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Murcko scaffold

4-(2-Thienyl)-1,2,3,6-tetrahydropyridine scaffold

17 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
11
Chemicals
17
With full pages
4
Scaffold SMILES

C1=C(c2cccs2)CCNC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 4-(2-Thienyl)-1,2,3,6-tetrahydropyridine page
Murcko scaffold C1=C(c2cccs2)CCNC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 17 of 17 chemicals

1-Methyl-4-(2-thienyl)-1,2,3,6-tetrahydropyridine chemical structure, C10H13NS, CAS 80353-09-9
1-Methyl-4-(2-thienyl)-1,2,3,6-tetrahydropyridine
CAS 80353-09-9C10H13NS
5-(2,2,6,6-Tetramethyl-1,2,3,6-tetrahydro-pyridin-4-yl)-thiophene-2-carboxylic acid chemical structure, C14H19NO2S, CAS 788811-22-3
5-(2,2,6,6-Tetramethyl-1,2,3,6-tetrahydro-pyridin-4-yl)-thiophene-2-carboxylic acid
CAS 788811-22-3C14H19NO2S
5-(2,2,6,6-Tetramethyl-1,2,3,6-tetrahydro-pyridin-4-yl)-thiophene-2-carbaldehyde chemical structure, C14H19NOS, CAS 99539-08-9
5-(2,2,6,6-Tetramethyl-1,2,3,6-tetrahydro-pyridin-4-yl)-thiophene-2-carbaldehyde
CAS 99539-08-9C14H19NOS
5-(2,2,6,6-Tetramethyl-1,2,3,6-tetrahydro-pyridin-4-yl)-thiophene-2-carboxylic acid hydrochloride chemical structure, C14H20ClNO2S, CAS 302354-29-6
5-(2,2,6,6-Tetramethyl-1,2,3,6-tetrahydro-pyridin-4-yl)-thiophene-2-carboxylic acid hydrochloride
CAS 302354-29-6C14H20ClNO2S
4-(2-Thienyl)-1,2,3,6-tetrahydropyridine chemical structure, C9H11NS, CAS 50461-50-2
4-(2-Thienyl)-1,2,3,6-tetrahydropyridine
CAS 50461-50-2C9H11NS
[4-(5-Formylthiophen-2-yl)-2,2,6,6-tetramethyl-3,6-dihydropyridin-1(2H)-yl]oxidanyl chemical structure, C14H18NO2S, CAS 99539-10-3
[4-(5-Formylthiophen-2-yl)-2,2,6,6-tetramethyl-3,6-dihydropyridin-1(2H)-yl]oxidanyl
CAS 99539-10-3C14H18NO2S
4-(Thiophen-2-yl)-1,2,3,6-tetrahydropyridine hydrochloride chemical structure, C9H12ClNS, CAS 93562-37-9
4-(Thiophen-2-yl)-1,2,3,6-tetrahydropyridine hydrochloride
CAS 93562-37-9C9H12ClNS
5-(1-(tert-Butoxycarbonyl)-1,2,3,6-tetrahydropyridin-4-yl)thiophene-2-carboxylic acid chemical structure, C15H19NO4S, CAS 849237-21-4
5-(1-(tert-Butoxycarbonyl)-1,2,3,6-tetrahydropyridin-4-yl)thiophene-2-carboxylic acid
CAS 849237-21-4C15H19NO4S
tert-Butyl 4-(4-methylthiophen-2-yl)-3,6-dihydropyridine-1(2H)-carboxylate chemical structure, C15H21NO2S, CAS 1266114-11-7
tert-Butyl 4-(4-methylthiophen-2-yl)-3,6-dihydropyridine-1(2H)-carboxylate
CAS 1266114-11-7C15H21NO2S
1-(tert-Butyl) 3-ethyl 4-(3-((tert-butoxycarbonyl)amino)thiophen-2-yl)-5,6-dihydropyridine-1,3(2H)-dicarboxylate chemical structure, C22H32N2O6S, CAS 1873332-44-5
1-(tert-Butyl) 3-ethyl 4-(3-((tert-butoxycarbonyl)amino)thiophen-2-yl)-5,6-dihydropyridine-1,3(2H)-dicarboxylate
CAS 1873332-44-5C22H32N2O6S
tert-Butyl 4-(4-bromothiophen-2-yl)-1,2,3,6-tetrahydropyridine-1-carboxylate chemical structure, C14H18BrNO2S, CAS 2059955-42-7
tert-Butyl 4-(4-bromothiophen-2-yl)-1,2,3,6-tetrahydropyridine-1-carboxylate
CAS 2059955-42-7C14H18BrNO2S
tert-Butyl 4-(5-chlorothiophen-2-yl)-3,6-dihydropyridine-1(2H)-carboxylate chemical structure, C14H18ClNO2S, CAS 2168547-45-1
tert-Butyl 4-(5-chlorothiophen-2-yl)-3,6-dihydropyridine-1(2H)-carboxylate
CAS 2168547-45-1C14H18ClNO2S
Methyl 4-bromo-5-(1,2,3,6-tetrahydropyridin-4-yl)thiophene-2-carboxylate chemical structure, C11H12BrNO2S, CAS 2137627-56-4
Methyl 4-bromo-5-(1,2,3,6-tetrahydropyridin-4-yl)thiophene-2-carboxylate
CAS 2137627-56-4C11H12BrNO2S
1-[5-(1,2,3,6-Tetrahydropyridin-4-yl)thiophen-2-yl]ethan-1-one chemical structure, C11H13NOS, CAS 1426302-14-8
1-[5-(1,2,3,6-Tetrahydropyridin-4-yl)thiophen-2-yl]ethan-1-one
CAS 1426302-14-8C11H13NOS
5-(1,2,3,6-Tetrahydropyridin-4-yl)thiophene-2-carboxylic acid chemical structure, C10H11NO2S, CAS 2137643-11-7
5-(1,2,3,6-Tetrahydropyridin-4-yl)thiophene-2-carboxylic acid
CAS 2137643-11-7C10H11NO2S
5-(1,2,3,6-Tetrahydropyridin-4-yl)thiophene-3-carbaldehyde chemical structure, C10H11NOS, CAS 2138352-41-5
5-(1,2,3,6-Tetrahydropyridin-4-yl)thiophene-3-carbaldehyde
CAS 2138352-41-5C10H11NOS
5-(1,2,3,6-Tetrahydropyridin-4-yl)thiophene-2-carbaldehyde chemical structure, C10H11NOS, CAS 2137581-12-3
5-(1,2,3,6-Tetrahydropyridin-4-yl)thiophene-2-carbaldehyde
CAS 2137581-12-3C10H11NOS