Murcko scaffold
Ring system with 4 rings and 27 atoms
29 chemicals on CompoundList share this ring system.
- Rings
- 4
- Scaffold atoms
- 27
- Chemicals
- 29
- With full pages
- 7
Scaffold SMILES
O=C(c1ccncc1)N(c1ccc2occc2c1)S(=O)(=O)c1ccccc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 29 of 29 chemicals
amino]-2-methyl-1-benzofuran-3-carboxylate chemical structure, C26H24N2O6S, CAS 518320-21-3](/s/AYEGBPVXJZSKQP-UHFFFAOYSA-N.svg)
Ethyl 5-[[(2,5-dimethylphenyl)sulfonyl](isonicotinoyl)amino]-2-methyl-1-benzofuran-3-carboxylate
CAS 518320-21-3C26H24N2O6S
amino]-2-methyl-1-benzofuran-3-carboxylate chemical structure, C25H22N2O6S, CAS 518321-19-2](/s/QHVUMCPJZWNQIC-UHFFFAOYSA-N.svg)
Methyl 5-[[(2,4-dimethylphenyl)sulfonyl](isonicotinoyl)amino]-2-methyl-1-benzofuran-3-carboxylate
CAS 518321-19-2C25H22N2O6S
amino]-2-methyl-1-benzofuran-3-carboxylate chemical structure, C26H24N2O6S, CAS 518321-20-5](/s/VVVFCKKEEWIOIX-UHFFFAOYSA-N.svg)
Ethyl 5-[[(2,4-dimethylphenyl)sulfonyl](isonicotinoyl)amino]-2-methyl-1-benzofuran-3-carboxylate
CAS 518321-20-5C26H24N2O6S
N-(3-Acetyl-2-methyl-1-benzofuran-5-yl)-N-isonicotinoyl-2,4,5-trimethylbenzenesulfonamide
CAS 518319-89-6C26H24N2O5S
![Methyl 5-[(4-methoxyphenyl)sulfonyl-(pyridine-4-carbonyl)amino]-2-methyl-1-benzofuran-3-carboxylate chemical structure, C24H20N2O7S, CAS 518318-57-5](/s/UYGLWCPGTLHAEQ-UHFFFAOYSA-N.svg)
Methyl 5-[(4-methoxyphenyl)sulfonyl-(pyridine-4-carbonyl)amino]-2-methyl-1-benzofuran-3-carboxylate
CAS 518318-57-5C24H20N2O7S
![Ethyl 5-{isonicotinoyl[(4-methoxyphenyl)sulfonyl]amino}-2-methyl-1-benzofuran-3-carboxylate chemical structure, C25H22N2O7S, CAS 518318-64-4](/s/XNTXGFLZRUCIHA-UHFFFAOYSA-N.svg)
Ethyl 5-{isonicotinoyl[(4-methoxyphenyl)sulfonyl]amino}-2-methyl-1-benzofuran-3-carboxylate
CAS 518318-64-4C25H22N2O7S
amino]-2-methyl-1-benzofuran-3-carboxylate chemical structure, C24H19FN2O6S, CAS 518319-16-9](/s/XDAAGHOAHCHAHM-UHFFFAOYSA-N.svg)
Ethyl 5-[[(4-fluorophenyl)sulfonyl](isonicotinoyl)amino]-2-methyl-1-benzofuran-3-carboxylate
CAS 518319-16-9C24H19FN2O6S
amino]-2-methyl-1-benzofuran-3-carboxylate chemical structure, C25H22N2O7S, CAS 518318-11-1](/s/COIRMOGEVCRKJO-UHFFFAOYSA-N.svg)
Methyl 5-[[(4-ethoxyphenyl)sulfonyl](isonicotinoyl)amino]-2-methyl-1-benzofuran-3-carboxylate
CAS 518318-11-1C25H22N2O7S
N-(3-Acetyl-2-methyl-1-benzofuran-5-yl)-N-isonicotinoyl-2,4,6-trimethylbenzenesulfonamide
CAS 518317-49-2C26H24N2O5S
![Methyl 5-[isonicotinoyl(mesitylsulfonyl)amino]-2-methyl-1-benzofuran-3-carboxylate chemical structure, C26H24N2O6S, CAS 518317-51-6](/s/OMPJKZXTRDFZEM-UHFFFAOYSA-N.svg)
Methyl 5-[isonicotinoyl(mesitylsulfonyl)amino]-2-methyl-1-benzofuran-3-carboxylate
CAS 518317-51-6C26H24N2O6S
