Murcko scaffold
Ring system with 5 rings and 29 atoms
30 chemicals on CompoundList share this ring system.
- Rings
- 5
- Scaffold atoms
- 29
- Chemicals
- 30
- With full pages
- 3
Scaffold SMILES
c1ccc(CNc2ncnc3c2c(-c2ccccc2)cn3-c2ccccc2)cc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 30 of 30 chemicals
![N-Benzyl-7-(4-methoxyphenyl)-5-phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine chemical structure, C26H22N4O, CAS 477227-84-2](/s/UQQHFGYIEMXSCM-UHFFFAOYSA-N.svg)
N-Benzyl-7-(4-methoxyphenyl)-5-phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine
CAS 477227-84-2C26H22N4O
![N-(4-Fluorobenzyl)-7-(4-methoxyphenyl)-5-phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine chemical structure, C26H21FN4O, CAS 477227-91-1](/s/UGPUEDWXURAFJK-UHFFFAOYSA-N.svg)
N-(4-Fluorobenzyl)-7-(4-methoxyphenyl)-5-phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine
CAS 477227-91-1C26H21FN4O
![N-(4-Fluorobenzyl)-5,7-diphenyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine chemical structure, C25H19FN4, CAS 477226-19-0](/s/SJZWYXIJZGHJPB-UHFFFAOYSA-N.svg)
N-(4-Fluorobenzyl)-5,7-diphenyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine
CAS 477226-19-0C25H19FN4
![N-(2-Chlorobenzyl)-7-(4-chlorophenyl)-5-phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine chemical structure, C25H18Cl2N4, CAS 477226-97-4](/s/JODSMGWEZDCISC-UHFFFAOYSA-N.svg)
N-(2-Chlorobenzyl)-7-(4-chlorophenyl)-5-phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine
CAS 477226-97-4C25H18Cl2N4
![N-(2-Chlorobenzyl)-5,7-diphenyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine chemical structure, C25H19ClN4, CAS 477226-13-4](/s/OSBBUTDEUYAJCF-UHFFFAOYSA-N.svg)
N-(2-Chlorobenzyl)-5,7-diphenyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine
CAS 477226-13-4C25H19ClN4
![N-[(4-Fluorophenyl)methyl]-7-(4-methylphenyl)-5-phenylpyrrolo[2,3-d]pyrimidin-4-amine chemical structure, C26H21FN4, CAS 477233-05-9](/s/PPBHVUOYTJWSNH-UHFFFAOYSA-N.svg)
N-[(4-Fluorophenyl)methyl]-7-(4-methylphenyl)-5-phenylpyrrolo[2,3-d]pyrimidin-4-amine
CAS 477233-05-9C26H21FN4
![N-[(2-Chlorophenyl)methyl]-5-phenyl-7-[3-(trifluoromethyl)phenyl]pyrrolo[2,3-d]pyrimidin-4-amine chemical structure, C26H18ClF3N4, CAS 477236-54-7](/s/UTLNDMMVFHEHIJ-UHFFFAOYSA-N.svg)
N-[(2-Chlorophenyl)methyl]-5-phenyl-7-[3-(trifluoromethyl)phenyl]pyrrolo[2,3-d]pyrimidin-4-amine
CAS 477236-54-7C26H18ClF3N4
![N-(4-Methylbenzyl)-5-phenyl-7-[3-(trifluoromethyl)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine chemical structure, C27H21F3N4, CAS 477236-65-0](/s/QERMDYLQNWKAQE-UHFFFAOYSA-N.svg)
N-(4-Methylbenzyl)-5-phenyl-7-[3-(trifluoromethyl)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine
CAS 477236-65-0C27H21F3N4
![N-[(4-Fluorophenyl)methyl]-5-phenyl-7-[3-(trifluoromethyl)phenyl]pyrrolo[2,3-d]pyrimidin-4-amine chemical structure, C26H18F4N4, CAS 477236-68-3](/s/PXVNVPACBNGHOT-UHFFFAOYSA-N.svg)
N-[(4-Fluorophenyl)methyl]-5-phenyl-7-[3-(trifluoromethyl)phenyl]pyrrolo[2,3-d]pyrimidin-4-amine
CAS 477236-68-3C26H18F4N4
![N-(4-Methoxybenzyl)-5,7-diphenyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine chemical structure, C26H22N4O, CAS 477226-16-7](/s/MVIZGONOJMXBFO-UHFFFAOYSA-N.svg)
N-(4-Methoxybenzyl)-5,7-diphenyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine
CAS 477226-16-7C26H22N4O
![N-Benzyl-7-(4-fluorophenyl)-5-phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine chemical structure, C25H19FN4, CAS 477230-01-6](/s/OFZZKPVPEOVWLS-UHFFFAOYSA-N.svg)
N-Benzyl-7-(4-fluorophenyl)-5-phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine
CAS 477230-01-6C25H19FN4
![7-(4-Methoxyphenyl)-5-phenyl-N-(1-phenylethyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine chemical structure, C27H24N4O, CAS 477228-33-4](/s/BPWLWNHYOBSARB-UHFFFAOYSA-N.svg)
7-(4-Methoxyphenyl)-5-phenyl-N-(1-phenylethyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine
CAS 477228-33-4C27H24N4O
![N-[(3-Chlorophenyl)methyl]-7-(4-methylphenyl)-5-phenylpyrrolo[2,3-d]pyrimidin-4-amine chemical structure, C26H21ClN4, CAS 477233-01-5](/s/URVDCEYIUUXMOK-UHFFFAOYSA-N.svg)
N-[(3-Chlorophenyl)methyl]-7-(4-methylphenyl)-5-phenylpyrrolo[2,3-d]pyrimidin-4-amine
