Murcko scaffold
3,6-Dihydro-7H-1,2,3-triazolo(4,5-d)pyrimidin-7-one scaffold
52 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 10
- Chemicals
- 52
- With full pages
- 3
Scaffold SMILES
O=c1[nH]cnc2n[nH]nc12
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
![Murcko scaffold O=c1[nH]cnc2n[nH]nc12](/scaffold/OEEYCNOOAHGFHL-UHFFFAOYSA-N/structure.svg)
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 52 chemicals
![5-Amino-6-methyl-2H-triazolo[4,5-d]pyrimidin-7-one chemical structure, C5H6N6O, CAS 108800-71-1](/s/AQPLYUUYLFZMAG-UHFFFAOYSA-N.svg)
5-Amino-6-methyl-2H-triazolo[4,5-d]pyrimidin-7-one
CAS 108800-71-1C5H6N6O
![6-Methyl-2H-triazolo[4,5-d]pyrimidin-7-one chemical structure, C5H5N5O, CAS 61383-06-0](/s/CTWROIWRZJAKKE-UHFFFAOYSA-N.svg)
6-Methyl-2H-triazolo[4,5-d]pyrimidin-7-one
CAS 61383-06-0C5H5N5O
![4-Methyl-2H-triazolo[4,5-d]pyrimidin-7-one chemical structure, C5H5N5O, CAS 61383-07-1](/s/VJIOBPQOYGVVNL-UHFFFAOYSA-N.svg)
4-Methyl-2H-triazolo[4,5-d]pyrimidin-7-one
CAS 61383-07-1C5H5N5O
![N-Methyl-2-{3-methyl-7-oxo-3H,6H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-6-yl}acetamide chemical structure, C8H10N6O2, CAS 946276-56-8](/s/PSPOLRBREBLQSU-UHFFFAOYSA-N.svg)
N-Methyl-2-{3-methyl-7-oxo-3H,6H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-6-yl}acetamide
CAS 946276-56-8C8H10N6O2
![2-{3-Methyl-7-oxo-3H,6H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-6-yl}-N-(propan-2-yl)acetamide chemical structure, C10H14N6O2, CAS 946240-50-2](/s/MVAIVCBECCOTMZ-UHFFFAOYSA-N.svg)
2-{3-Methyl-7-oxo-3H,6H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-6-yl}-N-(propan-2-yl)acetamide
CAS 946240-50-2C10H14N6O2
![N-(tert-Butyl)-2-(3-methyl-7-oxo-3H-[1,2,3]triazolo[4,5-d]pyrimidin-6(7H)-yl)acetamide chemical structure, C11H16N6O2, CAS 946306-88-3](/s/WRYXZDQUTVRHHO-UHFFFAOYSA-N.svg)
N-(tert-Butyl)-2-(3-methyl-7-oxo-3H-[1,2,3]triazolo[4,5-d]pyrimidin-6(7H)-yl)acetamide
CAS 946306-88-3C11H16N6O2
![2-{3-Methyl-7-oxo-3H,6H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-6-yl}-N,N-bis(propan-2-yl)acetamide chemical structure, C13H20N6O2, CAS 946276-60-4](/s/FNJYFASXANKXBR-UHFFFAOYSA-N.svg)
2-{3-Methyl-7-oxo-3H,6H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-6-yl}-N,N-bis(propan-2-yl)acetamide
CAS 946276-60-4C13H20N6O2
![3-Methyl-6-propyl-3H,6H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one chemical structure, C8H11N5O, CAS 1058197-15-1](/s/VBGLKPIIHHAQDH-UHFFFAOYSA-N.svg)
3-Methyl-6-propyl-3H,6H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one
CAS 1058197-15-1C8H11N5O
![6-Butyl-3-methyl-3H,6H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one chemical structure, C9H13N5O, CAS 1070806-83-5](/s/OQCFURFKSOPMPA-UHFFFAOYSA-N.svg)
6-Butyl-3-methyl-3H,6H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one
CAS 1070806-83-5C9H13N5O
![3-Methyl-6-(prop-2-en-1-yl)-3H,6H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one chemical structure, C8H9N5O, CAS 1060181-04-5](/s/CXAQAXKWIGTMCF-UHFFFAOYSA-N.svg)
3-Methyl-6-(prop-2-en-1-yl)-3H,6H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one
CAS 1060181-04-5C8H9N5O
![3-Methyl-6-(2-methylpropyl)-3H,6H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one chemical structure, C9H13N5O, CAS 1070806-84-6](/s/PYGUUHHLCISYAD-UHFFFAOYSA-N.svg)
