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Murcko scaffold

N-Benzyl-2-[(2-oxo-1,5,6,7-tetrahydrocyclopenta[d]pyrimidin-4-yl)sulfanyl]acetamide scaffold

14 chemicals on CompoundList share this ring system.

Rings: 3
Scaffold atoms: 22
Chemicals: 14
With full pages: 2

Scaffold SMILES

O=C(CSc1nc(=O)[nH]c2c1CCC2)NCc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold Open the N-Benzyl-2-[(2-oxo-1,5,6,7-tetrahydrocyclopenta[d]pyrimidin-4-yl)sulfanyl]acetamide page

Murcko scaffold O=C(CSc1nc(=O)[nH]c2c1CCC2)NCc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 14 of 14 chemicals

N-[(4-Methylphenyl)methyl]-2-[(2-oxo-1,5,6,7-tetrahydrocyclopenta[d]pyrimidin-4-yl)sulfanyl]acetamide chemical structure, C17H19N3O2S, CAS 946269-16-5

N-[(4-Methylphenyl)methyl]-2-[(2-oxo-1,5,6,7-tetrahydrocyclopenta[d]pyrimidin-4-yl)sulfanyl]acetamide

CAS 946269-16-5C₁₇H₁₉N₃O₂S

N-[(4-Chlorophenyl)methyl]-2-[(2-oxo-1,5,6,7-tetrahydrocyclopenta[d]pyrimidin-4-yl)sulfanyl]acetamide chemical structure, C16H16ClN3O2S, CAS 959568-04-8

N-[(4-Chlorophenyl)methyl]-2-[(2-oxo-1,5,6,7-tetrahydrocyclopenta[d]pyrimidin-4-yl)sulfanyl]acetamide

CAS 959568-04-8C₁₆H₁₆ClN₃O₂S

N-Benzyl-2-[(2-oxo-1,5,6,7-tetrahydrocyclopenta[d]pyrimidin-4-yl)sulfanyl]acetamide chemical structure, C16H17N3O2S, CAS 933230-32-1

N-Benzyl-2-[(2-oxo-1,5,6,7-tetrahydrocyclopenta[d]pyrimidin-4-yl)sulfanyl]acetamide

CAS 933230-32-1C₁₆H₁₇N₃O₂S

N-[(4-Fluorophenyl)methyl]-2-[(2-oxo-1,5,6,7-tetrahydrocyclopenta[d]pyrimidin-4-yl)sulfanyl]acetamide chemical structure, C16H16FN3O2S, CAS 959492-32-1

N-[(4-Fluorophenyl)methyl]-2-[(2-oxo-1,5,6,7-tetrahydrocyclopenta[d]pyrimidin-4-yl)sulfanyl]acetamide

CAS 959492-32-1C₁₆H₁₆FN₃O₂S

N-Benzyl-2-((1-(2-(dimethylamino)ethyl)-2-oxo-2,5,6,7-tetrahydro-1H-cyclopenta[d]pyrimidin-4-yl)thio)acetamide chemical structure, C20H26N4O2S, CAS 898445-37-9

N-Benzyl-2-((1-(2-(dimethylamino)ethyl)-2-oxo-2,5,6,7-tetrahydro-1H-cyclopenta[d]pyrimidin-4-yl)thio)acetamide

CAS 898445-37-9C₂₀H₂₆N₄O₂S

N-Benzyl-2-((1-(2-(diethylamino)ethyl)-2-oxo-2,5,6,7-tetrahydro-1H-cyclopenta[d]pyrimidin-4-yl)thio)acetamide chemical structure, C22H30N4O2S, CAS 898459-60-4

N-Benzyl-2-((1-(2-(diethylamino)ethyl)-2-oxo-2,5,6,7-tetrahydro-1H-cyclopenta[d]pyrimidin-4-yl)thio)acetamide

CAS 898459-60-4C₂₂H₃₀N₄O₂S

N-Benzyl-2-((1-(2-hydroxyethyl)-2-oxo-2,5,6,7-tetrahydro-1H-cyclopenta[d]pyrimidin-4-yl)thio)acetamide chemical structure, C18H21N3O3S, CAS 941887-89-4

