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Murcko scaffold

Ring system with 3 rings and 21 atoms

8 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
21
Chemicals
8
With full pages
4
Scaffold SMILES

O=C(CC(c1ccccc1)c1ccccc1)N1CCCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CC(c1ccccc1)c1ccccc1)N1CCCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 8 of 8 chemicals

3-(5-Bromo-2-hydroxyphenyl)-3-phenyl-1-pyrrolidin-1-ylpropan-1-one chemical structure, C19H20BrNO2, CAS 516470-72-7
3-(5-Bromo-2-hydroxyphenyl)-3-phenyl-1-pyrrolidin-1-ylpropan-1-one
CAS 516470-72-7C19H20BrNO2
3-Phenyl-3-(4-propan-2-yloxyphenyl)-1-pyrrolidin-1-ylpropan-1-one chemical structure, C22H27NO2, CAS 672284-17-2
3-Phenyl-3-(4-propan-2-yloxyphenyl)-1-pyrrolidin-1-ylpropan-1-one
CAS 672284-17-2C22H27NO2
3-(4-Fluorophenyl)-3-(4-methoxyphenyl)-1-pyrrolidin-1-ylpropan-1-one chemical structure, C20H22FNO2, CAS 849017-52-3
3-(4-Fluorophenyl)-3-(4-methoxyphenyl)-1-pyrrolidin-1-ylpropan-1-one
CAS 849017-52-3C20H22FNO2
3-(2-Hydroxy-5-methylphenyl)-3-phenyl-1-pyrrolidin-1-ylpropan-1-one chemical structure, C20H23NO2, CAS 516470-71-6
3-(2-Hydroxy-5-methylphenyl)-3-phenyl-1-pyrrolidin-1-ylpropan-1-one
CAS 516470-71-6C20H23NO2
Denagliptin chemical structure, C20H18F3N3O, CAS 483369-58-0
Denagliptin
CAS 483369-58-0C20H18F3N3O
Denagliptin tosylate chemical structure, C27H26F3N3O4S, CAS 811432-66-3
Denagliptin tosylate
CAS 811432-66-3C27H26F3N3O4S
tert-Butyl ((1S)-1-[bis(4-fluorophenyl)methyl]-2-[(2S,4S)-2-cyano-4-fluoro-1-pyrrolidinyl]-2-oxoethyl)carbamate chemical structure, C25H26F3N3O3, CAS 483368-24-7
tert-Butyl ((1S)-1-[bis(4-fluorophenyl)methyl]-2-[(2S,4S)-2-cyano-4-fluoro-1-pyrrolidinyl]-2-oxoethyl)carbamate
CAS 483368-24-7C25H26F3N3O3
1-(3-(tert-Butylsulfonyl)pyrrolidin-1-yl)-3,3-diphenylpropan-1-one chemical structure, C23H29NO3S, CAS 1448074-96-1
1-(3-(tert-Butylsulfonyl)pyrrolidin-1-yl)-3,3-diphenylpropan-1-one
CAS 1448074-96-1C23H29NO3S