3-Methyl-6-(2-methylpropyl)-3H,6H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one
CAS 1070806-84-6C9H13N5O
![2-{3-Methyl-7-oxo-3H,6H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-6-yl}acetamide chemical structure, C7H8N6O2, CAS 1058432-52-2](/s/CELAPZMZQKEKMB-UHFFFAOYSA-N.svg)
2-{3-Methyl-7-oxo-3H,6H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-6-yl}acetamide
CAS 1058432-52-2C7H8N6O2
![2-{3-Methyl-7-oxo-3H,6H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-6-yl}-N-propylacetamide chemical structure, C10H14N6O2, CAS 1070806-92-6](/s/LCZRFPIDTSAZCA-UHFFFAOYSA-N.svg)
2-{3-Methyl-7-oxo-3H,6H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-6-yl}-N-propylacetamide
CAS 1070806-92-6C10H14N6O2
![N-Allyl-2-(3-methyl-7-oxo-3H-[1,2,3]triazolo[4,5-d]pyrimidin-6(7H)-yl)acetamide chemical structure, C10H12N6O2, CAS 1058432-65-7](/s/PWSZGZITGOYLIC-UHFFFAOYSA-N.svg)
N-Allyl-2-(3-methyl-7-oxo-3H-[1,2,3]triazolo[4,5-d]pyrimidin-6(7H)-yl)acetamide
CAS 1058432-65-7C10H12N6O2
![N-(2-Methoxyethyl)-2-{3-methyl-7-oxo-3H,6H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-6-yl}acetamide chemical structure, C10H14N6O3, CAS 1058197-25-3](/s/OSMNDNVZCJDVDT-UHFFFAOYSA-N.svg)
N-(2-Methoxyethyl)-2-{3-methyl-7-oxo-3H,6H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-6-yl}acetamide
CAS 1058197-25-3C10H14N6O3
![N-Ethyl-2-{3-methyl-7-oxo-3H,6H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-6-yl}acetamide chemical structure, C9H12N6O2, CAS 1058432-66-8](/s/YCWVSNVCQBRKSO-UHFFFAOYSA-N.svg)
N-Ethyl-2-{3-methyl-7-oxo-3H,6H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-6-yl}acetamide
CAS 1058432-66-8C9H12N6O2
![Ethyl 2-{3-methyl-7-oxo-3H,6H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-6-yl}acetate chemical structure, C9H11N5O3, CAS 1058197-31-1](/s/SVHVYKQUOCJVBY-UHFFFAOYSA-N.svg)
Ethyl 2-{3-methyl-7-oxo-3H,6H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-6-yl}acetate
CAS 1058197-31-1C9H11N5O3
![3-Ethyl-6-methyl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7(6H)-one chemical structure, C7H9N5O, CAS 1070807-00-9](/s/DGOJDUGFLBJTHS-UHFFFAOYSA-N.svg)
3-Ethyl-6-methyl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7(6H)-one
CAS 1070807-00-9C7H9N5O
![3,6-Diethyl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7(6H)-one chemical structure, C8H11N5O, CAS 1058432-79-3](/s/HXHXRWVCSJOEQS-UHFFFAOYSA-N.svg)
3,6-Diethyl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7(6H)-one
CAS 1058432-79-3C8H11N5O
![3-Ethyl-6-propyl-3H,6H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one chemical structure, C9H13N5O, CAS 1060182-39-9](/s/SVXUZAPKNSMNMA-UHFFFAOYSA-N.svg)
3-Ethyl-6-propyl-3H,6H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one
CAS 1060182-39-9C9H13N5O
![6-Butyl-3-ethyl-3H,6H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one chemical structure, C10H15N5O, CAS 1070807-01-0](/s/KQJKFVTVVLVOMI-UHFFFAOYSA-N.svg)
6-Butyl-3-ethyl-3H,6H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one
CAS 1070807-01-0C10H15N5O
![3-Ethyl-6-(prop-2-en-1-yl)-3H,6H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one chemical structure, C9H11N5O, CAS 1058197-34-4](/s/DCPVVDCCBVQROD-UHFFFAOYSA-N.svg)
