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Murcko scaffold

Ring system with 3 rings and 16 atoms

29 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
16
Chemicals
29
With full pages
14
Scaffold SMILES

c1ccc(Nc2ccnc3ncnn23)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(Nc2ccnc3ncnn23)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 29 of 29 chemicals

N-(3-Chlorophenyl)-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine chemical structure, C12H10ClN5, CAS 104997-66-2
N-(3-Chlorophenyl)-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine
CAS 104997-66-2C12H10ClN5
N-(4-Methoxyphenyl)-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine chemical structure, C13H13N5O, CAS 91769-08-3
N-(4-Methoxyphenyl)-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine
CAS 91769-08-3C13H13N5O
N-(3-Fluoro-4-methylphenyl)-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine chemical structure, C13H12FN5, CAS 606136-23-6
N-(3-Fluoro-4-methylphenyl)-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine
CAS 606136-23-6C13H12FN5
5-Methyl-N-(4-methylphenyl)-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine chemical structure, C13H13N5, CAS 334507-31-2
5-Methyl-N-(4-methylphenyl)-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine
CAS 334507-31-2C13H13N5
N-(4-Chlorophenyl)-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine chemical structure, C12H10ClN5, CAS 330850-37-8
N-(4-Chlorophenyl)-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine
CAS 330850-37-8C12H10ClN5
N-(2-Ethylphenyl)-5-methyl[1,2,4]triazolo[1,5-a]pyrimidin-7-amine chemical structure, C14H15N5, CAS 334507-35-6
N-(2-Ethylphenyl)-5-methyl[1,2,4]triazolo[1,5-a]pyrimidin-7-amine
CAS 334507-35-6C14H15N5
4-((5-Methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl)amino)benzoic acid chemical structure, C13H11N5O2, CAS 330850-44-7
4-((5-Methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl)amino)benzoic acid
CAS 330850-44-7C13H11N5O2
5-Methyl-N-(3-methylphenyl)[1,2,4]triazolo[1,5-a]pyrimidin-7-amine chemical structure, C13H13N5, CAS 312620-37-4
5-Methyl-N-(3-methylphenyl)[1,2,4]triazolo[1,5-a]pyrimidin-7-amine
CAS 312620-37-4C13H13N5
2-(5-Methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-ylamino)-benzoic acid chemical structure, C13H11N5O2, CAS 392739-38-7
2-(5-Methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-ylamino)-benzoic acid
CAS 392739-38-7C13H11N5O2
1-[4-[(5-Methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl)amino]phenyl]ethanone chemical structure, C14H13N5O, CAS 312620-38-5
1-[4-[(5-Methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl)amino]phenyl]ethanone
CAS 312620-38-5C14H13N5O
N-(3-Chloro-4-methoxyphenyl)-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine chemical structure, C13H12ClN5O, CAS 330850-42-5
N-(3-Chloro-4-methoxyphenyl)-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine
CAS 330850-42-5C13H12ClN5O
N-(3,4-Dimethylphenyl)-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine chemical structure, C14H15N5, CAS 309738-86-1
N-(3,4-Dimethylphenyl)-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine
CAS 309738-86-1C14H15N5
N-(4-Fluorophenyl)-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine chemical structure, C12H10FN5, CAS 312620-43-2
N-(4-Fluorophenyl)-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine
CAS 312620-43-2C12H10FN5
N-(4-Fluorophenyl)-5-methyl-2-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine chemical structure, C13H9F4N5, CAS 900296-94-8
N-(4-Fluorophenyl)-5-methyl-2-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine
CAS 900296-94-8C13H9F4N5
N-(4-Chlorophenyl)-5-methyl-2-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine chemical structure, C13H9ClF3N5, CAS 900886-29-5
N-(4-Chlorophenyl)-5-methyl-2-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine
CAS 900886-29-5C13H9ClF3N5
N-[4-Chloro-3-(trifluoromethyl)phenyl]-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine chemical structure, C13H9ClF3N5, CAS 898479-12-4
N-[4-Chloro-3-(trifluoromethyl)phenyl]-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine
CAS 898479-12-4C13H9ClF3N5
N-(3-Chloro-4-methylphenyl)-5-methyl-2-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine chemical structure, C14H11ClF3N5, CAS 890622-16-9
N-(3-Chloro-4-methylphenyl)-5-methyl-2-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine
CAS 890622-16-9C14H11ClF3N5
N-(4-tert-Butylphenyl)-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine chemical structure, C16H19N5, CAS 874010-42-1
N-(4-tert-Butylphenyl)-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine
CAS 874010-42-1C16H19N5
N-(2-Chlorophenyl)-2-ethyl-5-methyl[1,2,4]triazolo[1,5-a]pyrimidin-7-amine chemical structure, C14H14ClN5, CAS 900315-26-6
N-(2-Chlorophenyl)-2-ethyl-5-methyl[1,2,4]triazolo[1,5-a]pyrimidin-7-amine
CAS 900315-26-6C14H14ClN5
N-(4-((5-Methyl-2-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl)amino)phenyl)acetamide chemical structure, C15H13F3N6O, CAS 946359-74-6
N-(4-((5-Methyl-2-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl)amino)phenyl)acetamide
CAS 946359-74-6C15H13F3N6O
N-(3,5-Dimethylphenyl)-5-methyl-2-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine chemical structure, C15H14F3N5, CAS 946359-78-0
N-(3,5-Dimethylphenyl)-5-methyl-2-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine
CAS 946359-78-0C15H14F3N5
Dsm-74 chemical structure, C13H10F3N5, CAS 898743-92-5
Dsm-74
CAS 898743-92-5C13H10F3N5
4-({5-Methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl}amino)-2-(trifluoromethyl)benzonitrile chemical structure, C14H9F3N6, CAS 1141892-64-9
4-({5-Methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl}amino)-2-(trifluoromethyl)benzonitrile
CAS 1141892-64-9C14H9F3N6
5-Methyl-N-[4-(2,2,2-trifluoroethyl)phenyl]-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine chemical structure, C14H12F3N5, CAS 1281860-82-9
5-Methyl-N-[4-(2,2,2-trifluoroethyl)phenyl]-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine
CAS 1281860-82-9C14H12F3N5