Murcko scaffold
Ring system with 2 rings and 14 atoms
43 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 14
- Chemicals
- 43
- With full pages
- 5
Scaffold SMILES
O=C(Nc1ccccc1)c1nncs1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 43 of 43 chemicals
5-(Chloromethyl)-N-phenyl-1,3,4-thiadiazole-2-carboxamide
CAS 113940-13-9C10H8ClN3OS
5-(Chloromethyl)-N-(4-chlorophenyl)-1,3,4-thiadiazole-2-carboxamide
CAS 875159-92-5C10H7Cl2N3OS
![Ethyl 5-{[(4-methoxyphenyl)amino]carbonyl}-1,3,4-thiadiazole-2-carboxylate chemical structure, C13H13N3O4S, CAS 743424-37-5](/s/KHVXPCXSWFYACB-UHFFFAOYSA-N.svg)
Ethyl 5-{[(4-methoxyphenyl)amino]carbonyl}-1,3,4-thiadiazole-2-carboxylate
CAS 743424-37-5C13H13N3O4S
5-(Chloromethyl)-N-(4-methylphenyl)-1,3,4-thiadiazole-2-carboxamide
CAS 113940-14-0C11H10ClN3OS
5-(Chloromethyl)-N-(4-methoxyphenyl)-1,3,4-thiadiazole-2-carboxamide
CAS 113940-15-1C11H10ClN3O2S
![3-(5-{[(4-Fluorophenyl)amino]carbonyl}-1,3,4-thiadiazol-2-yl)propanoic acid chemical structure, C12H10FN3O3S, CAS 1142202-61-6](/s/NSDRMXQRVFTZPH-UHFFFAOYSA-N.svg)
3-(5-{[(4-Fluorophenyl)amino]carbonyl}-1,3,4-thiadiazol-2-yl)propanoic acid
CAS 1142202-61-6C12H10FN3O3S
![3-(5-{[(3-Methoxyphenyl)amino]carbonyl}-1,3,4-thiadiazol-2-yl)propanoic acid chemical structure, C13H13N3O4S, CAS 1142202-63-8](/s/WWQUZTZUNMXSCY-UHFFFAOYSA-N.svg)
3-(5-{[(3-Methoxyphenyl)amino]carbonyl}-1,3,4-thiadiazol-2-yl)propanoic acid
CAS 1142202-63-8C13H13N3O4S
![3-(5-{[(4-Methylphenyl)amino]carbonyl}-1,3,4-thiadiazol-2-yl)propanoic acid chemical structure, C13H13N3O3S, CAS 1142202-66-1](/s/ORZFPHZLSHKBAT-UHFFFAOYSA-N.svg)
3-(5-{[(4-Methylphenyl)amino]carbonyl}-1,3,4-thiadiazol-2-yl)propanoic acid
CAS 1142202-66-1C13H13N3O3S
![3-(5-{[(2,4-Difluorophenyl)amino]carbonyl}-1,3,4-thiadiazol-2-yl)propanoic acid chemical structure, C12H9F2N3O3S, CAS 1142202-71-8](/s/WBIYOXJYXWIBMP-UHFFFAOYSA-N.svg)
3-(5-{[(2,4-Difluorophenyl)amino]carbonyl}-1,3,4-thiadiazol-2-yl)propanoic acid
CAS 1142202-71-8C12H9F2N3O3S
![3-(5-{[(2-Fluorophenyl)amino]carbonyl}-1,3,4-thiadiazol-2-yl)propanoic acid chemical structure, C12H10FN3O3S, CAS 1142202-72-9](/s/HWFNZIFXIBXUQY-UHFFFAOYSA-N.svg)
3-(5-{[(2-Fluorophenyl)amino]carbonyl}-1,3,4-thiadiazol-2-yl)propanoic acid
CAS 1142202-72-9C12H10FN3O3S
![[(5-{[(4-Methoxyphenyl)amino]carbonyl}-1,3,4-thiadiazol-2-yl)methoxy]acetic acid chemical structure, C13H13N3O5S, CAS 1142202-78-5](/s/MYYOSANFGDVIKO-UHFFFAOYSA-N.svg)
[(5-{[(4-Methoxyphenyl)amino]carbonyl}-1,3,4-thiadiazol-2-yl)methoxy]acetic acid
CAS 1142202-78-5C13H13N3O5S
![4-[5-(Anilinocarbonyl)-1,3,4-thiadiazol-2-yl]-butanoic acid chemical structure, C13H13N3O3S, CAS 1142202-80-9](/s/XCTGVXVKTZPJIM-UHFFFAOYSA-N.svg)
