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Murcko scaffold

Ring system with 4 rings and 16 atoms

8 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
16
Chemicals
8
With full pages
3
Scaffold SMILES

c1ccc(-n2ncc3c2C2CCC3C2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(-n2ncc3c2C2CCC3C2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 8 of 8 chemicals

1,10,10-Trimethyl-3-phenyl-3,4-diazatricyclo[5.2.1.0^{2,6}]deca-2(6),4-diene-5-carboxylic acid chemical structure, C18H20N2O2, CAS 326021-49-2
1,10,10-Trimethyl-3-phenyl-3,4-diazatricyclo[5.2.1.0^{2,6}]deca-2(6),4-diene-5-carboxylic acid
CAS 326021-49-2C18H20N2O2
{1,10,10-Trimethyl-3-phenyl-3,4-diazatricyclo[5.2.1.0^{2,6}]deca-2(6),4-dien-5-yl}methanol chemical structure, C18H22N2O, CAS 380353-29-7
{1,10,10-Trimethyl-3-phenyl-3,4-diazatricyclo[5.2.1.0^{2,6}]deca-2(6),4-dien-5-yl}methanol
CAS 380353-29-7C18H22N2O
(4R,7S)Tedalinab chemical structure, C19H21F2N3O, CAS 916591-02-1
(4R,7S)Tedalinab
CAS 916591-02-1C19H21F2N3O
Tedalinab chemical structure, C19H21F2N3O, CAS 916591-01-0
Tedalinab
CAS 916591-01-0C19H21F2N3O
1-(2,4-Difluorophenyl)-4,5,6,7-tetrahydro-1H-4,7-methanoindazole-3-carboxylic acid chemical structure, C15H12F2N2O2, CAS 916591-87-2
1-(2,4-Difluorophenyl)-4,5,6,7-tetrahydro-1H-4,7-methanoindazole-3-carboxylic acid
CAS 916591-87-2C15H12F2N2O2
Ethyl 1-(2,4-Difluorophenyl)-4,5,6,7-tetrahydro-4,7-methano-1H-indazole-3-carboxylate chemical structure, C17H16F2N2O2, CAS 916592-23-9
Ethyl 1-(2,4-Difluorophenyl)-4,5,6,7-tetrahydro-4,7-methano-1H-indazole-3-carboxylate
CAS 916592-23-9C17H16F2N2O2
(4S,7R)-1-(2,4-Difluorophenyl)-4,5,6,7-tetrahydro-1H-4,7-methanoindazole-3-carboxylic Acid chemical structure, C15H12F2N2O2, CAS 916591-88-3
(4S,7R)-1-(2,4-Difluorophenyl)-4,5,6,7-tetrahydro-1H-4,7-methanoindazole-3-carboxylic Acid
CAS 916591-88-3C15H12F2N2O2
Methyl 7,8,8-trimethyl-1-phenyl-4,5,6,7-tetrahydro-1H-4,7-methanoindazole-3-carboxylate chemical structure, C19H22N2O2, CAS 1706451-66-2
Methyl 7,8,8-trimethyl-1-phenyl-4,5,6,7-tetrahydro-1H-4,7-methanoindazole-3-carboxylate
CAS 1706451-66-2C19H22N2O2