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Murcko scaffold

Ring system with 4 rings and 26 atoms

6 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
26
Chemicals
6
With full pages
1
Scaffold SMILES

O=C(NCCc1ccccc1)c1cc(-c2cccs2)nc2ccccc12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NCCc1ccccc1)c1cc(-c2cccs2)nc2ccccc12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 6 of 6 chemicals

2-(5-Methylthiophen-2-yl)-N-(2-phenylethyl)quinoline-4-carboxamide chemical structure, C23H20N2OS, CAS 540758-21-2
2-(5-Methylthiophen-2-yl)-N-(2-phenylethyl)quinoline-4-carboxamide
CAS 540758-21-2C23H20N2OS
2-(5-Chlorothiophen-2-yl)-N-[2-(4-methoxyphenyl)ethyl]quinoline-4-carboxamide chemical structure, C23H19ClN2O2S, CAS 419559-23-2
2-(5-Chlorothiophen-2-yl)-N-[2-(4-methoxyphenyl)ethyl]quinoline-4-carboxamide
CAS 419559-23-2C23H19ClN2O2S
ROS kinases-IN-2 chemical structure, C22H19N3O3S2, CAS 687576-28-9
ROS kinases-IN-2
CAS 687576-28-9C22H19N3O3S2
N~4~-(3,4-dimethoxyphenethyl)-2-(2-thienyl)-4-quinolinecarboxamide chemical structure, C24H22N2O3S, CAS 544692-13-9
N~4~-(3,4-dimethoxyphenethyl)-2-(2-thienyl)-4-quinolinecarboxamide
CAS 544692-13-9C24H22N2O3S
N-[2-(3,4-Dimethoxyphenyl)ethyl]-2-(5-methylthiophen-2-yl)quinoline-4-carboxamide chemical structure, C25H24N2O3S, CAS 420093-15-8
N-[2-(3,4-Dimethoxyphenyl)ethyl]-2-(5-methylthiophen-2-yl)quinoline-4-carboxamide
CAS 420093-15-8C25H24N2O3S
2-(5-Bromothiophen-2-yl)-N-[2-(4-sulfamoylphenyl)ethyl]quinoline-4-carboxamide chemical structure, C22H18BrN3O3S2, CAS 892256-19-8
2-(5-Bromothiophen-2-yl)-N-[2-(4-sulfamoylphenyl)ethyl]quinoline-4-carboxamide
CAS 892256-19-8C22H18BrN3O3S2