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Murcko scaffold

4-(1,2,4-Oxadiazol-3-yl)piperidine scaffold

39 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
11
Chemicals
39
With full pages
4
Scaffold SMILES

c1nc(C2CCNCC2)no1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 4-(1,2,4-Oxadiazol-3-yl)piperidine page
Murcko scaffold c1nc(C2CCNCC2)no1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 39 of 39 chemicals

4-(5-Methyl-1,2,4-oxadiazol-3-yl)piperidine hydrochloride chemical structure, C8H14ClN3O, CAS 280110-73-8
4-(5-Methyl-1,2,4-oxadiazol-3-yl)piperidine hydrochloride
CAS 280110-73-8C8H14ClN3O
5-Methyl-3-(piperidin-4-yl)-1,2,4-oxadiazole chemical structure, C8H13N3O, CAS 757175-70-5
5-Methyl-3-(piperidin-4-yl)-1,2,4-oxadiazole
CAS 757175-70-5C8H13N3O
N-(4-(5-Methyl-1,2,4-oxadiazol-3-yl)piperidin-4-yl)acetamide chemical structure, C10H16N4O2, CAS 1153571-30-2
N-(4-(5-Methyl-1,2,4-oxadiazol-3-yl)piperidin-4-yl)acetamide
CAS 1153571-30-2C10H16N4O2
N-[4-(5-Methyl-1,2,4-oxadiazol-3-yl)piperidin-4-yl]acetamide hydrochloride chemical structure, C10H17ClN4O2, CAS 1153559-30-8
N-[4-(5-Methyl-1,2,4-oxadiazol-3-yl)piperidin-4-yl]acetamide hydrochloride
CAS 1153559-30-8C10H17ClN4O2
tert-Butyl 4-(5-methyl-1,2,4-oxadiazol-3-yl)piperidine-1-carboxylate chemical structure, C13H21N3O3, CAS 280110-66-9
tert-Butyl 4-(5-methyl-1,2,4-oxadiazol-3-yl)piperidine-1-carboxylate
CAS 280110-66-9C13H21N3O3
4-[5-(Propan-2-yl)-1,2,4-oxadiazol-3-yl]piperidine chemical structure, C10H17N3O, CAS 913321-45-6
4-[5-(Propan-2-yl)-1,2,4-oxadiazol-3-yl]piperidine
CAS 913321-45-6C10H17N3O
4-(1,2,4-Oxadiazol-3-yl)piperidine chemical structure, C7H11N3O, CAS 1250117-85-1
4-(1,2,4-Oxadiazol-3-yl)piperidine
CAS 1250117-85-1C7H11N3O
Piperidine, 4-(5-propyl-1,2,4-oxadiazol-3-yl)- chemical structure, C10H17N3O, CAS 1351562-60-1
Piperidine, 4-(5-propyl-1,2,4-oxadiazol-3-yl)-
CAS 1351562-60-1C10H17N3O
4-[5-(Trifluoromethyl)-1,2,4-oxadiazol-3-yl]piperidine chemical structure, C8H10F3N3O, CAS 1272226-67-1
4-[5-(Trifluoromethyl)-1,2,4-oxadiazol-3-yl]piperidine
CAS 1272226-67-1C8H10F3N3O
4-(5-Hydroxymethyl-[1,2,4]oxadiazol-3-yl)-piperidine-1-carboxylic acid tert-butyl ester chemical structure, C13H21N3O4, CAS 1044136-50-6
4-(5-Hydroxymethyl-[1,2,4]oxadiazol-3-yl)-piperidine-1-carboxylic acid tert-butyl ester
CAS 1044136-50-6C13H21N3O4
4-[5-(2,2-Dimethylpropyl)-1,2,4-oxadiazol-3-yl]piperidine chemical structure, C12H21N3O, CAS 874571-77-4
4-[5-(2,2-Dimethylpropyl)-1,2,4-oxadiazol-3-yl]piperidine
CAS 874571-77-4C12H21N3O
