Murcko scaffold
Ring system with 4 rings and 21 atoms
11 chemicals on CompoundList share this ring system.
- Rings
- 4
- Scaffold atoms
- 21
- Chemicals
- 11
- With full pages
- 6
Scaffold SMILES
S=c1[nH]nc(C2CC2c2ccccc2)n1-c1ccccc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
![Murcko scaffold S=c1[nH]nc(C2CC2c2ccccc2)n1-c1ccccc1](/scaffold/NZNVJIVQSTURJS-UHFFFAOYSA-N/structure.svg)
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 11 of 11 chemicals
4-(3-Chloro-4-fluorophenyl)-5-(2-p-tolylcyclopropyl)-4H-1,2,4-triazole-3-thiol
CAS 512825-06-8C18H15ClFN3S
![4-(3-Methylphenyl)-3-[2-(4-methylphenyl)cyclopropyl]-1H-1,2,4-triazole-5-thione chemical structure, C19H19N3S, CAS 512825-53-5](/s/VEORGKHHPILGTA-UHFFFAOYSA-N.svg)
4-(3-Methylphenyl)-3-[2-(4-methylphenyl)cyclopropyl]-1H-1,2,4-triazole-5-thione
CAS 512825-53-5C19H19N3S
![4-(4-Methoxyphenyl)-3-[2-(4-methylphenyl)cyclopropyl]-1H-1,2,4-triazole-5-thione chemical structure, C19H19N3OS, CAS 678558-71-9](/s/SQYRRWLGSBFELZ-UHFFFAOYSA-N.svg)
4-(4-Methoxyphenyl)-3-[2-(4-methylphenyl)cyclopropyl]-1H-1,2,4-triazole-5-thione
CAS 678558-71-9C19H19N3OS
![4-(4-Methylphenyl)-3-[2-(4-methylphenyl)cyclopropyl]-1H-1,2,4-triazole-5-thione chemical structure, C19H19N3S, CAS 676151-28-3](/s/BVCWUQWZSDUUFD-UHFFFAOYSA-N.svg)
4-(4-Methylphenyl)-3-[2-(4-methylphenyl)cyclopropyl]-1H-1,2,4-triazole-5-thione
CAS 676151-28-3C19H19N3S
![4-(3-Methoxyphenyl)-3-[2-(4-methylphenyl)cyclopropyl]-1H-1,2,4-triazole-5-thione chemical structure, C19H19N3OS, CAS 723253-39-2](/s/RZLCWCPSHYSWNR-UHFFFAOYSA-N.svg)
4-(3-Methoxyphenyl)-3-[2-(4-methylphenyl)cyclopropyl]-1H-1,2,4-triazole-5-thione
CAS 723253-39-2C19H19N3OS
![3-[2-(4-Chlorophenyl)cyclopropyl]-4-(4-methylphenyl)-1H-1,2,4-triazole-5-thione chemical structure, C18H16ClN3S, CAS 676643-25-7](/s/RHXMARFAJZENTK-UHFFFAOYSA-N.svg)
3-[2-(4-Chlorophenyl)cyclopropyl]-4-(4-methylphenyl)-1H-1,2,4-triazole-5-thione
CAS 676643-25-7C18H16ClN3S
![4-(4-Fluorophenyl)-3-[2-(4-methylphenyl)cyclopropyl]-1H-1,2,4-triazole-5-thione chemical structure, C18H16FN3S, CAS 676332-93-7](/s/VUDWBEWIOGNWKC-UHFFFAOYSA-N.svg)
4-(4-Fluorophenyl)-3-[2-(4-methylphenyl)cyclopropyl]-1H-1,2,4-triazole-5-thione
CAS 676332-93-7C18H16FN3S
![4-(4-Chlorophenyl)-3-[2-(4-chlorophenyl)cyclopropyl]-1H-1,2,4-triazole-5-thione chemical structure, C17H13Cl2N3S, CAS 675841-84-6](/s/LYPXCTPZMMXXAV-UHFFFAOYSA-N.svg)
4-(4-Chlorophenyl)-3-[2-(4-chlorophenyl)cyclopropyl]-1H-1,2,4-triazole-5-thione
CAS 675841-84-6C17H13Cl2N3S
![3-[2-(4-Chlorophenyl)cyclopropyl]-4-(4-methoxyphenyl)-1H-1,2,4-triazole-5-thione chemical structure, C18H16ClN3OS, CAS 677779-26-9](/s/QKLMFWKDGOWBSV-UHFFFAOYSA-N.svg)
3-[2-(4-Chlorophenyl)cyclopropyl]-4-(4-methoxyphenyl)-1H-1,2,4-triazole-5-thione
CAS 677779-26-9C18H16ClN3OS
![4-(2-Methylphenyl)-3-[(1R,2R)-2-phenylcyclopropyl]-1H-1,2,4-triazole-5-thione chemical structure, C18H17N3S, CAS 1212148-97-4](/s/BALZDSMVKZGXHP-LSDHHAIUSA-N.svg)
4-(2-Methylphenyl)-3-[(1R,2R)-2-phenylcyclopropyl]-1H-1,2,4-triazole-5-thione
CAS 1212148-97-4C18H17N3S
![4-(2-Chlorophenyl)-3-[(1R,2R)-2-phenylcyclopropyl]-1H-1,2,4-triazole-5-thione chemical structure, C17H14ClN3S, CAS 1212089-64-9](/s/MXSIORKOPSDDFW-QWHCGFSZSA-N.svg)
4-(2-Chlorophenyl)-3-[(1R,2R)-2-phenylcyclopropyl]-1H-1,2,4-triazole-5-thione
CAS 1212089-64-9C17H14ClN3S