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Murcko scaffold

N-Benzyl-2-(2,4-dioxo-1,3-diazaspiro[4.5]decan-3-yl)acetamide scaffold

23 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
23
Chemicals
23
With full pages
14
Scaffold SMILES

O=C(CN1C(=O)NC2(CCCCC2)C1=O)NCc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the N-Benzyl-2-(2,4-dioxo-1,3-diazaspiro[4.5]decan-3-yl)acetamide page
Murcko scaffold O=C(CN1C(=O)NC2(CCCCC2)C1=O)NCc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 23 of 23 chemicals

N-(4-Fluorobenzyl)-2-(8-methyl-2,4-dioxo-1,3-diazaspiro[4.5]dec-3-yl)acetamide chemical structure, C18H22FN3O3, CAS 784197-76-8
N-(4-Fluorobenzyl)-2-(8-methyl-2,4-dioxo-1,3-diazaspiro[4.5]dec-3-yl)acetamide
CAS 784197-76-8C18H22FN3O3
2-(2,4-Dioxo-1,3-diazaspiro[4.5]dec-3-yl)-N-(4-methoxybenzyl)acetamide chemical structure, C18H23N3O4, CAS 784161-89-3
2-(2,4-Dioxo-1,3-diazaspiro[4.5]dec-3-yl)-N-(4-methoxybenzyl)acetamide
CAS 784161-89-3C18H23N3O4
N-[(4-Chlorophenyl)methyl]-2-(8-methyl-2,4-dioxo-1,3-diazaspiro[4.5]decan-3-yl)acetamide chemical structure, C18H22ClN3O3, CAS 722459-05-4
N-[(4-Chlorophenyl)methyl]-2-(8-methyl-2,4-dioxo-1,3-diazaspiro[4.5]decan-3-yl)acetamide
CAS 722459-05-4C18H22ClN3O3
N-[(4-Chlorophenyl)methyl]-2-(8-ethyl-2,4-dioxo-1,3-diazaspiro[4.5]decan-3-yl)acetamide chemical structure, C19H24ClN3O3, CAS 565436-67-1
N-[(4-Chlorophenyl)methyl]-2-(8-ethyl-2,4-dioxo-1,3-diazaspiro[4.5]decan-3-yl)acetamide
CAS 565436-67-1C19H24ClN3O3
N-Benzyl-2-(8-methyl-2,4-dioxo-1,3-diazaspiro[4.5]dec-3-yl)acetamide chemical structure, C18H23N3O3, CAS 571159-45-0
N-Benzyl-2-(8-methyl-2,4-dioxo-1,3-diazaspiro[4.5]dec-3-yl)acetamide
CAS 571159-45-0C18H23N3O3
2-(2,4-Dioxo-1,3-diazaspiro[4.5]dec-3-yl)-N-(4-methylbenzyl)acetamide chemical structure, C18H23N3O3, CAS 781619-57-6
2-(2,4-Dioxo-1,3-diazaspiro[4.5]dec-3-yl)-N-(4-methylbenzyl)acetamide
CAS 781619-57-6C18H23N3O3
N-[(2-Chlorophenyl)methyl]-2-(8-ethyl-2,4-dioxo-1,3-diazaspiro[4.5]decan-3-yl)acetamide chemical structure, C19H24ClN3O3, CAS 771497-37-1
N-[(2-Chlorophenyl)methyl]-2-(8-ethyl-2,4-dioxo-1,3-diazaspiro[4.5]decan-3-yl)acetamide
CAS 771497-37-1C19H24ClN3O3
N-Benzyl-2-(2,4-dioxo-1,3-diazaspiro[4.5]decan-3-yl)acetamide chemical structure, C17H21N3O3, CAS 849823-54-7
N-Benzyl-2-(2,4-dioxo-1,3-diazaspiro[4.5]decan-3-yl)acetamide
CAS 849823-54-7C17H21N3O3
2-(6-Methyl-2,4-dioxo-1,3-diazaspiro[4.5]decan-3-yl)-N-(4-methylbenzyl)acetamide chemical structure, C19H25N3O3, CAS 771501-68-9
2-(6-Methyl-2,4-dioxo-1,3-diazaspiro[4.5]decan-3-yl)-N-(4-methylbenzyl)acetamide
CAS 771501-68-9C19H25N3O3
N-[(4-Fluorophenyl)methyl]-2-{6-methyl-2,4-dioxo-1,3-diazaspiro[4.5]decan-3-yl}acetamide chemical structure, C18H22FN3O3, CAS 561050-11-1
N-[(4-Fluorophenyl)methyl]-2-{6-methyl-2,4-dioxo-1,3-diazaspiro[4.5]decan-3-yl}acetamide
CAS 561050-11-1C18H22FN3O3
N-(2-Chlorobenzyl)-2-(2,4-dioxo-1,3-diazaspiro[4.5]dec-3-yl)acetamide chemical structure, C17H20ClN3O3, CAS 734539-93-6
