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Murcko scaffold

Ring system with 3 rings and 16 atoms

144 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
16
Chemicals
144
With full pages
16
Scaffold SMILES

c1ccc(Nc2ncnc3sccc23)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(Nc2ncnc3sccc23)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 144 chemicals

2-Methyl-N-(2-methylphenyl)thieno(2,3-d)pyrimidin-4-amine chemical structure, C14H13N3S, CAS 81102-91-2
2-Methyl-N-(2-methylphenyl)thieno(2,3-d)pyrimidin-4-amine
CAS 81102-91-2C14H13N3S
N-(2-Chlorophenyl)-2-methylthieno[2,3-d]pyrimidin-4-amine chemical structure, C13H10ClN3S, CAS 81102-92-3
N-(2-Chlorophenyl)-2-methylthieno[2,3-d]pyrimidin-4-amine
CAS 81102-92-3C13H10ClN3S
AG-690/33487030 chemical structure, C14H11Cl2N3S, CAS 5227-74-7
AG-690/33487030
CAS 5227-74-7C14H11Cl2N3S
N-(4-Fluorophenyl)-5,6-dimethylthieno[2,3-d]pyrimidin-4-amine chemical structure, C14H12FN3S, CAS 453583-40-9
N-(4-Fluorophenyl)-5,6-dimethylthieno[2,3-d]pyrimidin-4-amine
CAS 453583-40-9C14H12FN3S
N-(4-Ethoxyphenyl)-5,6-dimethylthieno[2,3-d]pyrimidin-4-amine chemical structure, C16H17N3OS, CAS 423145-24-8
N-(4-Ethoxyphenyl)-5,6-dimethylthieno[2,3-d]pyrimidin-4-amine
CAS 423145-24-8C16H17N3OS
4-[(5,6-Dimethylthieno[2,3-d]pyrimidin-4-yl)amino]phenol chemical structure, C14H13N3OS, CAS 799800-65-0
4-[(5,6-Dimethylthieno[2,3-d]pyrimidin-4-yl)amino]phenol
CAS 799800-65-0C14H13N3OS
N-(2-Methoxyphenyl)-5,6-dimethylthieno[2,3-d]pyrimidin-4-amine chemical structure, C15H15N3OS, CAS 314021-94-8
N-(2-Methoxyphenyl)-5,6-dimethylthieno[2,3-d]pyrimidin-4-amine
CAS 314021-94-8C15H15N3OS
N-(2-Fluorophenyl)-5,6-dimethylthieno[2,3-d]pyrimidin-4-amine chemical structure, C14H12FN3S, CAS 345616-09-3
N-(2-Fluorophenyl)-5,6-dimethylthieno[2,3-d]pyrimidin-4-amine
CAS 345616-09-3C14H12FN3S
N-(5,6-Dimethylthieno[2,3-d]pyrimidin-4-yl)-N-(3-methoxyphenyl)amine chemical structure, C15H15N3OS, CAS 403734-37-2
N-(5,6-Dimethylthieno[2,3-d]pyrimidin-4-yl)-N-(3-methoxyphenyl)amine
CAS 403734-37-2C15H15N3OS
N-(3-Chlorophenyl)-6-methylthieno[2,3-d]pyrimidin-4-amine chemical structure, C13H10ClN3S, CAS 452087-18-2
N-(3-Chlorophenyl)-6-methylthieno[2,3-d]pyrimidin-4-amine
CAS 452087-18-2C13H10ClN3S
N-(4-Chlorophenyl)-6-ethylthieno[2,3-d]pyrimidin-4-amine chemical structure, C14H12ClN3S, CAS 423732-85-8
N-(4-Chlorophenyl)-6-ethylthieno[2,3-d]pyrimidin-4-amine
CAS 423732-85-8C14H12ClN3S