4-[5-(Anilinocarbonyl)-1,3,4-thiadiazol-2-yl]-butanoic acid
CAS 1142202-80-9C13H13N3O3S
![[(5-{[(3-Fluorophenyl)amino]carbonyl}-1,3,4-thiadiazol-2-yl)methoxy]acetic acid chemical structure, C12H10FN3O4S, CAS 1142202-81-0](/s/CHDRUARJHSCLKB-UHFFFAOYSA-N.svg)
[(5-{[(3-Fluorophenyl)amino]carbonyl}-1,3,4-thiadiazol-2-yl)methoxy]acetic acid
CAS 1142202-81-0C12H10FN3O4S
![{[(5-{[(4-Methoxyphenyl)amino]carbonyl}-1,3,4-thiadiazol-2-yl)methyl]thio}acetic acid chemical structure, C13H13N3O4S2, CAS 1142202-88-7](/s/ITCGFFIITWXKDH-UHFFFAOYSA-N.svg)
{[(5-{[(4-Methoxyphenyl)amino]carbonyl}-1,3,4-thiadiazol-2-yl)methyl]thio}acetic acid
CAS 1142202-88-7C13H13N3O4S2
![4-(5-{[(3-Fluorophenyl)amino]carbonyl}-1,3,4-thiadiazol-2-yl)butanoic acid chemical structure, C13H12FN3O3S, CAS 1142202-89-8](/s/KJDVLIBDLUMZFR-UHFFFAOYSA-N.svg)
4-(5-{[(3-Fluorophenyl)amino]carbonyl}-1,3,4-thiadiazol-2-yl)butanoic acid
CAS 1142202-89-8C13H12FN3O3S
![3-(5-{[(3-Methylphenyl)amino]carbonyl}-1,3,4-thiadiazol-2-yl)propanoic acid chemical structure, C13H13N3O3S, CAS 1142209-36-6](/s/QRRORNSZZSWZOF-UHFFFAOYSA-N.svg)
3-(5-{[(3-Methylphenyl)amino]carbonyl}-1,3,4-thiadiazol-2-yl)propanoic acid
CAS 1142209-36-6C13H13N3O3S
![3-(5-{[(3,4-Difluorophenyl)amino]carbonyl}-1,3,4-thiadiazol-2-yl)propanoic acid chemical structure, C12H9F2N3O3S, CAS 1142209-39-9](/s/GIVJPUGMAKLECN-UHFFFAOYSA-N.svg)
3-(5-{[(3,4-Difluorophenyl)amino]carbonyl}-1,3,4-thiadiazol-2-yl)propanoic acid
CAS 1142209-39-9C12H9F2N3O3S
![3-(5-{[(3-Chlorophenyl)amino]carbonyl}-1,3,4-thiadiazol-2-yl)propanoic acid chemical structure, C12H10ClN3O3S, CAS 1142209-40-2](/s/PUVMOZJWRCQEFG-UHFFFAOYSA-N.svg)
3-(5-{[(3-Chlorophenyl)amino]carbonyl}-1,3,4-thiadiazol-2-yl)propanoic acid
CAS 1142209-40-2C12H10ClN3O3S
![3-[5-(Anilinocarbonyl)-1,3,4-thiadiazol-2-yl]-propanoic acid chemical structure, C12H11N3O3S, CAS 1142209-41-3](/s/CFBBVAKTGBLVAN-UHFFFAOYSA-N.svg)
3-[5-(Anilinocarbonyl)-1,3,4-thiadiazol-2-yl]-propanoic acid
CAS 1142209-41-3C12H11N3O3S
![4-(5-{[(3-Chlorophenyl)amino]carbonyl}-1,3,4-thiadiazol-2-yl)butanoic acid chemical structure, C13H12ClN3O3S, CAS 1142209-51-5](/s/SYRJWSLECOXZJB-UHFFFAOYSA-N.svg)
4-(5-{[(3-Chlorophenyl)amino]carbonyl}-1,3,4-thiadiazol-2-yl)butanoic acid
CAS 1142209-51-5C13H12ClN3O3S
![3-(5-{[(4-Methoxyphenyl)amino]carbonyl}-1,3,4-thiadiazol-2-yl)propanoic acid chemical structure, C13H13N3O4S, CAS 1142209-61-7](/s/FJHAGTCXQAQHGQ-UHFFFAOYSA-N.svg)
3-(5-{[(4-Methoxyphenyl)amino]carbonyl}-1,3,4-thiadiazol-2-yl)propanoic acid
CAS 1142209-61-7C13H13N3O4S
![[(5-{[(4-Methylphenyl)amino]carbonyl}-1,3,4-thiadiazol-2-yl)methoxy]acetic acid chemical structure, C13H13N3O4S, CAS 1142209-62-8](/s/BNDOPSISRWKAHQ-UHFFFAOYSA-N.svg)
