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Murcko scaffold

Ring system with 4 rings and 20 atoms

13 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
20
Chemicals
13
With full pages
2
Scaffold SMILES

c1ccc(Cc2ccc3nc4ccccc4n3c2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(Cc2ccc3nc4ccccc4n3c2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 13 of 13 chemicals

2-Benzyl-1-chloro-3-methylpyrido[1,2-a]benzimidazole-4-carbonitrile chemical structure, C20H14ClN3, CAS 121105-86-0
2-Benzyl-1-chloro-3-methylpyrido[1,2-a]benzimidazole-4-carbonitrile
CAS 121105-86-0C20H14ClN3
2-Benzyl-1-[2-(dimethylamino)ethylamino]-3-methylpyrido[1,2-a]benzimidazole-4-carbonitrile chemical structure, C24H25N5, CAS 305332-64-3
2-Benzyl-1-[2-(dimethylamino)ethylamino]-3-methylpyrido[1,2-a]benzimidazole-4-carbonitrile
CAS 305332-64-3C24H25N5
1-Chloro-2-(4-chlorobenzyl)-3-methylpyrido[1,2-a]benzimidazole-4-carbonitrile chemical structure, C20H13Cl2N3, CAS 459181-43-2
1-Chloro-2-(4-chlorobenzyl)-3-methylpyrido[1,2-a]benzimidazole-4-carbonitrile
CAS 459181-43-2C20H13Cl2N3
1-Chloro-3-methyl-2-(4-methylbenzyl)pyrido[1,2-a]benzimidazole-4-carbonitrile chemical structure, C21H16ClN3, CAS 862106-12-5
1-Chloro-3-methyl-2-(4-methylbenzyl)pyrido[1,2-a]benzimidazole-4-carbonitrile
CAS 862106-12-5C21H16ClN3
1-Chloro-3-methyl-2-(2-methylbenzyl)pyrido[1,2-a]benzimidazole-4-carbonitrile chemical structure, C21H16ClN3, CAS 848994-68-3
1-Chloro-3-methyl-2-(2-methylbenzyl)pyrido[1,2-a]benzimidazole-4-carbonitrile
CAS 848994-68-3C21H16ClN3
2-Benzyl-3-methyl-1-(undecylamino)pyrido[1,2-a]benzimidazole-4-carbonitrile chemical structure, C31H38N4, CAS 305334-40-1
2-Benzyl-3-methyl-1-(undecylamino)pyrido[1,2-a]benzimidazole-4-carbonitrile
CAS 305334-40-1C31H38N4
2-Benzyl-1-[(3-ethoxypropyl)amino]-3-methylpyrido[1,2-a]benzimidazole-4-carbonitrile chemical structure, C25H26N4O, CAS 331868-01-0
2-Benzyl-1-[(3-ethoxypropyl)amino]-3-methylpyrido[1,2-a]benzimidazole-4-carbonitrile
CAS 331868-01-0C25H26N4O
1-{[2-(Dimethylamino)ethyl]amino}-3-methyl-2-(4-methylbenzyl)pyrido[1,2-a]benzimidazole-4-carbonitrile chemical structure, C25H27N5, CAS 849827-19-6
1-{[2-(Dimethylamino)ethyl]amino}-3-methyl-2-(4-methylbenzyl)pyrido[1,2-a]benzimidazole-4-carbonitrile
CAS 849827-19-6C25H27N5
2-(2-Chlorobenzyl)-1-[(2-methoxyethyl)amino]-3-methylpyrido[1,2-a]benzimidazole-4-carbonitrile chemical structure, C23H21ClN4O, CAS 848930-97-2
2-(2-Chlorobenzyl)-1-[(2-methoxyethyl)amino]-3-methylpyrido[1,2-a]benzimidazole-4-carbonitrile
CAS 848930-97-2C23H21ClN4O
13-{[3-(Dimethylamino)propyl]amino}-11-methyl-12-[(4-methylphenyl)methyl]-1,8-diazatricyclo[7.4.0.0^{2,7}]trideca-2(7),3,5,8,10,12-hexaene-10-carbonitrile chemical structure, C26H29N5, CAS 848930-68-7
13-{[3-(Dimethylamino)propyl]amino}-11-methyl-12-[(4-methylphenyl)methyl]-1,8-diazatricyclo[7.4.0.0^{2,7}]trideca-2(7),3,5,8,10,12-hexaene-10-carbonitrile
CAS 848930-68-7C26H29N5
1-(2-Methoxyethylamino)-3-methyl-2-[(4-methylphenyl)methyl]pyrido[1,2-a]benzimidazole-4-carbonitrile chemical structure, C24H24N4O, CAS 848922-55-4
1-(2-Methoxyethylamino)-3-methyl-2-[(4-methylphenyl)methyl]pyrido[1,2-a]benzimidazole-4-carbonitrile
CAS 848922-55-4C24H24N4O
2-(4-Chlorobenzyl)-1-{[3-(dimethylamino)propyl]amino}-3-methylpyrido[1,2-a]benzimidazole-4-carbonitrile chemical structure, C25H26ClN5, CAS 443332-39-6
2-(4-Chlorobenzyl)-1-{[3-(dimethylamino)propyl]amino}-3-methylpyrido[1,2-a]benzimidazole-4-carbonitrile
CAS 443332-39-6C25H26ClN5
12-[(2-Chlorophenyl)methyl]-13-{[2-(dimethylamino)ethyl]amino}-11-methyl-1,8-diazatricyclo[7.4.0.0^{2,7}]trideca-2(7),3,5,8,10,12-hexaene-10-carbonitrile chemical structure, C24H24ClN5, CAS 868153-15-5
12-[(2-Chlorophenyl)methyl]-13-{[2-(dimethylamino)ethyl]amino}-11-methyl-1,8-diazatricyclo[7.4.0.0^{2,7}]trideca-2(7),3,5,8,10,12-hexaene-10-carbonitrile
CAS 868153-15-5C24H24ClN5