Murcko scaffold
Ring system with 2 rings and 11 atoms
38 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 11
- Chemicals
- 38
- With full pages
- 3
Scaffold SMILES
c1ccc(SCC2CC2)cc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 38 of 38 chemicals
![Benzene, 1-[(cyclopropylmethyl)thio]-2,4-dinitro- chemical structure, C10H10N2O4S, CAS 36635-41-3](/s/OVPOWGARGPOOLN-UHFFFAOYSA-N.svg)
Benzene, 1-[(cyclopropylmethyl)thio]-2,4-dinitro-
CAS 36635-41-3C10H10N2O4S
![1-[(Phenylthio)methyl]cyclopropanamine chemical structure, C10H13NS, CAS 437985-45-0](/s/HLWUFOCSWLFONY-UHFFFAOYSA-N.svg)
1-[(Phenylthio)methyl]cyclopropanamine
CAS 437985-45-0C10H13NS
![1-Chloro-4-[(1-chloro-2-cyclopropylpropan-2-yl)sulfanyl]benzene chemical structure, C12H14Cl2S, CAS 66949-06-2](/s/PQCUHZHCLMNAQR-UHFFFAOYSA-N.svg)
1-Chloro-4-[(1-chloro-2-cyclopropylpropan-2-yl)sulfanyl]benzene
CAS 66949-06-2C12H14Cl2S
(3-((Cyclopropylmethyl)thio)phenyl)boronic acid
CAS 1025746-82-0C10H13BO2S
![1,2-Benzenediamine, 4-[(cyclopropylmethyl)thio]-, hydrochloride (1:2) chemical structure, C10H16Cl2N2S, CAS 63667-18-5](/s/ZEQVGRKHVNISGR-UHFFFAOYSA-N.svg)
1,2-Benzenediamine, 4-[(cyclopropylmethyl)thio]-, hydrochloride (1:2)
CAS 63667-18-5C10H16Cl2N2S
![2-Nitro-4-[(2,2-dichloro-1-methylcyclopropyl)methyl]thioaniline chemical structure, C11H12Cl2N2O2S, CAS 68078-20-6](/s/ZMYXIJAWIUVTCI-UHFFFAOYSA-N.svg)
2-Nitro-4-[(2,2-dichloro-1-methylcyclopropyl)methyl]thioaniline
CAS 68078-20-6C11H12Cl2N2O2S
![4-Chloro-1-[(cyclopropylmethyl)sulfanyl]-2-nitrobenzene chemical structure, C10H10ClNO2S, CAS 60340-91-2](/s/FGGNCCIBCGZHEX-UHFFFAOYSA-N.svg)
4-Chloro-1-[(cyclopropylmethyl)sulfanyl]-2-nitrobenzene
CAS 60340-91-2C10H10ClNO2S
![4-{[(2,2-Dichlorocyclopropyl)methyl]sulfanyl}-2-nitroaniline chemical structure, C10H10Cl2N2O2S, CAS 64915-55-5](/s/NNZDCLXPJUSUQM-UHFFFAOYSA-N.svg)
4-{[(2,2-Dichlorocyclopropyl)methyl]sulfanyl}-2-nitroaniline
CAS 64915-55-5C10H10Cl2N2O2S
(3-Bromophenyl)(cyclopropylmethyl)sulfane
CAS 1000576-47-5C10H11BrS
![2-[(Cyclopropylmethyl)thio]benzoic acid chemical structure, C11H12O2S, CAS 1030420-72-4](/s/LNRPKWMVSWJSBL-UHFFFAOYSA-N.svg)
2-[(Cyclopropylmethyl)thio]benzoic acid
CAS 1030420-72-4C11H12O2S
4-((Cyclopropylmethyl)thio)benzoic acid
CAS 1155956-82-3C11H12O2S
5-Chloro-2-cyclopropylmethylsulfanyl-phenylamine
CAS 1154384-91-4C10H12ClNS
4-((Cyclopropylmethyl)sulfanyl)aniline
CAS 1156171-80-0C10H13NS
2,5-Dimethoxy-4-((cyclopropylmethyl)thio)phenethylamine
CAS 207740-27-0C14H21NO2S
![Benzenamine, 2-[[(2,2-dichlorocyclopropyl)methyl]thio]- chemical structure, C10H11Cl2NS, CAS 1146290-11-0](/s/ABBVLAQJFLFDOB-UHFFFAOYSA-N.svg)