[(5-{[(4-Methylphenyl)amino]carbonyl}-1,3,4-thiadiazol-2-yl)methoxy]acetic acid
CAS 1142209-62-8C13H13N3O4S
![{[(5-{[(4-Methylphenyl)amino]carbonyl}-1,3,4-thiadiazol-2-yl)methyl]thio}acetic acid chemical structure, C13H13N3O3S2, CAS 1142209-64-0](/s/HIONPDKCQKGNOO-UHFFFAOYSA-N.svg)
{[(5-{[(4-Methylphenyl)amino]carbonyl}-1,3,4-thiadiazol-2-yl)methyl]thio}acetic acid
CAS 1142209-64-0C13H13N3O3S2
![4-(5-{[(4-Methylphenyl)amino]carbonyl}-1,3,4-thiadiazol-2-yl)butanoic acid chemical structure, C14H15N3O3S, CAS 1142209-67-3](/s/PXYKWRGUEYUEOR-UHFFFAOYSA-N.svg)
4-(5-{[(4-Methylphenyl)amino]carbonyl}-1,3,4-thiadiazol-2-yl)butanoic acid
CAS 1142209-67-3C14H15N3O3S
- {[(5-{[(3-Fluorophenyl)amino]carbonyl}-1,3,4-thiadiazol-2-yl)methyl]thio}acetic acid1142209-68-4C12H10FN3O3S2
- [(5-{[(3-Chlorophenyl)amino]carbonyl}-1,3,4-thiadiazol-2-yl)methoxy]acetic acid1142209-70-8C12H10ClN3O4S
- Ethyl 5-{[(3-chlorophenyl)amino]carbonyl}-1,3,4-thiadiazole-2-carboxylate1142209-74-2C12H10ClN3O3S
- {[(5-{[(2-Methylphenyl)amino]carbonyl}-1,3,4-thiadiazol-2-yl)methyl]thio}acetic acid1142209-76-4C13H13N3O3S2
- ({[5-({[4-(Ethoxycarbonyl)phenyl]amino}carbonyl)-1,3,4-thiadiazol-2-yl]methyl}thio)acetic acid1142209-96-8C15H15N3O5S2
- 4-(5-{[(2-Methylphenyl)amino]carbonyl}-1,3,4-thiadiazol-2-yl)butanoic acid1142210-01-2C14H15N3O3S
- 3-(5-{[(2-Methylphenyl)amino]carbonyl}-1,3,4-thiadiazol-2-yl)propanoic acid1142210-07-8C13H13N3O3S
- 4-(5-{[(4-Methoxyphenyl)amino]carbonyl}-1,3,4-thiadiazol-2-yl)butanoic acid1142210-57-8C14H15N3O4S
- Ethyl 5-{[(4-chlorophenyl)amino]carbonyl}-1,3,4-thiadiazole-2-carboxylate1142210-64-7C12H10ClN3O3S
- Ethyl 5-{[(4-fluorophenyl)amino]carbonyl}-1,3,4-thiadiazole-2-carboxylate1142210-68-1C12H10FN3O3S
- Ethyl 5-{[(4-methylphenyl)amino]carbonyl}-1,3,4-thiadiazole-2-carboxylate1142210-74-9C13H13N3O3S
- 5-(Chloromethyl)-N-(4-fluorophenyl)-1,3,4-thiadiazole-2-carboxamide949393-05-9C10H7ClFN3OS
- 5-(Chloromethyl)-N-(4-ethylphenyl)-1,3,4-thiadiazole-2-carboxamide1087792-49-1C12H12ClN3OS
- 5-(Aminomethyl)-N-(2-fluorophenyl)-1,3,4-thiadiazole-2-carboxamide1217862-37-7C10H9FN4OS
- 5-(Aminomethyl)-N-(2,4-difluorophenyl)-1,3,4-thiadiazole-2-carboxamide1217862-93-5C10H8F2N4OS
- 5-(Aminomethyl)-N-phenyl-1,3,4-thiadiazole-2-carboxamide1217862-67-3C10H10N4OS
- 5-(Aminomethyl)-N-(4-methylphenyl)-1,3,4-thiadiazole-2-carboxamide1217862-94-6C11H12N4OS
- 5-(Aminomethyl)-N-(4-fluorophenyl)-1,3,4-thiadiazole-2-carboxamide1217862-69-5C10H9FN4OS
- [(5-{[(3-Chlorophenyl)amino]carbonyl}-1,3,4-thiadiazol-2-yl)thio]acetic acid1242951-47-8C11H8ClN3O3S2
Related scaffolds
Same ring framework with different atoms or bond orders
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