amino}-2-methyl-1-benzofuran-3-carboxylate chemical structure, C24H19FN2O6S, CAS 692761-93-6](/s/NUXCQJMYWRNZJU-UHFFFAOYSA-N.svg)
Methyl 5-{[(4-fluoro-2-methylphenyl)sulfonyl](pyridin-4-ylcarbonyl)amino}-2-methyl-1-benzofuran-3-carboxylate
CAS 692761-93-6C24H19FN2O6S
N-(3-Acetyl-2-methyl-1-benzofuran-5-yl)-N-isonicotinoyl-4-methylbenzenesulfonamide
CAS 305374-66-7C24H20N2O5S
N-(3-Acetyl-2-methyl-1-benzofuran-5-yl)-4-tert-butyl-N-isonicotinoylbenzenesulfonamide
CAS 305374-67-8C27H26N2O5S
![Ethyl 5-{isonicotinoyl[(4-methylphenyl)sulfonyl]amino}-2-methyl-1-benzofuran-3-carboxylate chemical structure, C25H22N2O6S, CAS 305374-69-0](/s/HCNQOKKSHPOWCO-UHFFFAOYSA-N.svg)
Ethyl 5-{isonicotinoyl[(4-methylphenyl)sulfonyl]amino}-2-methyl-1-benzofuran-3-carboxylate
CAS 305374-69-0C25H22N2O6S
N-(3-Acetyl-2-methyl-1-benzofuran-5-yl)-N-isonicotinoyl-2,5-dimethylbenzenesulfonamide
CAS 518320-34-8C25H22N2O5S
N-(3-Acetyl-2-methyl-1-benzofuran-5-yl)-N-isonicotinoyl-4-methoxybenzenesulfonamide
CAS 518318-56-4C24H20N2O6S
Ethyl 2-methyl-5-(N-(phenylsulfonyl)isonicotinamido)benzofuran-3-carboxylate
CAS 406475-59-0C24H20N2O6S
![Methyl 5-[isonicotinoyl(phenylsulfonyl)amino]-2-methyl-1-benzofuran-3-carboxylate chemical structure, C23H18N2O6S, CAS 313393-99-6](/s/DKISKQNHOKXADD-UHFFFAOYSA-N.svg)
Methyl 5-[isonicotinoyl(phenylsulfonyl)amino]-2-methyl-1-benzofuran-3-carboxylate
CAS 313393-99-6C23H18N2O6S
N-(3-Acetyl-2-methyl-1-benzofuran-5-yl)-4-ethyl-N-isonicotinoylbenzenesulfonamide
CAS 397281-35-5C25H22N2O5S
N-(3-Acetyl-2-methyl-1-benzofuran-5-yl)-N-(4-chlorophenyl)sulfonylpyridine-4-carboxamide
CAS 448208-40-0C23H17ClN2O5S
N-(3-Acetyl-2-methyl-1-benzofuran-5-yl)-N-(4-fluoro-2-methylphenyl)sulfonylpyridine-4-carboxamide
CAS 708236-51-5C24H19FN2O5S
amino]-2-methyl-1-benzofuran-3-carboxylate chemical structure, C25H21FN2O6S, CAS 708240-11-3](/s/NJKYLWKLSSVJIZ-UHFFFAOYSA-N.svg)
Ethyl 5-[[(4-fluoro-2-methylphenyl)sulfonyl](isonicotinoyl)amino]-2-methyl-1-benzofuran-3-carboxylate
CAS 708240-11-3C25H21FN2O6S
Ethyl 5-(N-((4-chlorophenyl)sulfonyl)isonicotinamido)-2-methylbenzofuran-3-carboxylate
CAS 420107-33-1C24H19ClN2O6S
N-(3-Acetyl-2-methyl-1-benzofuran-5-yl)-N-(4-fluorophenyl)sulfonylpyridine-4-carboxamide
CAS 518319-18-1C23H17FN2O5S
- Ethyl 5-{[(4-ethoxyphenyl)sulfonyl](pyridin-4-ylcarbonyl)amino}-2-methyl-1-benzofuran-3-carboxylate518318-04-2C26H24N2O7S
- Methyl 5-[N-(4-tert-butylbenzenesulfonyl)pyridine-4-amido]-2-methyl-1-benzofuran-3-carboxylate448213-95-4C27H26N2O6S
- Methyl 5-[[(4-chlorophenyl)sulfonyl](isonicotinoyl)amino]-2-methyl-1-benzofuran-3-carboxylate380886-11-3C23H17ClN2O6S
- Methyl 2-methyl-5-(N-((3-nitrophenyl)sulfonyl)isonicotinamido)benzofuran-3-carboxylate448213-33-0C23H17N3O8S
- Ethyl 2-methyl-5-(N-((3-nitrophenyl)sulfonyl)isonicotinamido)benzofuran-3-carboxylate448209-92-5C24H19N3O8S