Benzenamine, 2-[[(2,2-dichlorocyclopropyl)methyl]thio]-
CAS 1146290-11-0C10H11Cl2NS
4-(Cyclopropylmethylthio)phenylboronic acid
CAS 1217501-03-5C10H13BO2S
![Benzene, 1-bromo-4-[(cyclopropylmethyl)thio]- chemical structure, C10H11BrS, CAS 917382-54-8](/s/DGEUSHXVDCWKFE-UHFFFAOYSA-N.svg)
Benzene, 1-bromo-4-[(cyclopropylmethyl)thio]-
CAS 917382-54-8C10H11BrS
4-((Cyclopropylmethyl)thio)benzaldehyde
CAS 917382-97-9C11H12OS
![4-[(Cyclopropylmethyl)sulfanyl]phenol chemical structure, C10H12OS, CAS 1184488-81-0](/s/NHLMGZCDJPJOLA-UHFFFAOYSA-N.svg)
4-[(Cyclopropylmethyl)sulfanyl]phenol
CAS 1184488-81-0C10H12OS
3-((Cyclopropylmethyl)thio)benzoic acid
CAS 1427082-81-2C11H12O2S
1-(3-((Cyclopropylmethyl)thio)phenyl)ethanone
CAS 1343388-96-4C12H14OS
2-(1-((Phenylsulfanyl)methyl)cyclopropyl)acetic acid
CAS 1489830-03-6C12H14O2S
3-((Cyclopropylmethyl)thio)benzaldehyde
CAS 1508976-61-1C11H12OS
![1-[(Cyclopropylmethyl)sulfanyl]-4-nitrobenzene chemical structure, C10H11NO2S, CAS 1881321-19-2](/s/SKDCINKDFVMMND-UHFFFAOYSA-N.svg)
1-[(Cyclopropylmethyl)sulfanyl]-4-nitrobenzene
CAS 1881321-19-2C10H11NO2S
- 1-Chloro-4-[(cyclopropylmethyl)sulfanyl]benzene53911-83-4C10H11ClS
- 4-Chloro-3-[(cyclopropylmethyl)sulfanyl]aniline1511522-12-5C10H12ClNS
- 3-Cyclopropylmethylsulfanyl-phenylamine1510951-56-0C10H13NS
- Cyclopropyl[(3-fluorophenyl)sulfanyl]acetic acid1514971-38-0C11H11FO2S
- 2-[(2-Aminophenyl)sulfanyl]-2-cyclopropylpropanoic acid1247722-47-9C12H15NO2S
- Cyclopropanecarbonitrile, 1-[(phenylthio)methyl]-1387565-86-7C11H11NS
- 2,5-Dimethoxy-4-cyclopropylmethylthioamphetamine1313603-97-2C15H23NO2S
- 3-[(Cyclopropylmethyl)sulfanyl]phenol1394926-84-1C10H12OS
- Ethyl 2-[4-(cyclopropylmethylsulfanyl)phenyl]-2-oxoacetate1787260-79-0C14H16O3S
- 3-[(Cyclopropylmethyl)sulfanyl]-2,6-difluorobenzoic acid1864061-65-3C11H10F2O2S
- 1-[(Cyclopropylmethyl)sulfanyl]-3-nitrobenzene1881331-73-2C10H11NO2S
- 1-Chloro-3-[(cyclopropylmethyl)sulfanyl]benzene1863460-64-3C10H11ClS
- tert-Butyl N-(2-{[(2,2-dichlorocyclopropyl)methyl]sulfanyl}phenyl)carbamate2680899-34-5C15H19Cl2NO2S
- (Cyclopropylmethyl)(3-iodophenyl)sulfane1644246-55-8C10H11IS
Related scaffolds
Same ring framework with different atoms or bond orders
O=C(Nc1ccccc1)C1CC174 chemicals
c1ccc(OCC2CO2)cc157 chemicals
c1ccc(CNC2CC2)cc154 chemicals
O=C(NC1CC1)c1ccccc148 chemicals
c1ccc(OCC2CC2)cc138 chemicals
O=S(=O)(NC1CC1)c1ccccc135 chemicals
O=C(Cc1ccccc1)C1CC114 chemicals
c1ccc(NCC2CC2)cc111 chemicals
c1ccc(OCC2CC2)nc111 chemicals
c1ccc(CCC2CC2)cc19 chemicals
O=C(CC1CC1)c1ccccc17 chemicals
O=S(=O)(NC1CC1)c1cccnc14 chemicals