3-Ethyl-6-(prop-2-en-1-yl)-3H,6H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one
CAS 1058197-34-4C9H11N5O
![Ethyl 2-(2-{3-ethyl-7-oxo-3H,6H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-6-yl}acetamido)acetate chemical structure, C12H16N6O4, CAS 1058197-49-1](/s/FEIUROUYNUAZTC-UHFFFAOYSA-N.svg)
Ethyl 2-(2-{3-ethyl-7-oxo-3H,6H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-6-yl}acetamido)acetate
CAS 1058197-49-1C12H16N6O4
![2-{3-Ethyl-7-oxo-3H,6H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-6-yl}-N-methylacetamide chemical structure, C9H12N6O2, CAS 1070807-20-3](/s/LWVUKLAWHADOEN-UHFFFAOYSA-N.svg)
2-{3-Ethyl-7-oxo-3H,6H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-6-yl}-N-methylacetamide
CAS 1070807-20-3C9H12N6O2
- 2-{3-Ethyl-7-oxo-3H,6H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-6-yl}-N-propylacetamide1058433-15-0C11H16N6O2
- 2-{3-Ethyl-7-oxo-3H,6H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-6-yl}-N-(prop-2-en-1-yl)acetamide1060183-98-3C11H14N6O2
- 2-{3-Ethyl-7-oxo-3H,6H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-6-yl}-N-(propan-2-yl)acetamide1058197-53-7C11H16N6O2
- N-tert-Butyl-2-{3-ethyl-7-oxo-3H,6H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-6-yl}acetamide1070807-21-4C12H18N6O2
- 2-{3-Ethyl-7-oxo-3H,6H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-6-yl}-N,N-bis(propan-2-yl)acetamide1058433-19-4C14H22N6O2
- 2-{3-Ethyl-7-oxo-3H,6H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-6-yl}-N-(2-methoxyethyl)acetamide1060184-06-6C11H16N6O3
- N-Ethyl-2-{3-ethyl-7-oxo-3H,6H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-6-yl}acetamide1070807-23-6C10H14N6O2
- Methyl 2-(3-ethyl-7-oxo-3H-[1,2,3]triazolo[4,5-d]pyrimidin-6(7H)-yl)acetate1070807-30-5C9H11N5O3
- Ethyl 2-{3-ethyl-7-oxo-3H,6H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-6-yl}acetate1060184-70-4C10H13N5O3
- Ethyl 2-(2-(3-methyl-7-oxo-3H-[1,2,3]triazolo[4,5-d]pyrimidin-6(7H)-yl)acetamido)acetate1021111-67-0C11H14N6O4
- 6-(sec-Butyl)-3-methyl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7(6H)-one1058432-47-5C9H13N5O
- 2-(7-Oxo-3H-[1,2,3]triazolo[4,5-d]pyrimidin-6(7H)-yl)acetic acid1698844-56-2C6H5N5O3
- 60 suppliers8-Azaguanine134-58-7C4H4N6O
- 6 suppliers3,6-Dihydro-7H-1,2,3-triazolo(4,5-d)pyrimidin-7-one2683-90-1C4H3N5O
- 5-Amino-3-butyl-2,3-dihydro-7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one6324-90-9C8H12N6O
- 5-Amino-3-ethyl-2,3-dihydro-7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one5457-90-9C6H8N6O
- 2-Amino-6-(7-oxo-6H-triazolo[4,5-d]pyrimidin-3-yl)hexanoic acid55739-68-9C10H14N6O3
- 6-(7-Oxo-6H-triazolo[4,5-d]pyrimidin-3-yl)hexanoic acid55739-66-7C10H13N5O3
- 3-Methyl-5-(methylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7(6H)-one65023-35-0C6H7N5OS
- 5-(Methylthio)-3,6-dihydro-7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one62700-63-4C5H5N5OS
- 3-Methyl-3H,6H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one20420-86-4C5H5N5O
- 3-Ethyl-3,6-dihydro-7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one1105195-78-5C6H7N5O
- 5-Amino-3-methyl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-ol425427-94-7C5H6N6O
- 1,6-Dihydro-1-methyl-7H-1,2,3-triazolo[4,5-d]pyrimidin-7-one36185-38-3C5H5N5O
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