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Murcko scaffold

N-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-2-(1,3-dioxoisoindolin-2-yl)acetamide scaffold

3 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
25
Chemicals
3
With full pages
2
Scaffold SMILES

O=C(CN1C(=O)c2ccccc2C1=O)Nc1ccc2c(c1)OCCO2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the N-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-2-(1,3-dioxoisoindolin-2-yl)acetamide page
Murcko scaffold O=C(CN1C(=O)c2ccccc2C1=O)Nc1ccc2c(c1)OCCO2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 3 of 3 chemicals

2-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-4-methyl-pentanoic acid (2,3-dihydro-benzo[1,4]dioxin-6-yl)-amide chemical structure, C22H22N2O5, CAS 333431-50-8
2-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-4-methyl-pentanoic acid (2,3-dihydro-benzo[1,4]dioxin-6-yl)-amide
CAS 333431-50-8C22H22N2O5
N-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-2-(1,3-dioxoisoindolin-2-yl)acetamide chemical structure, C18H14N2O5, CAS 329907-19-9
N-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-2-(1,3-dioxoisoindolin-2-yl)acetamide
CAS 329907-19-9C18H14N2O5
N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-3-methylbutanamide chemical structure, C21H20N2O5, CAS 301307-12-0
N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-3-methylbutanamide
CAS 301307-12-0C21H20N2O5