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Murcko scaffold

6-Phenyl-6,7-dihydro[1,2,4]triazolo[5,1-b]quinazolin-8(5H)-one scaffold

33 chemicals on CompoundList share this ring system.

Rings: 4
Scaffold atoms: 20
Chemicals: 33
With full pages: 4

Scaffold SMILES

O=C1CC(c2ccccc2)Cc2nc3ncnn3cc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold Open the 6-Phenyl-6,7-dihydro[1,2,4]triazolo[5,1-b]quinazolin-8(5H)-one page

Murcko scaffold O=C1CC(c2ccccc2)Cc2nc3ncnn3cc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 33 of 33 chemicals

2-Methyl-6-phenyl-6,7-dihydro[1,2,4]triazolo[5,1-b]quinazolin-8(5H)-one chemical structure, C16H14N4O, CAS 777867-27-3

2-Methyl-6-phenyl-6,7-dihydro[1,2,4]triazolo[5,1-b]quinazolin-8(5H)-one

CAS 777867-27-3C₁₆H₁₄N₄O

6-Phenyl-6,7-dihydro[1,2,4]triazolo[5,1-b]quinazolin-8(5H)-one chemical structure, C15H12N4O, CAS 777867-26-2

6-Phenyl-6,7-dihydro[1,2,4]triazolo[5,1-b]quinazolin-8(5H)-one

CAS 777867-26-2C₁₅H₁₂N₄O

6-Phenyl-2-(trifluoromethyl)-6,7-dihydro[1,2,4]triazolo[5,1-b]quinazolin-8(5H)-one chemical structure, C16H11F3N4O, CAS 777867-28-4

6-Phenyl-2-(trifluoromethyl)-6,7-dihydro[1,2,4]triazolo[5,1-b]quinazolin-8(5H)-one

CAS 777867-28-4C₁₆H₁₁F₃N₄O

2-(Methylthio)-6-phenyl-6,7-dihydro-5H-[1,2,4]triazolo[5,1-b]quinazolin-8-one chemical structure, C16H14N4OS, CAS 777867-29-5

2-(Methylthio)-6-phenyl-6,7-dihydro-5H-[1,2,4]triazolo[5,1-b]quinazolin-8-one

CAS 777867-29-5C₁₆H₁₄N₄OS

Methyl [(8-oxo-6-phenyl-5,6,7,8-tetrahydro[1,2,4]triazolo[5,1-b]quinazolin-2-yl)thio]acetate chemical structure, C18H16N4O3S, CAS 777867-35-3

Methyl [(8-oxo-6-phenyl-5,6,7,8-tetrahydro[1,2,4]triazolo[5,1-b]quinazolin-2-yl)thio]acetate

CAS 777867-35-3C₁₈H₁₆N₄O₃S

6-(4-Methoxyphenyl)-2-(trifluoromethyl)-6,7-dihydro[1,2,4]triazolo[5,1-b]quinazolin-8(5H)-one chemical structure, C17H13F3N4O2, CAS 878995-01-8

6-(4-Methoxyphenyl)-2-(trifluoromethyl)-6,7-dihydro[1,2,4]triazolo[5,1-b]quinazolin-8(5H)-one

CAS 878995-01-8C₁₇H₁₃F₃N₄O₂

6-(3,4-Dimethoxyphenyl)-2-methyl-6,7-dihydro[1,2,4]triazolo[5,1-b]quinazolin-8(5H)-one chemical structure, C18H18N4O3, CAS 878995-02-9

6-(3,4-Dimethoxyphenyl)-2-methyl-6,7-dihydro[1,2,4]triazolo[5,1-b]quinazolin-8(5H)-one

CAS 878995-02-9C₁₈H₁₈N₄O₃

6-(4-Fluorophenyl)-2-(trifluoromethyl)-6,7-dihydro[1,2,4]triazolo[5,1-b]quinazolin-8(5H)-one chemical structure, C16H10F4N4O, CAS 879568-95-3

6-(4-Fluorophenyl)-2-(trifluoromethyl)-6,7-dihydro[1,2,4]triazolo[5,1-b]quinazolin-8(5H)-one

CAS 879568-95-3C₁₆H₁₀F₄N₄O

2-Ethyl-6-[4-(propan-2-yl)phenyl]-6,7-dihydro[1,2,4]triazolo[5,1-b]quinazolin-8(5H)-one chemical structure, C20H22N4O, CAS 895361-41-8

2-Ethyl-6-[4-(propan-2-yl)phenyl]-6,7-dihydro[1,2,4]triazolo[5,1-b]quinazolin-8(5H)-one

CAS 895361-41-8C₂₀H₂₂N₄O

6-(4-Fluorophenyl)-6,7-dihydro[1,2,4]triazolo[5,1-b]quinazolin-8(5H)-one chemical structure, C15H11FN4O, CAS 941256-78-6

6-(4-Fluorophenyl)-6,7-dihydro[1,2,4]triazolo[5,1-b]quinazolin-8(5H)-one

CAS 941256-78-6C₁₅H₁₁FN₄O

Methyl 2-[[6-(4-fluorophenyl)-5,6,7,8-tetrahydro-8-oxo[1,2,4]triazolo[5,1-b]quinazolin-2-yl]thio]acetate chemical structure, C18H15FN4O3S, CAS 941256-93-5

Methyl 2-[[6-(4-fluorophenyl)-5,6,7,8-tetrahydro-8-oxo[1,2,4]triazolo[5,1-b]quinazolin-2-yl]thio]acetate

CAS 941256-93-5C₁₈H₁₅FN₄O₃S

2-Ethyl-6-(4-methoxyphenyl)-6,7-dihydro[1,2,4]triazolo[5,1-b]quinazolin-8(5H)-one chemical structure, C18H18N4O2, CAS 941257-20-1