tert-Butyl 4-(5-isopropyl-1,2,4-oxadiazol-3-yl)piperidine-1-carboxylate chemical structure, C15H25N3O3, CAS 913264-43-4
tert-Butyl 4-(5-isopropyl-1,2,4-oxadiazol-3-yl)piperidine-1-carboxylate
CAS 913264-43-4C15H25N3O3
5-Ethyl-3-(piperidin-4-yl)-1,2,4-oxadiazole chemical structure, C9H15N3O, CAS 1226148-67-9
5-Ethyl-3-(piperidin-4-yl)-1,2,4-oxadiazole
CAS 1226148-67-9C9H15N3O
tert-Butyl 4-[5-(chloromethyl)-1,2,4-oxadiazol-3-yl]piperidine-1-carboxylate chemical structure, C13H20ClN3O3, CAS 1394838-35-7
tert-Butyl 4-[5-(chloromethyl)-1,2,4-oxadiazol-3-yl]piperidine-1-carboxylate
CAS 1394838-35-7C13H20ClN3O3
4-[5-(Difluoromethyl)-1,2,4-oxadiazol-3-yl]piperidine chemical structure, C8H11F2N3O, CAS 1342993-60-5
4-[5-(Difluoromethyl)-1,2,4-oxadiazol-3-yl]piperidine
CAS 1342993-60-5C8H11F2N3O
5-Isopropyl-3-(piperidin-4-yl)-1,2,4-oxadiazole hydrochloride chemical structure, C10H18ClN3O, CAS 913264-44-5
5-Isopropyl-3-(piperidin-4-yl)-1,2,4-oxadiazole hydrochloride
CAS 913264-44-5C10H18ClN3O
4-[5-(1,1-Difluoroethyl)-1,2,4-oxadiazol-3-yl]piperidine chemical structure, C9H13F2N3O, CAS 1351562-63-4
4-[5-(1,1-Difluoroethyl)-1,2,4-oxadiazol-3-yl]piperidine
CAS 1351562-63-4C9H13F2N3O
4-(5-(Trifluoromethyl)-1,2,4-oxadiazol-3-yl)piperidine hydrochloride chemical structure, C8H11ClF3N3O, CAS 1351499-82-5
4-(5-(Trifluoromethyl)-1,2,4-oxadiazol-3-yl)piperidine hydrochloride
CAS 1351499-82-5C8H11ClF3N3O
4-(5-Methoxymethyl-[1,2,4]oxadiazol-3-yl)-piperidine hydrochloride chemical structure, C9H16ClN3O2, CAS 1361115-48-1
4-(5-Methoxymethyl-[1,2,4]oxadiazol-3-yl)-piperidine hydrochloride
CAS 1361115-48-1C9H16ClN3O2
4-(1,2,4-Oxadiazol-3-yl)piperidine hydrochloride chemical structure, C7H12ClN3O, CAS 1384079-72-4
4-(1,2,4-Oxadiazol-3-yl)piperidine hydrochloride
CAS 1384079-72-4C7H12ClN3O
4-[5-(2,2,2-Trifluoroethyl)-1,2,4-oxadiazol-3-yl]piperidine hydrochloride chemical structure, C9H13ClF3N3O, CAS 1385696-75-2
4-[5-(2,2,2-Trifluoroethyl)-1,2,4-oxadiazol-3-yl]piperidine hydrochloride
CAS 1385696-75-2C9H13ClF3N3O
4-(5-tert-Butyl-1,2,4-oxadiazol-3-yl)piperidine hydrochloride chemical structure, C11H20ClN3O, CAS 1351502-90-3
4-(5-tert-Butyl-1,2,4-oxadiazol-3-yl)piperidine hydrochloride
CAS 1351502-90-3C11H20ClN3O
4-[5-(2-Methylpropyl)-1,2,4-oxadiazol-3-yl]piperidine hydrochloride chemical structure, C11H20ClN3O, CAS 1385696-60-5
4-[5-(2-Methylpropyl)-1,2,4-oxadiazol-3-yl]piperidine hydrochloride
CAS 1385696-60-5C11H20ClN3O
4-(5-Ethyl-1,2,4-oxadiazol-3-yl)piperidine hydrochloride chemical structure, C9H16ClN3O, CAS 1385696-66-1
4-(5-Ethyl-1,2,4-oxadiazol-3-yl)piperidine hydrochloride
CAS 1385696-66-1C9H16ClN3O