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Murcko scaffold

Ring system with 4 rings and 30 atoms

22 chemicals on CompoundList share this ring system.

Rings: 4
Scaffold atoms: 30
Chemicals: 22
With full pages: 4

Scaffold SMILES

O=C(CSc1oc(-c2ccco2)nc1S(=O)(=O)c1ccccc1)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold

Murcko scaffold O=C(CSc1oc(-c2ccco2)nc1S(=O)(=O)c1ccccc1)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 22 of 22 chemicals

2-{[4-(Benzenesulfonyl)-2-(furan-2-yl)-1,3-oxazol-5-yl]sulfanyl}-N-(4-fluorophenyl)acetamide chemical structure, C21H15FN2O5S2, CAS 686737-43-9

2-{[4-(Benzenesulfonyl)-2-(furan-2-yl)-1,3-oxazol-5-yl]sulfanyl}-N-(4-fluorophenyl)acetamide

CAS 686737-43-9C₂₁H₁₅FN₂O₅S₂

N-(3,5-Dimethylphenyl)-2-({2-(furan-2-yl)-4-[(4-methylphenyl)sulfonyl]-1,3-oxazol-5-yl}sulfanyl)acetamide chemical structure, C24H22N2O5S2, CAS 686737-60-0

N-(3,5-Dimethylphenyl)-2-({2-(furan-2-yl)-4-[(4-methylphenyl)sulfonyl]-1,3-oxazol-5-yl}sulfanyl)acetamide

CAS 686737-60-0C₂₄H₂₂N₂O₅S₂

N-(3,5-Dimethylphenyl)-2-[[4-(4-fluorophenyl)sulfonyl-2-(furan-2-yl)-1,3-oxazol-5-yl]sulfanyl]acetamide chemical structure, C23H19FN2O5S2, CAS 850928-57-3

N-(3,5-Dimethylphenyl)-2-[[4-(4-fluorophenyl)sulfonyl-2-(furan-2-yl)-1,3-oxazol-5-yl]sulfanyl]acetamide

CAS 850928-57-3C₂₃H₁₉FN₂O₅S₂

2-{[4-(Benzenesulfonyl)-2-(furan-2-yl)-1,3-oxazol-5-yl]sulfanyl}-N-(4-ethoxyphenyl)acetamide chemical structure, C23H20N2O6S2, CAS 686737-44-0

2-{[4-(Benzenesulfonyl)-2-(furan-2-yl)-1,3-oxazol-5-yl]sulfanyl}-N-(4-ethoxyphenyl)acetamide

CAS 686737-44-0C₂₃H₂₀N₂O₆S₂

2-[[4-(Benzenesulfonyl)-2-(furan-2-yl)-1,3-oxazol-5-yl]sulfanyl]-N-(3,5-dimethylphenyl)acetamide chemical structure, C23H20N2O5S2, CAS 686737-45-1

2-[[4-(Benzenesulfonyl)-2-(furan-2-yl)-1,3-oxazol-5-yl]sulfanyl]-N-(3,5-dimethylphenyl)acetamide

CAS 686737-45-1C₂₃H₂₀N₂O₅S₂

2-{[4-(Benzenesulfonyl)-2-(furan-2-yl)-1,3-oxazol-5-yl]sulfanyl}-N-(2,4-dimethoxyphenyl)acetamide chemical structure, C23H20N2O7S2, CAS 686737-46-2

2-{[4-(Benzenesulfonyl)-2-(furan-2-yl)-1,3-oxazol-5-yl]sulfanyl}-N-(2,4-dimethoxyphenyl)acetamide

CAS 686737-46-2C₂₃H₂₀N₂O₇S₂

2-{[2-(Furan-2-yl)-4-(phenylsulfonyl)-1,3-oxazol-5-yl]sulfanyl}-N-(2-methoxyphenyl)acetamide chemical structure, C22H18N2O6S2, CAS 686737-50-8

2-{[2-(Furan-2-yl)-4-(phenylsulfonyl)-1,3-oxazol-5-yl]sulfanyl}-N-(2-methoxyphenyl)acetamide