2-Ethyl-6-(4-methoxyphenyl)-6,7-dihydro[1,2,4]triazolo[5,1-b]quinazolin-8(5H)-one

CAS 941257-20-1C₁₈H₁₈N₄O₂

6-(4-Methoxyphenyl)-6,7-dihydro[1,2,4]triazolo[5,1-b]quinazolin-8(5H)-one chemical structure, C16H14N4O2, CAS 940999-19-9

6-(4-Methoxyphenyl)-6,7-dihydro[1,2,4]triazolo[5,1-b]quinazolin-8(5H)-one

CAS 940999-19-9C₁₆H₁₄N₄O₂

6-(4-Methoxyphenyl)-2-methyl-6,7-dihydro[1,2,4]triazolo[5,1-b]quinazolin-8(5H)-one chemical structure, C17H16N4O2, CAS 941257-23-4

6-(4-Methoxyphenyl)-2-methyl-6,7-dihydro[1,2,4]triazolo[5,1-b]quinazolin-8(5H)-one

CAS 941257-23-4C₁₇H₁₆N₄O₂

6-(4-Methoxyphenyl)-2-(methylthio)-6,7-dihydro[1,2,4]triazolo[5,1-b]quinazolin-8(5H)-one chemical structure, C17H16N4O2S, CAS 941257-26-7

6-(4-Methoxyphenyl)-2-(methylthio)-6,7-dihydro[1,2,4]triazolo[5,1-b]quinazolin-8(5H)-one

CAS 941257-26-7C₁₇H₁₆N₄O₂S

Methyl {[6-(4-methoxyphenyl)-8-oxo-5,6,7,8-tetrahydro[1,2,4]triazolo[5,1-b]quinazolin-2-yl]sulfanyl}acetate chemical structure, C19H18N4O4S, CAS 941257-44-9

Methyl {[6-(4-methoxyphenyl)-8-oxo-5,6,7,8-tetrahydro[1,2,4]triazolo[5,1-b]quinazolin-2-yl]sulfanyl}acetate

CAS 941257-44-9C₁₉H₁₈N₄O₄S

6-(4-Methoxyphenyl)-2-(propylsulfanyl)-6,7-dihydro[1,2,4]triazolo[5,1-b]quinazolin-8(5H)-one chemical structure, C19H20N4O2S, CAS 941257-90-5

6-(4-Methoxyphenyl)-2-(propylsulfanyl)-6,7-dihydro[1,2,4]triazolo[5,1-b]quinazolin-8(5H)-one

CAS 941257-90-5C₁₉H₂₀N₄O₂S

6-[4-(Propan-2-yl)phenyl]-6,7-dihydro[1,2,4]triazolo[5,1-b]quinazolin-8(5H)-one chemical structure, C18H18N4O, CAS 941257-99-4

6-[4-(Propan-2-yl)phenyl]-6,7-dihydro[1,2,4]triazolo[5,1-b]quinazolin-8(5H)-one

CAS 941257-99-4C₁₈H₁₈N₄O

2-(Ethylsulfanyl)-6-phenyl-6,7-dihydro[1,2,4]triazolo[5,1-b]quinazolin-8(5H)-one chemical structure, C17H16N4OS, CAS 945343-09-9

2-(Ethylsulfanyl)-6-phenyl-6,7-dihydro[1,2,4]triazolo[5,1-b]quinazolin-8(5H)-one

CAS 945343-09-9C₁₇H₁₆N₄OS

6-Phenyl-2-(propylsulfanyl)-6,7-dihydro[1,2,4]triazolo[5,1-b]quinazolin-8(5H)-one chemical structure, C18H18N4OS, CAS 945310-84-9

6-Phenyl-2-(propylsulfanyl)-6,7-dihydro[1,2,4]triazolo[5,1-b]quinazolin-8(5H)-one

CAS 945310-84-9C₁₈H₁₈N₄OS

2-Ethyl-6-(4-methylphenyl)-6,7-dihydro[1,2,4]triazolo[5,1-b]quinazolin-8(5H)-one chemical structure, C18H18N4O, CAS 945310-90-7

2-Ethyl-6-(4-methylphenyl)-6,7-dihydro[1,2,4]triazolo[5,1-b]quinazolin-8(5H)-one

CAS 945310-90-7C₁₈H₁₈N₄O

6-(4-Methylphenyl)-6,7-dihydro[1,2,4]triazolo[5,1-b]quinazolin-8(5H)-one chemical structure, C16H14N4O, CAS 945343-18-0

6-(4-Methylphenyl)-6,7-dihydro[1,2,4]triazolo[5,1-b]quinazolin-8(5H)-one

CAS 945343-18-0C₁₆H₁₄N₄O

6-(4-Methylphenyl)-2-(methylsulfanyl)-6,7-dihydro[1,2,4]triazolo[5,1-b]quinazolin-8(5H)-one chemical structure, C17H16N4OS, CAS 945310-96-3

6-(4-Methylphenyl)-2-(methylsulfanyl)-6,7-dihydro[1,2,4]triazolo[5,1-b]quinazolin-8(5H)-one

CAS 945310-96-3C₁₇H₁₆N₄OS

6-(4-Chlorophenyl)-6,7-dihydro[1,2,4]triazolo[5,1-b]quinazolin-8(5H)-one chemical structure, C15H11ClN4O, CAS 945311-28-4

6-(4-Chlorophenyl)-6,7-dihydro[1,2,4]triazolo[5,1-b]quinazolin-8(5H)-one

CAS 945311-28-4C₁₅H₁₁ClN₄O