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Murcko scaffold

Ring system with 5 rings and 22 atoms

5 chemicals on CompoundList share this ring system.

Rings
5
Scaffold atoms
22
Chemicals
5
With full pages
2
Scaffold SMILES

O=C1c2cc3c(cc2-c2[nH]c(=O)c4ccccc4c21)OCO3

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1c2cc3c(cc2-c2[nH]c(=O)c4ccccc4c21)OCO3

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 5 of 5 chemicals

5,6-Dihydro-5,11-diketo-2,3-dimethoxy-6-methyl-8,9-methylenedioxy-11H-indeno(1,2-c)isoquinoline chemical structure, C20H15NO6, CAS 66358-49-4
5,6-Dihydro-5,11-diketo-2,3-dimethoxy-6-methyl-8,9-methylenedioxy-11H-indeno(1,2-c)isoquinoline
CAS 66358-49-4C20H15NO6
LMP-744 hydrochloride chemical structure, C24H25ClN2O7, CAS 308246-57-3
LMP-744 hydrochloride
CAS 308246-57-3C24H25ClN2O7
5H-(1,3)Dioxolo(5,6)indeno(1,2-C)isoquinoline-5,12(6H)-dione, 6-(3-((2-hydroxyethyl)amino)propyl)-2,3-dimethoxy- chemical structure, C24H24N2O7, CAS 308246-52-8
5H-(1,3)Dioxolo(5,6)indeno(1,2-C)isoquinoline-5,12(6H)-dione, 6-(3-((2-hydroxyethyl)amino)propyl)-2,3-dimethoxy-
CAS 308246-52-8C24H24N2O7
6-(3-Chloropropyl)-2,3-dimethoxy-5H-[1,3]dioxolo[4',5':5,6]indeno[1,2-c]isoquinoline-5,12(6H)-dione chemical structure, C22H18ClNO6, CAS 308246-42-6
6-(3-Chloropropyl)-2,3-dimethoxy-5H-[1,3]dioxolo[4',5':5,6]indeno[1,2-c]isoquinoline-5,12(6H)-dione
CAS 308246-42-6C22H18ClNO6
16-Fluoro-20-[3-(2-hydroxyethylamino)propyl]-5,7-dioxa-20-azapentacyclo[10.8.0.02,10.04,8.013,18]icosa-1(12),2,4(8),9,13(18),14,16-heptaene-11,19-dione chemical structure, C22H19FN2O5, CAS 1883730-99-1
16-Fluoro-20-[3-(2-hydroxyethylamino)propyl]-5,7-dioxa-20-azapentacyclo[10.8.0.02,10.04,8.013,18]icosa-1(12),2,4(8),9,13(18),14,16-heptaene-11,19-dione
CAS 1883730-99-1C22H19FN2O5