CAS 686737-50-8C₂₂H₁₈N₂O₆S₂

N-(4-Fluorophenyl)-2-{[2-(furan-2-yl)-4-(4-methylbenzenesulfonyl)-1,3-oxazol-5-yl]sulfanyl}acetamide chemical structure, C22H17FN2O5S2, CAS 686737-58-6

N-(4-Fluorophenyl)-2-{[2-(furan-2-yl)-4-(4-methylbenzenesulfonyl)-1,3-oxazol-5-yl]sulfanyl}acetamide

CAS 686737-58-6C₂₂H₁₇FN₂O₅S₂

N-(4-Ethoxyphenyl)-2-{[2-(furan-2-yl)-4-(4-methylbenzenesulfonyl)-1,3-oxazol-5-yl]sulfanyl}acetamide chemical structure, C24H22N2O6S2, CAS 686737-59-7

N-(4-Ethoxyphenyl)-2-{[2-(furan-2-yl)-4-(4-methylbenzenesulfonyl)-1,3-oxazol-5-yl]sulfanyl}acetamide

CAS 686737-59-7C₂₄H₂₂N₂O₆S₂

N-(2,4-Dimethoxyphenyl)-2-[[2-(furan-2-yl)-4-(4-methylphenyl)sulfonyl-1,3-oxazol-5-yl]sulfanyl]acetamide chemical structure, C24H22N2O7S2, CAS 686737-61-1

N-(2,4-Dimethoxyphenyl)-2-[[2-(furan-2-yl)-4-(4-methylphenyl)sulfonyl-1,3-oxazol-5-yl]sulfanyl]acetamide

CAS 686737-61-1C₂₄H₂₂N₂O₇S₂

2-({2-(Furan-2-yl)-4-[(4-methylphenyl)sulfonyl]-1,3-oxazol-5-yl}sulfanyl)-N-(2-methoxyphenyl)acetamide chemical structure, C23H20N2O6S2, CAS 686737-65-5

2-({2-(Furan-2-yl)-4-[(4-methylphenyl)sulfonyl]-1,3-oxazol-5-yl}sulfanyl)-N-(2-methoxyphenyl)acetamide

CAS 686737-65-5C₂₃H₂₀N₂O₆S₂

2-((4-((4-Chlorophenyl)sulfonyl)-2-(furan-2-yl)oxazol-5-yl)thio)-N-(4-fluorophenyl)acetamide chemical structure, C21H14ClFN2O5S2, CAS 686737-82-6

2-((4-((4-Chlorophenyl)sulfonyl)-2-(furan-2-yl)oxazol-5-yl)thio)-N-(4-fluorophenyl)acetamide

CAS 686737-82-6C₂₁H₁₄ClFN₂O₅S₂

2-[[4-(4-Chlorophenyl)sulfonyl-2-(furan-2-yl)-1,3-oxazol-5-yl]sulfanyl]-N-(4-ethoxyphenyl)acetamide chemical structure, C23H19ClN2O6S2, CAS 686737-84-8

2-[[4-(4-Chlorophenyl)sulfonyl-2-(furan-2-yl)-1,3-oxazol-5-yl]sulfanyl]-N-(4-ethoxyphenyl)acetamide

CAS 686737-84-8C₂₃H₁₉ClN₂O₆S₂

2-[[4-(4-Chlorophenyl)sulfonyl-2-(furan-2-yl)-1,3-oxazol-5-yl]sulfanyl]-N-(2,4-dimethoxyphenyl)acetamide chemical structure, C23H19ClN2O7S2, CAS 686737-87-1

2-[[4-(4-Chlorophenyl)sulfonyl-2-(furan-2-yl)-1,3-oxazol-5-yl]sulfanyl]-N-(2,4-dimethoxyphenyl)acetamide

CAS 686737-87-1C₂₃H₁₉ClN₂O₇S₂

2-[[4-(4-Chlorophenyl)sulfonyl-2-(furan-2-yl)-1,3-oxazol-5-yl]sulfanyl]-N-(2-methoxyphenyl)acetamide chemical structure, C22H17ClN2O6S2, CAS 686737-95-1