N-(3-Fluorophenyl)-5,6-dimethylthieno[2,3-d]pyrimidin-4-amine chemical structure, C14H12FN3S, CAS 797813-95-7
N-(3-Fluorophenyl)-5,6-dimethylthieno[2,3-d]pyrimidin-4-amine
CAS 797813-95-7C14H12FN3S
Methyl 4-[(5,6-dimethylthieno[2,3-d]pyrimidin-4-yl)amino]benzoate chemical structure, C16H15N3O2S, CAS 499134-08-6
Methyl 4-[(5,6-dimethylthieno[2,3-d]pyrimidin-4-yl)amino]benzoate
CAS 499134-08-6C16H15N3O2S
N-(4-((5,6-Dimethylthieno[2,3-d]pyrimidin-4-yl)amino)phenyl)acetamide chemical structure, C16H16N4OS, CAS 797813-96-8
N-(4-((5,6-Dimethylthieno[2,3-d]pyrimidin-4-yl)amino)phenyl)acetamide
CAS 797813-96-8C16H16N4OS
N-(3,4-Dimethylphenyl)-5,6-dimethylthieno[2,3-d]pyrimidin-4-amine chemical structure, C16H17N3S, CAS 292855-45-9
N-(3,4-Dimethylphenyl)-5,6-dimethylthieno[2,3-d]pyrimidin-4-amine
CAS 292855-45-9C16H17N3S
5,6-Dimethyl-N-phenylthieno[2,3-d]pyrimidin-4-amine chemical structure, C14H13N3S, CAS 314054-91-6
5,6-Dimethyl-N-phenylthieno[2,3-d]pyrimidin-4-amine
CAS 314054-91-6C14H13N3S
6-Ethyl-N-phenylthieno[2,3-d]pyrimidin-4-amine chemical structure, C14H13N3S, CAS 423733-48-6
6-Ethyl-N-phenylthieno[2,3-d]pyrimidin-4-amine
CAS 423733-48-6C14H13N3S
N-(2-Chlorophenyl)-6-ethylthieno[2,3-d]pyrimidin-4-amine chemical structure, C14H12ClN3S, CAS 5935-13-7
N-(2-Chlorophenyl)-6-ethylthieno[2,3-d]pyrimidin-4-amine
CAS 5935-13-7C14H12ClN3S
6-Ethyl-N-(4-methylphenyl)thieno[2,3-d]pyrimidin-4-amine chemical structure, C15H15N3S, CAS 423736-67-8
6-Ethyl-N-(4-methylphenyl)thieno[2,3-d]pyrimidin-4-amine
CAS 423736-67-8C15H15N3S
N-(4-Bromophenyl)-6-ethylthieno[2,3-d]pyrimidin-4-amine chemical structure, C14H12BrN3S, CAS 81136-43-8
N-(4-Bromophenyl)-6-ethylthieno[2,3-d]pyrimidin-4-amine
CAS 81136-43-8C14H12BrN3S
N-[4-Chloro-3-(trifluoromethyl)phenyl]-5,6-dimethylthieno[2,3-d]pyrimidin-4-amine chemical structure, C15H11ClF3N3S, CAS 345615-60-3
N-[4-Chloro-3-(trifluoromethyl)phenyl]-5,6-dimethylthieno[2,3-d]pyrimidin-4-amine
CAS 345615-60-3C15H11ClF3N3S
N-(3-Bromophenyl)thieno[2,3-d]pyrimidin-4-amine chemical structure, C12H8BrN3S, CAS 171179-15-0
N-(3-Bromophenyl)thieno[2,3-d]pyrimidin-4-amine
CAS 171179-15-0C12H8BrN3S
N-(5-Chloro-2-methoxyphenyl)thieno[2,3-d]pyrimidin-4-amine chemical structure, C13H10ClN3OS, CAS 726161-06-4
N-(5-Chloro-2-methoxyphenyl)thieno[2,3-d]pyrimidin-4-amine
CAS 726161-06-4C13H10ClN3OS
N-(3-Chloro-4-fluorophenyl)thieno[2,3-d]pyrimidin-4-amine chemical structure, C12H7ClFN3S, CAS 730994-22-6
N-(3-Chloro-4-fluorophenyl)thieno[2,3-d]pyrimidin-4-amine
CAS 730994-22-6C12H7ClFN3S