N-(2-Chlorobenzyl)-2-(2,4-dioxo-1,3-diazaspiro[4.5]dec-3-yl)acetamide
CAS 734539-93-6C17H20ClN3O3
2-(8-Methyl-2,4-dioxo-1,3-diazaspiro[4.5]dec-3-yl)-N-(1-phenylethyl)acetamide chemical structure, C19H25N3O3, CAS 1009671-47-9
2-(8-Methyl-2,4-dioxo-1,3-diazaspiro[4.5]dec-3-yl)-N-(1-phenylethyl)acetamide
CAS 1009671-47-9C19H25N3O3
N-(4-Methylbenzyl)-2-(8-methyl-2,4-dioxo-1,3-diazaspiro[4.5]dec-3-yl)acetamide chemical structure, C19H25N3O3, CAS 849617-70-5
N-(4-Methylbenzyl)-2-(8-methyl-2,4-dioxo-1,3-diazaspiro[4.5]dec-3-yl)acetamide
CAS 849617-70-5C19H25N3O3
2-(2,4-Dioxo-1,3-diazaspiro[4.5]dec-3-yl)-N-(1-phenylethyl)acetamide chemical structure, C18H23N3O3, CAS 850371-14-1
2-(2,4-Dioxo-1,3-diazaspiro[4.5]dec-3-yl)-N-(1-phenylethyl)acetamide
CAS 850371-14-1C18H23N3O3
2-(2,4-Dioxo-1,3-diazaspiro[4.5]dec-3-yl)-N-(3-methoxybenzyl)acetamide chemical structure, C18H23N3O4, CAS 923193-68-4
2-(2,4-Dioxo-1,3-diazaspiro[4.5]dec-3-yl)-N-(3-methoxybenzyl)acetamide
CAS 923193-68-4C18H23N3O4
N-Benzyl-2-(1-methyl-2,4-dioxo-1,3-diazaspiro[4.5]dec-3-yl)acetamide chemical structure, C18H23N3O3, CAS 923691-61-6
N-Benzyl-2-(1-methyl-2,4-dioxo-1,3-diazaspiro[4.5]dec-3-yl)acetamide
CAS 923691-61-6C18H23N3O3
N-(2-Methoxybenzyl)-2-(1-methyl-2,4-dioxo-1,3-diazaspiro[4.5]dec-3-yl)acetamide chemical structure, C19H25N3O4, CAS 875623-10-2
N-(2-Methoxybenzyl)-2-(1-methyl-2,4-dioxo-1,3-diazaspiro[4.5]dec-3-yl)acetamide
CAS 875623-10-2C19H25N3O4
N-(3,4-Dimethoxybenzyl)-2-(1-methyl-2,4-dioxo-1,3-diazaspiro[4.5]dec-3-yl)acetamide chemical structure, C20H27N3O5, CAS 1111444-66-6
N-(3,4-Dimethoxybenzyl)-2-(1-methyl-2,4-dioxo-1,3-diazaspiro[4.5]dec-3-yl)acetamide
CAS 1111444-66-6C20H27N3O5
N-Benzyl-N-methyl-2-(1-methyl-2,4-dioxo-1,3-diazaspiro[4.5]dec-3-yl)acetamide chemical structure, C19H25N3O3, CAS 1190569-92-6
N-Benzyl-N-methyl-2-(1-methyl-2,4-dioxo-1,3-diazaspiro[4.5]dec-3-yl)acetamide
CAS 1190569-92-6C19H25N3O3
N-(2-Fluorobenzyl)-2-(8-methyl-2,4-dioxo-1,3-diazaspiro[4.5]dec-3-yl)acetamide chemical structure, C18H22FN3O3, CAS 1190556-72-9
N-(2-Fluorobenzyl)-2-(8-methyl-2,4-dioxo-1,3-diazaspiro[4.5]dec-3-yl)acetamide
CAS 1190556-72-9C18H22FN3O3
2-(2,4-Dioxo-1,3-diazaspiro[4.5]dec-3-yl)-N-(2-fluorobenzyl)acetamide chemical structure, C17H20FN3O3, CAS 1181909-68-1
2-(2,4-Dioxo-1,3-diazaspiro[4.5]dec-3-yl)-N-(2-fluorobenzyl)acetamide
CAS 1181909-68-1C17H20FN3O3
2-{8-tert-Butyl-2,4-dioxo-1,3-diazaspiro[4.5]decan-3-YL}-N-[(2,3-dimethoxyphenyl)methyl]acetamide chemical structure, C23H33N3O5, CAS 1574637-73-2
2-{8-tert-Butyl-2,4-dioxo-1,3-diazaspiro[4.5]decan-3-YL}-N-[(2,3-dimethoxyphenyl)methyl]acetamide
CAS 1574637-73-2C23H33N3O5
2-(2,4-Dioxo-1,3-diazaspiro[4.5]dec-3-yl)-N-[1-(4-methylphenyl)ethyl]acetamide chemical structure, C19H25N3O3, CAS 1574586-95-0
2-(2,4-Dioxo-1,3-diazaspiro[4.5]dec-3-yl)-N-[1-(4-methylphenyl)ethyl]acetamide
CAS 1574586-95-0C19H25N3O3