2-[[4-(4-Chlorophenyl)sulfonyl-2-(furan-2-yl)-1,3-oxazol-5-yl]sulfanyl]-N-(2-methoxyphenyl)acetamide

CAS 686737-95-1C₂₂H₁₇ClN₂O₆S₂

2-((4-((4-Bromophenyl)sulfonyl)-2-(furan-2-yl)oxazol-5-yl)thio)-N-(4-fluorophenyl)acetamide chemical structure, C21H14BrFN2O5S2, CAS 686738-19-2

2-((4-((4-Bromophenyl)sulfonyl)-2-(furan-2-yl)oxazol-5-yl)thio)-N-(4-fluorophenyl)acetamide

CAS 686738-19-2C₂₁H₁₄BrFN₂O₅S₂

2-[[4-(4-Bromophenyl)sulfonyl-2-(furan-2-yl)-1,3-oxazol-5-yl]sulfanyl]-N-(4-ethoxyphenyl)acetamide chemical structure, C23H19BrN2O6S2, CAS 686738-20-5

2-[[4-(4-Bromophenyl)sulfonyl-2-(furan-2-yl)-1,3-oxazol-5-yl]sulfanyl]-N-(4-ethoxyphenyl)acetamide

CAS 686738-20-5C₂₃H₁₉BrN₂O₆S₂

2-[[4-(4-Bromophenyl)sulfonyl-2-(furan-2-yl)-1,3-oxazol-5-yl]sulfanyl]-N-(3,5-dimethylphenyl)acetamide chemical structure, C23H19BrN2O5S2, CAS 686738-22-7

2-[[4-(4-Bromophenyl)sulfonyl-2-(furan-2-yl)-1,3-oxazol-5-yl]sulfanyl]-N-(3,5-dimethylphenyl)acetamide

CAS 686738-22-7C₂₃H₁₉BrN₂O₅S₂

2-{[4-(4-Bromobenzenesulfonyl)-2-(furan-2-yl)-1,3-oxazol-5-yl]sulfanyl}-N-(2,4-dimethoxyphenyl)acetamide chemical structure, C23H19BrN2O7S2, CAS 686738-24-9

2-{[4-(4-Bromobenzenesulfonyl)-2-(furan-2-yl)-1,3-oxazol-5-yl]sulfanyl}-N-(2,4-dimethoxyphenyl)acetamide

CAS 686738-24-9C₂₃H₁₉BrN₂O₇S₂

2-((4-((4-Bromophenyl)sulfonyl)-2-(furan-2-yl)oxazol-5-yl)thio)-N-(2-methoxyphenyl)acetamide chemical structure, C22H17BrN2O6S2, CAS 686738-28-3

2-((4-((4-Bromophenyl)sulfonyl)-2-(furan-2-yl)oxazol-5-yl)thio)-N-(2-methoxyphenyl)acetamide

CAS 686738-28-3C₂₂H₁₇BrN₂O₆S₂

N-(4-Fluorophenyl)-2-((4-((4-fluorophenyl)sulfonyl)-2-(furan-2-yl)oxazol-5-yl)thio)acetamide sulfate chemical structure, C21H16F2N2O9S3, CAS 1329960-62-4

N-(4-Fluorophenyl)-2-((4-((4-fluorophenyl)sulfonyl)-2-(furan-2-yl)oxazol-5-yl)thio)acetamide sulfate

CAS 1329960-62-4C₂₁H₁₆F₂N₂O₉S₃

2-((4-((4-Fluorophenyl)sulfonyl)-2-(furan-2-yl)oxazol-5-yl)thio)-N-(2-methoxyphenyl)acetamide sulfate chemical structure, C22H19FN2O10S3, CAS 1330369-30-6

2-((4-((4-Fluorophenyl)sulfonyl)-2-(furan-2-yl)oxazol-5-yl)thio)-N-(2-methoxyphenyl)acetamide sulfate

CAS 1330369-30-6C₂₂H₁₉FN₂O₁₀S₃