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Murcko scaffold

8-Oxa-3,5-diazatricyclo[7.4.0.0,2,7]trideca-1(13),2(7),3,9,11-pentaen-6-one scaffold

26 chemicals on CompoundList share this ring system.

Rings: 3
Scaffold atoms: 14
Chemicals: 26
With full pages: 12

Scaffold SMILES

O=c1[nH]cnc2c1oc1ccccc12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold Open the 8-Oxa-3,5-diazatricyclo[7.4.0.0,2,7]trideca-1(13),2(7),3,9,11-pentaen-6-one page

Murcko scaffold O=c1[nH]cnc2c1oc1ccccc12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 26 of 26 chemicals

2-[[3-(3-Ethoxypropyl)-4-oxo-[1]benzofuro[3,2-d]pyrimidin-2-yl]sulfanyl]acetamide chemical structure, C17H19N3O4S, CAS 866894-81-7

2-[[3-(3-Ethoxypropyl)-4-oxo-[1]benzofuro[3,2-d]pyrimidin-2-yl]sulfanyl]acetamide

CAS 866894-81-7C₁₇H₁₉N₃O₄S

Ethyl (4-oxo[1]benzofuro[3,2-{d}]pyrimidin-3(4{H})-yl)acetate chemical structure, C14H12N2O4, CAS 257613-43-7

Ethyl (4-oxo[1]benzofuro[3,2-{d}]pyrimidin-3(4{H})-yl)acetate

CAS 257613-43-7C₁₄H₁₂N₂O₄

2-(4-Oxo-[1]benzofuro[3,2-d]pyrimidin-3-yl)acetonitrile chemical structure, C12H7N3O2, CAS 849046-18-0

2-(4-Oxo-[1]benzofuro[3,2-d]pyrimidin-3-yl)acetonitrile

CAS 849046-18-0C₁₂H₇N₃O₂

N-(3-Methylbutan-2-yl)-2-(4-oxo-[1]benzofuro[3,2-d]pyrimidin-3-yl)acetamide chemical structure, C17H19N3O3, CAS 849515-34-0

N-(3-Methylbutan-2-yl)-2-(4-oxo-[1]benzofuro[3,2-d]pyrimidin-3-yl)acetamide

CAS 849515-34-0C₁₇H₁₉N₃O₃

4-Oxobenzofuro[3,2-d]pyrimidine-3(4H)-acetic acid chemical structure, C12H8N2O4, CAS 257613-44-8

4-Oxobenzofuro[3,2-d]pyrimidine-3(4H)-acetic acid

CAS 257613-44-8C₁₂H₈N₂O₄

3-Propylbenzofuro[3,2-d]pyrimidin-4(3H)-one chemical structure, C13H12N2O2, CAS 75746-13-3

3-Propylbenzofuro[3,2-d]pyrimidin-4(3H)-one

CAS 75746-13-3C₁₃H₁₂N₂O₂

$Methyl 2-(2-{6-oxo-8-oxa-3,5-diazatricyclo[7.4.0.0^{2,7}]trideca-1(13),2(7),3,9,11-pentaen-5-yl}acetamido)acetate chemical structure, C15H13N3O5, CAS 950272-70-5$

Methyl 2-(2-{6-oxo-8-oxa-3,5-diazatricyclo[7.4.0.0^{2,7}]trideca-1(13),2(7),3,9,11-pentaen-5-yl}acetamido)acetate

CAS 950272-70-5C₁₅H₁₃N₃O₅

3-(Prop-2-yn-1-yl)benzofuro[3,2-d]pyrimidin-4(3H)-one chemical structure, C13H8N2O2, CAS 864922-99-6

3-(Prop-2-yn-1-yl)benzofuro[3,2-d]pyrimidin-4(3H)-one

CAS 864922-99-6C₁₃H₈N₂O₂

Ethyl 2-(2-(4-oxobenzofuro[3,2-d]pyrimidin-3(4H)-yl)acetamido)acetate chemical structure, C16H15N3O5, CAS 864923-19-3

Ethyl 2-(2-(4-oxobenzofuro[3,2-d]pyrimidin-3(4H)-yl)acetamido)acetate

CAS 864923-19-3C₁₆H₁₅N₃O₅

Methyl 2-(4-oxobenzofuro[3,2-d]pyrimidin-3(4H)-yl)acetate chemical structure, C13H10N2O4, CAS 864923-33-1

Methyl 2-(4-oxobenzofuro[3,2-d]pyrimidin-3(4H)-yl)acetate

CAS 864923-33-1C₁₃H₁₀N₂O₄

3-({5-Methyl-6-oxo-8-oxa-3,5-diazatricyclo[7.4.0.0,2,7]trideca-1(9),2(7),3,10,12-pentaen-4-yl}sulfanyl)propanoic acid chemical structure, C14H12N2O4S, CAS 1185373-92-5

