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Murcko scaffold

Spiro[indene-2,4'-piperidin]-1(3H)-one scaffold

39 chemicals on CompoundList share this ring system.

Rings: 3
Scaffold atoms: 15
Chemicals: 39
With full pages: 4

Scaffold SMILES

O=C1c2ccccc2CC12CCNCC2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold Open the Spiro[indene-2,4'-piperidin]-1(3H)-one page

Murcko scaffold O=C1c2ccccc2CC12CCNCC2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 39 of 39 chemicals

1'-Acetyl-6-nitrospiro[indene-2,4'-piperidin]-1(3H)-one chemical structure, C15H16N2O4, CAS 136080-26-7

1'-Acetyl-6-nitrospiro[indene-2,4'-piperidin]-1(3H)-one

CAS 136080-26-7C₁₅H₁₆N₂O₄

Spiro[indene-2,4'-piperidin]-1(3H)-one chemical structure, C13H15NO, CAS 136080-25-6

Spiro[indene-2,4'-piperidin]-1(3H)-one

CAS 136080-25-6C₁₃H₁₅NO

6-Methoxyspiro[indene-2,4'-piperidin]-1(3H)-one chemical structure, C14H17NO2, CAS 209280-25-1

6-Methoxyspiro[indene-2,4'-piperidin]-1(3H)-one

CAS 209280-25-1C₁₄H₁₇NO₂

tert-Butyl 1-oxo-1,3-dihydrospiro[indene-2,4'-piperidine]-1'-carboxylate chemical structure, C18H23NO3, CAS 1228079-29-5

tert-Butyl 1-oxo-1,3-dihydrospiro[indene-2,4'-piperidine]-1'-carboxylate

CAS 1228079-29-5C₁₈H₂₃NO₃

Spiro[indene-2,4'-piperidin]-1(3H)-one hydrochloride chemical structure, C13H16ClNO, CAS 185525-49-9

Spiro[indene-2,4'-piperidin]-1(3H)-one hydrochloride

CAS 185525-49-9C₁₃H₁₆ClNO

5-Methoxy-1,3-dihydrospiro[indene-2,4'-piperidin]-3-one hydrochloride chemical structure, C14H18ClNO2, CAS 253783-77-6

5-Methoxy-1,3-dihydrospiro[indene-2,4'-piperidin]-3-one hydrochloride

CAS 253783-77-6C₁₄H₁₈ClNO₂

5-Methoxyspiro[indene-2,4'-piperidin]-1(3H)-one chemical structure, C14H17NO2, CAS 1417917-87-3

5-Methoxyspiro[indene-2,4'-piperidin]-1(3H)-one

CAS 1417917-87-3C₁₄H₁₇NO₂

5-Fluorospiro[indene-2,4'-piperidin]-1(3H)-one chemical structure, C13H14FNO, CAS 1417917-61-3

5-Fluorospiro[indene-2,4'-piperidin]-1(3H)-one

CAS 1417917-61-3C₁₃H₁₄FNO

Ethyl 5-fluoro-1-oxo-1,3-dihydrospiro[indene-2,4'-piperidine]-1'-carboxylate chemical structure, C16H18FNO3, CAS 1417917-60-2

Ethyl 5-fluoro-1-oxo-1,3-dihydrospiro[indene-2,4'-piperidine]-1'-carboxylate

CAS 1417917-60-2C₁₆H₁₈FNO₃

5-Fluorospiro[indene-2,4'-piperidin]-1(3H)-one hydrochloride chemical structure, C13H15ClFNO, CAS 1447608-08-3

5-Fluorospiro[indene-2,4'-piperidin]-1(3H)-one hydrochloride

CAS 1447608-08-3C₁₃H₁₅ClFNO

5-Methoxyspiro(indene-2,4'-piperidin)-1(3H)-one hydrochloride chemical structure, C14H18ClNO2, CAS 1447606-13-4

5-Methoxyspiro(indene-2,4'-piperidin)-1(3H)-one hydrochloride

CAS 1447606-13-4C₁₄H₁₈ClNO₂

tert-Butyl 4-fluoro-1-oxo-1,3-dihydrospiro[indene-2,4'-piperidine]-1'-carboxylate chemical structure, C18H22FNO3, CAS 2377354-94-2

tert-Butyl 4-fluoro-1-oxo-1,3-dihydrospiro[indene-2,4'-piperidine]-1'-carboxylate

