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Murcko scaffold

Ring system with 3 rings and 20 atoms

6 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
20
Chemicals
6
With full pages
3
Scaffold SMILES

O=C(CSc1nnc(-c2ccco2)[nH]1)Nc1nncs1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CSc1nnc(-c2ccco2)[nH]1)Nc1nncs1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 6 of 6 chemicals

2-(4-Ethyl-5-furan-2-yl-4H-[1,2,4]triazol-3-ylsulfanyl)-N-(5-methyl-[1,3,4]thiadiazol-2-yl)-acetamide chemical structure, C13H14N6O2S2, CAS 557068-25-4
2-(4-Ethyl-5-furan-2-yl-4H-[1,2,4]triazol-3-ylsulfanyl)-N-(5-methyl-[1,3,4]thiadiazol-2-yl)-acetamide
CAS 557068-25-4C13H14N6O2S2
2-{[4-Allyl-5-(2-furyl)-4H-1,2,4-triazol-3-yl]thio}-N-(5-ethyl-1,3,4-thiadiazol-2-yl)acetamide chemical structure, C15H16N6O2S2, CAS 442642-30-0
2-{[4-Allyl-5-(2-furyl)-4H-1,2,4-triazol-3-yl]thio}-N-(5-ethyl-1,3,4-thiadiazol-2-yl)acetamide
CAS 442642-30-0C15H16N6O2S2
2-[[5-(Furan-2-yl)-4-prop-2-enyl-1,2,4-triazol-3-yl]sulfanyl]-N-(5-methyl-1,3,4-thiadiazol-2-yl)acetamide chemical structure, C14H14N6O2S2, CAS 681838-37-9
2-[[5-(Furan-2-yl)-4-prop-2-enyl-1,2,4-triazol-3-yl]sulfanyl]-N-(5-methyl-1,3,4-thiadiazol-2-yl)acetamide
CAS 681838-37-9C14H14N6O2S2
2-[[5-(Furan-2-yl)-4-methyl-1,2,4-triazol-3-yl]sulfanyl]-N-(1,3,4-thiadiazol-2-yl)acetamide chemical structure, C11H10N6O2S2, CAS 878442-44-5
2-[[5-(Furan-2-yl)-4-methyl-1,2,4-triazol-3-yl]sulfanyl]-N-(1,3,4-thiadiazol-2-yl)acetamide
CAS 878442-44-5C11H10N6O2S2
2-[[5-(Furan-2-yl)-4-propan-2-yl-1,2,4-triazol-3-yl]sulfanyl]-N-(1,3,4-thiadiazol-2-yl)acetamide chemical structure, C13H14N6O2S2, CAS 888309-17-9
2-[[5-(Furan-2-yl)-4-propan-2-yl-1,2,4-triazol-3-yl]sulfanyl]-N-(1,3,4-thiadiazol-2-yl)acetamide
CAS 888309-17-9C13H14N6O2S2
N-(5-Ethyl-1,3,4-thiadiazol-2-yl)-2-{[5-(furan-2-yl)-4-(propan-2-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide chemical structure, C15H18N6O2S2, CAS 879058-39-6
N-(5-Ethyl-1,3,4-thiadiazol-2-yl)-2-{[5-(furan-2-yl)-4-(propan-2-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide
CAS 879058-39-6C15H18N6O2S2