3-({5-Methyl-6-oxo-8-oxa-3,5-diazatricyclo[7.4.0.0,2,7]trideca-1(9),2(7),3,10,12-pentaen-4-yl}sulfanyl)propanoic acid

CAS 1185373-92-5C₁₄H₁₂N₂O₄S

4-(Chloromethyl)-8-oxa-3,5-diazatricyclo[7.4.0.0,2,7]trideca-1(13),2(7),3,9,11-pentaen-6-one chemical structure, C11H7ClN2O2, CAS 80550-76-1

4-(Chloromethyl)-8-oxa-3,5-diazatricyclo[7.4.0.0,2,7]trideca-1(13),2(7),3,9,11-pentaen-6-one

CAS 80550-76-1C₁₁H₇ClN₂O₂

8-Chloro-2-methyl[1]benzofuro[3,2-d]pyrimidin-4(3H)-one chemical structure, C11H7ClN2O2, CAS 33149-50-7

8-Chloro-2-methyl[1]benzofuro[3,2-d]pyrimidin-4(3H)-one

CAS 33149-50-7C₁₁H₇ClN₂O₂

2-(Hydroxymethyl)benzofuro[3,2-d]pyrimidin-4(3H)-one chemical structure, C11H8N2O3, CAS 80550-77-2

2-(Hydroxymethyl)benzofuro[3,2-d]pyrimidin-4(3H)-one

CAS 80550-77-2C₁₁H₈N₂O₃

8-Oxa-3,5-diazatricyclo[7.4.0.0,2,7]trideca-1(13),2(7),3,9,11-pentaen-6-one chemical structure, C10H6N2O2, CAS 39786-36-2

8-Oxa-3,5-diazatricyclo[7.4.0.0,2,7]trideca-1(13),2(7),3,9,11-pentaen-6-one

CAS 39786-36-2C₁₀H₆N₂O₂

8-Chloro[1]benzofuro[3,2-d]pyrimidin-4(3H)-one chemical structure, C10H5ClN2O2, CAS 328277-09-4

8-Chloro[1]benzofuro[3,2-d]pyrimidin-4(3H)-one

CAS 328277-09-4C₁₀H₅ClN₂O₂

2-Methyl[1]benzofuro[3,2-d]pyrimidin-4(3H)-one chemical structure, C11H8N2O2, CAS 33149-48-3

2-Methyl[1]benzofuro[3,2-d]pyrimidin-4(3H)-one

CAS 33149-48-3C₁₁H₈N₂O₂

2-(Methylsulfanyl)[1]benzofuro[3,2-d]pyrimidin-4(3H)-one chemical structure, C11H8N2O2S, CAS 1008108-37-9

2-(Methylsulfanyl)[1]benzofuro[3,2-d]pyrimidin-4(3H)-one

CAS 1008108-37-9C₁₁H₈N₂O₂S

8-Methylbenzofuro[3,2-d]pyrimidin-4(3H)-one chemical structure, C11H8N2O2, CAS 1228148-48-8

8-Methylbenzofuro[3,2-d]pyrimidin-4(3H)-one

CAS 1228148-48-8C₁₁H₈N₂O₂

Methyl 8-bromo-4-oxo-1,4-dihydrobenzofuro[3,2-d]pyrimidine-2-carboxylate chemical structure, C12H7BrN2O4, CAS 1169560-45-5

Methyl 8-bromo-4-oxo-1,4-dihydrobenzofuro[3,2-d]pyrimidine-2-carboxylate

CAS 1169560-45-5C₁₂H₇BrN₂O₄

8-Bromo-2-chlorobenzofuro[3,2-d]pyrimidin-4(3H)-one chemical structure, C10H4BrClN2O2, CAS 1169560-05-7

8-Bromo-2-chlorobenzofuro[3,2-d]pyrimidin-4(3H)-one

CAS 1169560-05-7C₁₀H₄BrClN₂O₂

2-(Aminomethyl)-8-bromo[1]benzofuro[3,2-d]pyrimidin-4(3H)-one chemical structure, C11H8BrN3O2, CAS 1169552-90-2

2-(Aminomethyl)-8-bromo[1]benzofuro[3,2-d]pyrimidin-4(3H)-one

CAS 1169552-90-2C₁₁H₈BrN₃O₂

8-Bromo-2-(chloromethyl)benzofuro[3,2-d]pyrimidin-4(3H)-one chemical structure, C11H6BrClN2O2, CAS 1169559-18-5

8-Bromo-2-(chloromethyl)benzofuro[3,2-d]pyrimidin-4(3H)-one

CAS 1169559-18-5C₁₁H₆BrClN₂O₂

8-Bromo-2-(methylthio)benzofuro[3,2-d]pyrimidin-4(3H)-one chemical structure, C11H7BrN2O2S, CAS 1169560-69-3

8-Bromo-2-(methylthio)benzofuro[3,2-d]pyrimidin-4(3H)-one

CAS 1169560-69-3C₁₁H₇BrN₂O₂S