N-Benzyl-2-((1-(2-hydroxyethyl)-2-oxo-2,5,6,7-tetrahydro-1H-cyclopenta[d]pyrimidin-4-yl)thio)acetamide

CAS 941887-89-4C₁₈H₂₁N₃O₃S

N-(4-Fluorobenzyl)-2-((1-(2-hydroxyethyl)-2-oxo-2,5,6,7-tetrahydro-1H-cyclopenta[d]pyrimidin-4-yl)thio)acetamide chemical structure, C18H20FN3O3S, CAS 899742-86-0

N-(4-Fluorobenzyl)-2-((1-(2-hydroxyethyl)-2-oxo-2,5,6,7-tetrahydro-1H-cyclopenta[d]pyrimidin-4-yl)thio)acetamide

CAS 899742-86-0C₁₈H₂₀FN₃O₃S

2-((1-(2-Hydroxyethyl)-2-oxo-2,5,6,7-tetrahydro-1H-cyclopenta[d]pyrimidin-4-yl)thio)-N-(4-methylbenzyl)acetamide chemical structure, C19H23N3O3S, CAS 941920-16-7

2-((1-(2-Hydroxyethyl)-2-oxo-2,5,6,7-tetrahydro-1H-cyclopenta[d]pyrimidin-4-yl)thio)-N-(4-methylbenzyl)acetamide

CAS 941920-16-7C₁₉H₂₃N₃O₃S

2-((1-(2-Hydroxyethyl)-2-oxo-2,5,6,7-tetrahydro-1H-cyclopenta[d]pyrimidin-4-yl)thio)-N-(2-methoxybenzyl)acetamide chemical structure, C19H23N3O4S, CAS 899973-55-8

2-((1-(2-Hydroxyethyl)-2-oxo-2,5,6,7-tetrahydro-1H-cyclopenta[d]pyrimidin-4-yl)thio)-N-(2-methoxybenzyl)acetamide

CAS 899973-55-8C₁₉H₂₃N₃O₄S

N-(4-Chlorobenzyl)-2-((1-(2-hydroxyethyl)-2-oxo-2,5,6,7-tetrahydro-1H-cyclopenta[d]pyrimidin-4-yl)thio)acetamide chemical structure, C18H20ClN3O3S, CAS 920233-41-6

N-(4-Chlorobenzyl)-2-((1-(2-hydroxyethyl)-2-oxo-2,5,6,7-tetrahydro-1H-cyclopenta[d]pyrimidin-4-yl)thio)acetamide

CAS 920233-41-6C₁₈H₂₀ClN₃O₃S

N-(4-Fluorobenzyl)-2-((1-(3-hydroxypropyl)-2-oxo-2,5,6,7-tetrahydro-1H-cyclopenta[d]pyrimidin-4-yl)thio)acetamide chemical structure, C19H22FN3O3S, CAS 899973-82-1

N-(4-Fluorobenzyl)-2-((1-(3-hydroxypropyl)-2-oxo-2,5,6,7-tetrahydro-1H-cyclopenta[d]pyrimidin-4-yl)thio)acetamide

CAS 899973-82-1C₁₉H₂₂FN₃O₃S

2-((1-(3-Hydroxypropyl)-2-oxo-2,5,6,7-tetrahydro-1H-cyclopenta[d]pyrimidin-4-yl)thio)-N-(4-methylbenzyl)acetamide chemical structure, C20H25N3O3S, CAS 941888-22-8

2-((1-(3-Hydroxypropyl)-2-oxo-2,5,6,7-tetrahydro-1H-cyclopenta[d]pyrimidin-4-yl)thio)-N-(4-methylbenzyl)acetamide

CAS 941888-22-8C₂₀H₂₅N₃O₃S

N-(4-Chlorobenzyl)-2-((1-(3-hydroxypropyl)-2-oxo-2,5,6,7-tetrahydro-1H-cyclopenta[d]pyrimidin-4-yl)thio)acetamide chemical structure, C19H22ClN3O3S, CAS 920254-67-7

N-(4-Chlorobenzyl)-2-((1-(3-hydroxypropyl)-2-oxo-2,5,6,7-tetrahydro-1H-cyclopenta[d]pyrimidin-4-yl)thio)acetamide

CAS 920254-67-7C₁₉H₂₂ClN₃O₃S