CAS 477233-01-5C26H21ClN4
![7-(3-Chloro-4-methylphenyl)-N-(4-fluorobenzyl)-5-phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine chemical structure, C26H20ClFN4, CAS 477229-65-5](/s/CIHIMQVFNYIURQ-UHFFFAOYSA-N.svg)
7-(3-Chloro-4-methylphenyl)-N-(4-fluorobenzyl)-5-phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine
CAS 477229-65-5C26H20ClFN4
![N-[(2-Chlorophenyl)methyl]-7-(4-methoxyphenyl)-5-phenylpyrrolo[2,3-d]pyrimidin-4-amine chemical structure, C26H21ClN4O, CAS 477227-86-4](/s/TYLMGURRYFCKRV-UHFFFAOYSA-N.svg)
N-[(2-Chlorophenyl)methyl]-7-(4-methoxyphenyl)-5-phenylpyrrolo[2,3-d]pyrimidin-4-amine
CAS 477227-86-4C26H21ClN4O
![N-[(3-Chlorophenyl)methyl]-7-(4-methoxyphenyl)-5-phenylpyrrolo[2,3-d]pyrimidin-4-amine chemical structure, C26H21ClN4O, CAS 477227-87-5](/s/WUCWCMWYPHQAAD-UHFFFAOYSA-N.svg)
N-[(3-Chlorophenyl)methyl]-7-(4-methoxyphenyl)-5-phenylpyrrolo[2,3-d]pyrimidin-4-amine
CAS 477227-87-5C26H21ClN4O
![N-(4-Methylbenzyl)-7-(3-methylphenyl)-5-phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine chemical structure, C27H24N4, CAS 477228-75-4](/s/WRKPKJQSDGXOFI-UHFFFAOYSA-N.svg)
N-(4-Methylbenzyl)-7-(3-methylphenyl)-5-phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine
CAS 477228-75-4C27H24N4
![N-(2-Chlorobenzyl)-7-(4-ethoxyphenyl)-5-phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine chemical structure, C27H23ClN4O, CAS 477234-38-1](/s/MKKKUZNTFVASSH-UHFFFAOYSA-N.svg)
N-(2-Chlorobenzyl)-7-(4-ethoxyphenyl)-5-phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine
CAS 477234-38-1C27H23ClN4O
![7-(4-Ethoxyphenyl)-N-(4-fluorobenzyl)-5-phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine chemical structure, C27H23FN4O, CAS 477234-46-1](/s/LZJQLOOESYFBKB-UHFFFAOYSA-N.svg)
7-(4-Ethoxyphenyl)-N-(4-fluorobenzyl)-5-phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine
CAS 477234-46-1C27H23FN4O
![7-(3-Chlorophenyl)-N-(4-methylbenzyl)-5-phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine chemical structure, C26H21ClN4, CAS 477231-41-7](/s/BMBFJEFCIHKNMT-UHFFFAOYSA-N.svg)
7-(3-Chlorophenyl)-N-(4-methylbenzyl)-5-phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine
CAS 477231-41-7C26H21ClN4
![N-(4-Methoxybenzyl)-5-phenyl-7-(p-tolyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine chemical structure, C27H24N4O, CAS 477233-03-7](/s/UQWKAKBDHQVTHH-UHFFFAOYSA-N.svg)
N-(4-Methoxybenzyl)-5-phenyl-7-(p-tolyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine
CAS 477233-03-7C27H24N4O
![7-(4-Bromophenyl)-N-(2-methoxybenzyl)-5-phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine chemical structure, C26H21BrN4O, CAS 477231-75-7](/s/SVHZEPLGIKJTIU-UHFFFAOYSA-N.svg)
7-(4-Bromophenyl)-N-(2-methoxybenzyl)-5-phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine
CAS 477231-75-7C26H21BrN4O
![N-Benzyl-5-phenyl-7-[3-(trifluoromethyl)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine chemical structure, C26H19F3N4, CAS 477236-48-9](/s/LIDMXWDPIOZFKD-UHFFFAOYSA-N.svg)
N-Benzyl-5-phenyl-7-[3-(trifluoromethyl)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine
CAS 477236-48-9C26H19F3N4
![N-[(2-Methoxyphenyl)methyl]-7-(4-methylphenyl)-5-phenylpyrrolo[2,3-d]pyrimidin-4-amine chemical structure, C27H24N4O, CAS 477233-02-6](/s/QDNXWIYKQPNYAB-UHFFFAOYSA-N.svg)
N-[(2-Methoxyphenyl)methyl]-7-(4-methylphenyl)-5-phenylpyrrolo[2,3-d]pyrimidin-4-amine
CAS 477233-02-6C27H24N4O
- 7-(3-Chloro-4-methylphenyl)-N-(3-chlorobenzyl)-5-phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine477229-58-6C26H20Cl2N4
- N-(3-Chlorobenzyl)-7-(3-methylphenyl)-5-phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine477228-72-1C26H21ClN4
- N-Benzyl-7-(4-bromophenyl)-5-phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine477231-67-7C25H19BrN4
- 7-(3-Chloro-4-methylphenyl)-N-(2-chlorobenzyl)-5-phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine477229-57-5C26H20Cl2N4
- 7-(3-Chloro-4-methylphenyl)-N-(4-methoxybenzyl)-5-phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine477229-61-1C27H23ClN4O
- N-(2-Chlorobenzyl)-5-phenyl-7-(p-tolyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine477233-00-4C26H21ClN4