-N.svg)
N-[4-[(2-Methoxy-3-methylbenzoyl)carbamothioylamino]phenyl]thiophene-2-carboxamide
CAS 833432-04-5C21H19N3O3S2
![N-[4-[(4-Ethoxy-3-nitrobenzoyl)carbamothioylamino]phenyl]thiophene-2-carboxamide chemical structure, C21H18N4O5S2, CAS 428482-84-2](/s/NDMHARLTSRRJFU-UHFFFAOYSA-N.svg)
N-[4-[(4-Ethoxy-3-nitrobenzoyl)carbamothioylamino]phenyl]thiophene-2-carboxamide
CAS 428482-84-2C21H18N4O5S2
![N-[4-[(2-Methyl-3-nitrobenzoyl)carbamothioylamino]phenyl]thiophene-2-carboxamide chemical structure, C20H16N4O4S2, CAS 429647-37-0](/s/BBDXZZCQFHWTOZ-UHFFFAOYSA-N.svg)
N-[4-[(2-Methyl-3-nitrobenzoyl)carbamothioylamino]phenyl]thiophene-2-carboxamide
CAS 429647-37-0C20H16N4O4S2
![N-[4-[(4-Methyl-3-nitrobenzoyl)carbamothioylamino]phenyl]thiophene-2-carboxamide chemical structure, C20H16N4O4S2, CAS 428484-88-2](/s/SVCBSPWTFVYCOI-UHFFFAOYSA-N.svg)
N-[4-[(4-Methyl-3-nitrobenzoyl)carbamothioylamino]phenyl]thiophene-2-carboxamide
CAS 428484-88-2C20H16N4O4S2
![N-[4-[(4-Methoxy-3-nitrobenzoyl)carbamothioylamino]phenyl]thiophene-2-carboxamide chemical structure, C20H16N4O5S2, CAS 364612-07-7](/s/CLIDSODGFONKCL-UHFFFAOYSA-N.svg)
N-[4-[(4-Methoxy-3-nitrobenzoyl)carbamothioylamino]phenyl]thiophene-2-carboxamide
CAS 364612-07-7C20H16N4O5S2
![N-[4-[(3-Nitrobenzoyl)carbamothioylamino]phenyl]thiophene-2-carboxamide chemical structure, C19H14N4O4S2, CAS 428467-81-6](/s/MBUXWMJYTZBKIT-UHFFFAOYSA-N.svg)
N-[4-[(3-Nitrobenzoyl)carbamothioylamino]phenyl]thiophene-2-carboxamide
CAS 428467-81-6C19H14N4O4S2
Related scaffolds
Same ring framework with different atoms or bond orders
O=C(COc1ccccc1)Nc1ccc(NC(=O)c2ccco2)cc110 chemicals
O=C(COc1ccccc1)Nc1ccc(S(=O)(=O)Nc2nccs2)cc19 chemicals
O=C(COc1ccccc1)Nc1ccc(S(=O)(=O)Nc2ccno2)cc19 chemicals![Scaffold O=C(CSc1ncc(NC(=O)c2cccs2)c(=O)[nH]1)Nc1ccccc1](/scaffold/AXQDYISHCOFPNU-UHFFFAOYSA-N/structure.svg)
O=C(CSc1ncc(NC(=O)c2cccs2)c(=O)[nH]1)Nc1ccccc16 chemicals
O=C(COc1ccccc1)Nc1ccc(S(=O)(=O)Nc2ccon2)cc16 chemicals
O=C(NC(=S)Nc1ccc(NC(=O)c2ccco2)cc1)c1ccccc16 chemicals
O=C(C=Cc1ccccc1)Nc1ccc(S(=O)(=O)Nc2ccno2)cc14 chemicals
O=C(CS(=O)(=O)c1ccccc1)Nc1ccc(S(=O)(=O)Nc2ccno2)cc12 chemicals
O=C(C=Cc1ccccc1)Nc1ccc(NC(=O)c2ccco2)cc12 chemicals
O=C(NN=Cc1ccc(OC(=O)c2cccs2)cc1)c1ccccc12 chemicals
O=C(CCc1ccccc1)Nc1ccc(S(=O)(=O)Nc2nccs2)cc12 chemicals
O=C(NN=Cc1ccc(OCc2cncs2)cc1)c1ccncc12 chemicals