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Murcko scaffold

2-Thioxo-2,3,5,6-tetrahydrobenzo[h]quinazolin-4(1H)-one scaffold

8 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
16
Chemicals
8
With full pages
6
Scaffold SMILES

O=c1[nH]c(=S)[nH]c2c1CCc1ccccc1-2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-Thioxo-2,3,5,6-tetrahydrobenzo[h]quinazolin-4(1H)-one page
Murcko scaffold O=c1[nH]c(=S)[nH]c2c1CCc1ccccc1-2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 8 of 8 chemicals

3,5,5-Trimethyl-2-sulfanylidene-1,6-dihydrobenzo[h]quinazolin-4-one chemical structure, C15H16N2OS, CAS 312585-58-3
3,5,5-Trimethyl-2-sulfanylidene-1,6-dihydrobenzo[h]quinazolin-4-one
CAS 312585-58-3C15H16N2OS
5,5-Dimethyl-2-sulfanylidene-1,6-dihydrobenzo[h]quinazolin-4-one chemical structure, C14H14N2OS, CAS 303101-99-7
5,5-Dimethyl-2-sulfanylidene-1,6-dihydrobenzo[h]quinazolin-4-one
CAS 303101-99-7C14H14N2OS
5,5-Dimethyl-3-(2-methylprop-2-enyl)-2-sulfanylidene-1,6-dihydrobenzo[h]quinazolin-4-one chemical structure, C18H20N2OS, CAS 381184-28-7
5,5-Dimethyl-3-(2-methylprop-2-enyl)-2-sulfanylidene-1,6-dihydrobenzo[h]quinazolin-4-one
CAS 381184-28-7C18H20N2OS
3-Ethyl-5,5-dimethyl-2-sulfanylidene-1,6-dihydrobenzo[h]quinazolin-4-one chemical structure, C16H18N2OS, CAS 337496-59-0
3-Ethyl-5,5-dimethyl-2-sulfanylidene-1,6-dihydrobenzo[h]quinazolin-4-one
CAS 337496-59-0C16H18N2OS
5,5-Diethyl-2-thioxo-2,3,5,6-tetrahydrobenzo[h]quinazolin-4(1H)-one chemical structure, C16H18N2OS, CAS 371215-98-4
5,5-Diethyl-2-thioxo-2,3,5,6-tetrahydrobenzo[h]quinazolin-4(1H)-one
CAS 371215-98-4C16H18N2OS
5-Ethyl-5-methyl-2-sulfanylidene-1,6-dihydrobenzo[h]quinazolin-4-one chemical structure, C15H16N2OS, CAS 330180-73-9
5-Ethyl-5-methyl-2-sulfanylidene-1,6-dihydrobenzo[h]quinazolin-4-one
CAS 330180-73-9C15H16N2OS
5-Isopropyl-2-thioxo-2,3,5,6-tetrahydrobenzo[h]quinazolin-4(1H)-one chemical structure, C15H16N2OS, CAS 305858-68-8
5-Isopropyl-2-thioxo-2,3,5,6-tetrahydrobenzo[h]quinazolin-4(1H)-one
CAS 305858-68-8C15H16N2OS
2-Thioxo-2,3,5,6-tetrahydrobenzo[h]quinazolin-4(1H)-one chemical structure, C12H10N2OS, CAS 236093-41-7
2-Thioxo-2,3,5,6-tetrahydrobenzo[h]quinazolin-4(1H)-one
CAS 236093-41-7C12H10N2OS