CAS 2377354-94-2C₁₈H₂₂FNO₃

tert-Butyl 6-bromo-1-oxo-1,3-dihydrospiro[indene-2,4'-piperidine]-1'-carboxylate chemical structure, C18H22BrNO3, CAS 2245084-41-5

tert-Butyl 6-bromo-1-oxo-1,3-dihydrospiro[indene-2,4'-piperidine]-1'-carboxylate

CAS 2245084-41-5C₁₈H₂₂BrNO₃

tert-Butyl 6-chloro-1-oxo-1,3-dihydrospiro[indene-2,4'-piperidine]-1'-carboxylate chemical structure, C18H22ClNO3, CAS 2245084-42-6

tert-Butyl 6-chloro-1-oxo-1,3-dihydrospiro[indene-2,4'-piperidine]-1'-carboxylate

CAS 2245084-42-6C₁₈H₂₂ClNO₃

tert-Butyl 7-methoxy-1-oxo-1,3-dihydrospiro[indene-2,4'-piperidine]-1'-carboxylate chemical structure, C19H25NO4, CAS 2245084-35-7

tert-Butyl 7-methoxy-1-oxo-1,3-dihydrospiro[indene-2,4'-piperidine]-1'-carboxylate

CAS 2245084-35-7C₁₉H₂₅NO₄

tert-Butyl 5-bromo-1-oxo-1,3-dihydrospiro[indene-2,4'-piperidine]-1'-carboxylate chemical structure, C18H22BrNO3, CAS 2245084-49-3

tert-Butyl 5-bromo-1-oxo-1,3-dihydrospiro[indene-2,4'-piperidine]-1'-carboxylate

CAS 2245084-49-3C₁₈H₂₂BrNO₃

tert-Butyl 6-amino-1-oxo-1,3-dihydrospiro[indene-2,4'-piperidine]-1'-carboxylate chemical structure, C18H24N2O3, CAS 2245084-64-2

tert-Butyl 6-amino-1-oxo-1,3-dihydrospiro[indene-2,4'-piperidine]-1'-carboxylate

CAS 2245084-64-2C₁₈H₂₄N₂O₃

tert-Butyl 5-methyl-3-oxospiro[1H-indene-2,4'-piperidine]-1'-carboxylate chemical structure, C19H25NO3, CAS 2245084-36-8

tert-Butyl 5-methyl-3-oxospiro[1H-indene-2,4'-piperidine]-1'-carboxylate

CAS 2245084-36-8C₁₉H₂₅NO₃

tert-Butyl 5-methoxy-1-oxo-1,3-dihydrospiro[indene-2,4'-piperidine]-1'-carboxylate chemical structure, C19H25NO4, CAS 2245084-37-9

tert-Butyl 5-methoxy-1-oxo-1,3-dihydrospiro[indene-2,4'-piperidine]-1'-carboxylate

CAS 2245084-37-9C₁₉H₂₅NO₄

tert-Butyl 4-methoxy-1-oxo-1,3-dihydrospiro[indene-2,4'-piperidine]-1'-carboxylate chemical structure, C19H25NO4, CAS 2245084-38-0

tert-Butyl 4-methoxy-1-oxo-1,3-dihydrospiro[indene-2,4'-piperidine]-1'-carboxylate

CAS 2245084-38-0C₁₉H₂₅NO₄

1'-Boc-spiro[6-methoxy-indene-2,4'-piperidin]-1(3H)-one chemical structure, C19H25NO4, CAS 2245084-34-6

1'-Boc-spiro[6-methoxy-indene-2,4'-piperidin]-1(3H)-one

CAS 2245084-34-6C₁₉H₂₅NO₄

tert-Butyl 5,6,7-trifluoro-1-oxo-1,3-dihydrospiro[indene-2,4'-piperidine]-1'-carboxylate chemical structure, C18H20F3NO3, CAS 2245084-47-1

tert-Butyl 5,6,7-trifluoro-1-oxo-1,3-dihydrospiro[indene-2,4'-piperidine]-1'-carboxylate

CAS 2245084-47-1C₁₈H₂₀F₃NO₃

5-Chlorospiro[indene-2,4'-piperidin]-1(3H)-one hydrochloride chemical structure, C13H15Cl2NO, CAS 2415987-39-0

5-Chlorospiro[indene-2,4'-piperidin]-1(3H)-one hydrochloride

CAS 2415987-39-0C₁₃H₁₅Cl₂NO

5-Chlorospiro[indene-2,4'-piperidin]-1(3H)-one chemical structure, C13H14ClNO, CAS 2415987-38-9

5-Chlorospiro[indene-2,4'-piperidin]-1(3H)-one

CAS 2415987-38-9C₁₃H₁₄ClNO