Murcko scaffold
Ring system with 5 rings and 32 atoms
27 chemicals on CompoundList share this ring system.
- Rings
- 5
- Scaffold atoms
- 32
- Chemicals
- 27
- With full pages
- 4
Scaffold SMILES
O=C(c1ccc(OCCN2CCCCC2)cc1)c1c(-c2ccccc2)sc2ccccc12
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 27 of 27 chemicals
Raloxifene
CAS 84449-90-1C28H27NO4S
Raloxifene hydrochloride
CAS 82640-04-8C28H28ClNO4S
Diacetylcymarol
CAS 6473-40-1C29H30N2O5S2
Raloxifene-4'-ethyl ether
CAS 1026927-78-5C30H31NO4S
LY-329146
CAS 191043-78-4C30H32N2O7S3
![6-Methanesulfonyloxy-2-(4-methanesulfonyloxyphenyl)-3-[4-(2-piperidinoethoxy)-benzoyl]benzo[b]thiophene chemical structure, C30H31NO8S3, CAS 84541-30-0](/s/USNAACYIFLJJST-UHFFFAOYSA-N.svg)
6-Methanesulfonyloxy-2-(4-methanesulfonyloxyphenyl)-3-[4-(2-piperidinoethoxy)-benzoyl]benzo[b]thiophene
CAS 84541-30-0C30H31NO8S3
Raloxifene 4-monomethyl ether
CAS 185415-07-0C29H29NO4S
4'-tert-Butyldimethylsilyl-6-hydroxy Raloxifene
CAS 174264-46-1C34H41NO4SSi
![(6-Methoxy-2-phenylbenzo[b]thien-3-yl)[4-[2-(1-piperidinyl)ethoxy]phenyl]methanone chemical structure, C29H29NO3S, CAS 185416-18-6](/s/GPKIORIMKNVYJP-UHFFFAOYSA-N.svg)
(6-Methoxy-2-phenylbenzo[b]thien-3-yl)[4-[2-(1-piperidinyl)ethoxy]phenyl]methanone
CAS 185416-18-6C29H29NO3S
Raloxifene 6-monomethyl ether
CAS 178451-13-3C29H29NO4S
6-tert-Butyldimethylsilyl-4'-hydroxy Raloxifene
CAS 174264-47-2C34H41NO4SSi
Raloxifene bismethyl ether
CAS 84541-38-8C30H31NO4S
4,6-Di(tert-butyldimethylsily) raloxifene
CAS 182249-24-7C40H55NO4SSi2
4-Hydroxy raloxifene
CAS 185416-01-7C28H27NO4S
![6-Acetoxy-2-(4-acetoxyphenyl)-3-[4-(2-piperidinoethoxy)benzoyl]benzo[b]thiophene chemical structure, C32H31NO6S, CAS 84541-33-3](/s/PDTVFZPKYBBZIC-UHFFFAOYSA-N.svg)
6-Acetoxy-2-(4-acetoxyphenyl)-3-[4-(2-piperidinoethoxy)benzoyl]benzo[b]thiophene
CAS 84541-33-3C32H31NO6S
Raloxifene N-oxide
CAS 195454-31-0C28H27NO5S
(6-((Methylsulfonyl)oxy)-2-(4-((methylsulfonyl)oxy)phenyl)benzo(b)thien-3-yl)(4-(2-(1-piperidinyl)ethoxy)phenyl)-, hydrochloride
CAS 84449-85-4C30H32ClNO8S3
Raloxifene hydrochloride hydrate
CAS 1020061-04-4C28H30ClNO5S
Raloxifene-d10 (piperidine-d10)
CAS 2512224-37-0C28H27NO4S
Raloxifene-d4
CAS 1185076-44-1C28H27NO4S
6-Hydroxy-4'-tert-butyldimethylsylyl Raloxifene-d4
CAS 1189422-34-1C34H41NO4SSi
Raloxifene-d4 bismethyl ether
CAS 1185006-58-9C30H31NO4S
Raloxifene Bismethyl Ether (hydrochloride)
CAS 84541-36-6C30H32ClNO4S
Raloxifene-d4 hydrochloride
CAS 1188263-47-9C28H28ClNO4S
Related scaffolds
Same ring framework with different atoms or bond orders
